[Merge] MONDO:0009453 'immune deficiency disease'

[nicolevasilevsky]

Mondo term (ID and Label)
MONDO:0009453 'immune deficiency disease'

Reason for deprecation
@sabrinatoro can you please review this?

The term above is equiv to this OMIM class: https://omim.org/entry/242850

whereas the term below is equiv to an OMIMPS:
https://www.omim.org/phenotypicSeries/PS300755,PS601495

Maybe it it just best to obsolete the term above? Or rename it? It's very confusing. Or maybe the OMIM term should be the non-heriditary form? It doesn't mention inheritance in the description.

We have acquired immunodeficiency and two inherited classes (those mentioned here) and maybe we need a grouping triad?

Term to be merged with
MONDO:0021094 'immunodeficiency disease'

[sabrinatoro]

@nicolevasilevsky
Here is what I have found:

• MONDO:0009453 'immune deficiency disease': OMIM:242850 is a VERY old record (1973, reviewed last 2009). And the MESH id refers to this OMIMid.
  I don't know enough about immunodeficiency, but the record suspects IgM deficiency.
  So, I would obsolete this term based on historical reasons.

The questions now are:

1. Is this term the same as "immunodeficiency disease" (and ie should be merged)?
   I cannot tell that these terms report to the same concept. I don't think for sure (the description in OMIM:242850 seems to describe a disease that is an immunodeficiency disease, but is more specific than the general "immunodeficiency disease". So I personally would lean towards obsoleting MONDO:0009453 instead of merging it.

2. What should we do with the children of MONDO:0009453?
   Based on here: immunodeficiency (MONDO:0021094) :

• results from a failure or absence of elements of the immune system, including lymphocytes, phagocytes, and the complement system.
• have 2 "main" types:
  - primary immunodeficiency = inborn errors of immunity (MONDO:0003778)
  - hereditary, caused by genetic mutation that affect the immune system
  - subdivided into types: T-cell deficiency, B-cell deficiency, both T-cell and B-cell deficiency, complement deficiency, phagocyte deficiency, Immunoglobulin A deficiency.
  - publication
  - secondary immunodeficiency = acquired immunodeficiency (I think)
  - caused by steroid, obesity, AIDS,...
  Therefore, I think the children of the current MONDO:0009453 can be moved to "MONDO:0021094 'immunodeficiency disease'"

[sabrinatoro]

I did not add to the merge list as it is unclear whether we want this term to be merged or obsoleted.

[sabrinatoro]

Question:
is there a difference between "immune deficiency disease" and "immunodeficiency disease"?

[sabrinatoro]

closing in favor of #7461