diff --git a/onnxruntime/test/python/quantization/test_quant_util.py b/onnxruntime/test/python/quantization/test_quant_util.py
index 33ddabcedd826..4faa8e93c40b5 100644
--- a/onnxruntime/test/python/quantization/test_quant_util.py
+++ b/onnxruntime/test/python/quantization/test_quant_util.py
@@ -36,6 +36,8 @@ def test_compute_scale_zp(self):
         # Test enforcing a minimum floatint-point range.
         self.assertEqual(compute_scale_zp(0.0, 0.0, 0, 255, symmetric=False, min_rrange=0.0001), [0, 0.0001 / 255])
         self.assertEqual(compute_scale_zp(0.0, 0.0, -128, 127, symmetric=True, min_rrange=0.0001), [0, 0.0002 / 255])
+        self.assertEqual(compute_scale_zp(0.0, 0.0, 0, 65535, symmetric=False, min_rrange=0.0001), [0, 0.0001 / 65535])
+        self.assertEqual(compute_scale_zp(0.0, 0.0, -32768, 32767, symmetric=True, min_rrange=0.0001), [0, 0.0002 / 65535])
 
     def test_load_external_model(self):
         input_name = "input"