diff --git a/cmake/onnxruntime_unittests.cmake b/cmake/onnxruntime_unittests.cmake
index 15437c6037c95..c64f029ad9301 100644
--- a/cmake/onnxruntime_unittests.cmake
+++ b/cmake/onnxruntime_unittests.cmake
@@ -1657,7 +1657,7 @@ if (NOT CMAKE_SYSTEM_NAME STREQUAL "Emscripten")
       list(APPEND onnxruntime_customopregistration_test_LIBS ${TENSORRT_LIBRARY_INFER})
     endif()
     if (${CMAKE_SYSTEM_NAME} MATCHES "AIX")
-      list(APPEND onnxruntime_customopregistration_test_LIBS onnxruntime_graph onnxruntime_session onnxruntime_providers onnxruntime_framework onnxruntime_util onnxruntime_mlas onnxruntime_optimizer onnxruntime_flatbuffers iconv re2 libprotobuf-lite onnx_proto nsync_cpp)
+      list(APPEND onnxruntime_customopregistration_test_LIBS onnxruntime_graph onnxruntime_session onnxruntime_providers onnxruntime_lora onnxruntime_framework onnxruntime_util onnxruntime_mlas onnxruntime_optimizer onnxruntime_flatbuffers iconv re2 libprotobuf-lite onnx_proto nsync_cpp)
     endif()
     AddTest(DYN
             TARGET onnxruntime_customopregistration_test
diff --git a/csharp/src/Microsoft.ML.OnnxRuntime/NativeMethods.shared.cs b/csharp/src/Microsoft.ML.OnnxRuntime/NativeMethods.shared.cs
index b2a7b75891a25..be157a0419fc0 100644
--- a/csharp/src/Microsoft.ML.OnnxRuntime/NativeMethods.shared.cs
+++ b/csharp/src/Microsoft.ML.OnnxRuntime/NativeMethods.shared.cs
@@ -302,6 +302,29 @@ public struct OrtApi
         public IntPtr ReleaseROCMProviderOptions;
         public IntPtr CreateAndRegisterAllocatorV2;
         public IntPtr RunAsync;
+        public IntPtr UpdateTensorRTProviderOptionsWithValue;
+        public IntPtr GetTensorRTProviderOptionsByName;
+        public IntPtr UpdateCUDAProviderOptionsWithValue;
+        public IntPtr GetCUDAProviderOptionsByName;
+        public IntPtr KernelContext_GetResource;
+        public IntPtr SetUserLoggingFunction;
+        public IntPtr ShapeInferContext_GetInputCount;
+        public IntPtr ShapeInferContext_GetInputTypeShape;
+        public IntPtr ShapeInferContext_GetAttribute;
+        public IntPtr ShapeInferContext_SetOutputTypeShape;
+        public IntPtr SetSymbolicDimensions;
+        public IntPtr ReadOpAttr;
+        public IntPtr SetDeterministicCompute;
+        public IntPtr KernelContext_ParallelFor;
+        public IntPtr SessionOptionsAppendExecutionProvider_OpenVINO_V2;
+        public IntPtr SessionOptionsAppendExecutionProvider_VitisAI;
+        public IntPtr KernelContext_GetScratchBuffer;
+        public IntPtr KernelInfoGetAllocator;
+        public IntPtr AddExternalInitializersFromFilesInMemory;
+        public IntPtr CreateLoraAdapter;
+        public IntPtr CreateLoraAdapterFromArray;
+        public IntPtr ReleaseLoraAdapter;
+        public IntPtr RunOptionsAddActiveLoraAdapter;
     }
 
     internal static class NativeMethods
@@ -540,6 +563,13 @@ static NativeMethods()
             OrtReleaseROCMProviderOptions = (DOrtReleaseROCMProviderOptions)Marshal.GetDelegateForFunctionPointer(api_.ReleaseROCMProviderOptions, typeof(DOrtReleaseROCMProviderOptions));
             OrtCreateAndRegisterAllocatorV2 = (DCreateAndRegisterAllocatorV2)Marshal.GetDelegateForFunctionPointer(api_.CreateAndRegisterAllocatorV2, typeof(DCreateAndRegisterAllocatorV2));
             OrtRunAsync = (DOrtRunAsync)Marshal.GetDelegateForFunctionPointer(api_.RunAsync, typeof(DOrtRunAsync));
+            CreateLoraAdapter = (DCreateLoraAdapter)Marshal.GetDelegateForFunctionPointer(api_.CreateLoraAdapter,
+                typeof(DCreateLoraAdapter));
+            CreateLoraAdapterFromArray = (DCreateLoraAdapterFromArray)Marshal.GetDelegateForFunctionPointer (api_.CreateLoraAdapterFromArray, typeof(DCreateLoraAdapterFromArray));
+            ReleaseLoraAdapter = (DReleaseLoraAdapter)Marshal.GetDelegateForFunctionPointer(api_.ReleaseLoraAdapter,
+                typeof(DReleaseLoraAdapter));
+            OrtRunOptionsAddActiveLoraAdapter = (DOrtRunOptionsAddActiveLoraAdapter)Marshal.GetDelegateForFunctionPointer(
+                api_.RunOptionsAddActiveLoraAdapter, typeof(DOrtRunOptionsAddActiveLoraAdapter));
         }
 
         internal class NativeLib
@@ -1263,7 +1293,49 @@ IntPtr[] outputValues /* An array of output value pointers. Array must be alloca
 
 #endregion
 
-#region RunOptions API
+#region LoraAdapter API
+        /// <summary>
+        /// Memory maps the adapter file, wraps it into the adapter object
+        /// and returns it.
+        /// </summary>
+        /// <param name="adapter_path">absolute path to the adapter file</param>
+        /// <param name="allocator">optional device allocator or null</param>
+        /// <param name="lora_adapter">New LoraAdapter object</param>
+        /// <returns></returns>
+        [UnmanagedFunctionPointer(CallingConvention.Winapi)]
+        public delegate IntPtr /*(OrtStatus*)*/ DCreateLoraAdapter(
+                byte[] adapter_path, // This takes const ORTCHAR_T* use GetPlatformSerializedString
+                IntPtr /* OrtAllocator */ allocator, // optional
+                out IntPtr lora_adapter
+            );
+        public static DCreateLoraAdapter CreateLoraAdapter;
+
+        /// <summary>
+        /// Creates LoraAdapter instance from a byte array that must
+        /// represents a valid LoraAdapter formst.
+        /// </summary>
+        /// <param name="bytes">bytes</param>
+        /// <param name="size">size in bytes</param>
+        /// <param name="allocator">optional device allocator</param>
+        /// <param name="lora_adapter">resuling LoraAdapter instance</param>
+        /// <returns></returns>
+        [UnmanagedFunctionPointer(CallingConvention.Winapi)]
+        public delegate IntPtr /*(OrtStatus*)*/ DCreateLoraAdapterFromArray(
+                byte[] bytes,
+                UIntPtr size,
+                IntPtr /* OrtAllocator */ allocator, // optional
+                out IntPtr lora_adapter
+            );
+        public static DCreateLoraAdapterFromArray CreateLoraAdapterFromArray;
+
+
+        [UnmanagedFunctionPointer(CallingConvention.Winapi)]
+        public delegate void DReleaseLoraAdapter(IntPtr /* OrtLoraAdapter* */ lora_adapter);
+        public static DReleaseLoraAdapter ReleaseLoraAdapter;
+
+#endregion
+
+    #region RunOptions API
 
         [UnmanagedFunctionPointer(CallingConvention.Winapi)]
         public delegate IntPtr /*(OrtStatus*)*/ DOrtCreateRunOptions(out IntPtr /* OrtRunOptions** */ runOptions);
@@ -1308,6 +1380,12 @@ IntPtr[] outputValues /* An array of output value pointers. Array must be alloca
         public delegate IntPtr /*(OrtStatus*)*/ DOrtRunOptionsUnsetTerminate(IntPtr /* OrtRunOptions* */ options);
         public static DOrtRunOptionsUnsetTerminate OrtRunOptionsUnsetTerminate;
 
+        [UnmanagedFunctionPointer(CallingConvention.Winapi)]
+        public delegate IntPtr /*(OrtStatus*)*/ DOrtRunOptionsAddActiveLoraAdapter(
+            IntPtr /* OrtRunOptions* */ options,
+            IntPtr /* OrtLoraAdapter* */ lora_adapter);
+        public static DOrtRunOptionsAddActiveLoraAdapter OrtRunOptionsAddActiveLoraAdapter;
+
         /// <summary>
         /// Add run config entry
         /// </summary>
diff --git a/csharp/src/Microsoft.ML.OnnxRuntime/OrtLoraAdapter.shared.cs b/csharp/src/Microsoft.ML.OnnxRuntime/OrtLoraAdapter.shared.cs
new file mode 100644
index 0000000000000..e2249b4c47fec
--- /dev/null
+++ b/csharp/src/Microsoft.ML.OnnxRuntime/OrtLoraAdapter.shared.cs
@@ -0,0 +1,81 @@
+// Copyright (c) Microsoft Corporation. All rights reserved.
+// Licensed under the MIT License.
+using System;
+using System.Runtime.InteropServices;
+
+namespace Microsoft.ML.OnnxRuntime
+{
+    /// <summary>
+    /// Represents Lora Adapter in memory
+    /// </summary>
+    public class OrtLoraAdapter : SafeHandle
+    {
+        /// <summary>
+        /// Creates an instance of OrtLoraAdapter from file.
+        /// The adapter file is memory mapped. If allocator parameter
+        /// is provided, then lora parameters are copied to the memory
+        /// allocated by the specified allocator.
+        /// </summary>
+        /// <param name="adapterPath">path to the adapter file</param>
+        /// <param name="ortAllocator">optional allocator, can be null, must be a device allocator</param>
+        /// <returns>New instance of LoraAdapter</returns>
+        public static OrtLoraAdapter Create(string adapterPath, OrtAllocator ortAllocator)
+        {
+            var platformPath = NativeOnnxValueHelper.GetPlatformSerializedString(adapterPath);
+            var allocatorHandle = (ortAllocator != null) ? ortAllocator.Pointer : IntPtr.Zero;
+            NativeApiStatus.VerifySuccess(NativeMethods.CreateLoraAdapter(platformPath, allocatorHandle,
+                out IntPtr adapterHandle));
+            return new OrtLoraAdapter(adapterHandle);
+        }
+
+        /// <summary>
+        /// Creates an instance of OrtLoraAdapter from an array of bytes. The API
+        /// makes a copy of the bytes internally.
+        /// </summary>
+        /// <param name="bytes">array of bytes containing valid LoraAdapter format</param>
+        /// <param name="ortAllocator">optional device allocator or null</param>
+        /// <returns>new instance of LoraAdapter</returns>
+        public static OrtLoraAdapter Create(byte[] bytes, OrtAllocator ortAllocator)
+        {
+            var allocatorHandle = (ortAllocator != null) ? ortAllocator.Pointer : IntPtr.Zero;
+            NativeApiStatus.VerifySuccess(NativeMethods.CreateLoraAdapterFromArray(bytes, 
+                new UIntPtr((uint)bytes.Length), allocatorHandle, out IntPtr adapterHandle));
+            return new OrtLoraAdapter(adapterHandle);
+        }
+
+        internal OrtLoraAdapter(IntPtr adapter)
+            : base(adapter, true)
+        {
+        }
+
+        internal IntPtr Handle
+        {
+            get
+            {
+                return handle;
+            }
+        }
+
+        #region SafeHandle
+
+        /// <summary>
+        /// Overrides SafeHandle.IsInvalid
+        /// </summary>
+        /// <value>returns true if handle is equal to Zero</value>
+        public override bool IsInvalid { get { return handle == IntPtr.Zero; } }
+
+        /// <summary>
+        /// Overrides SafeHandle.ReleaseHandle() to properly dispose of
+        /// the native instance of OrtLoraAdapter
+        /// </summary>
+        /// <returns>always returns true</returns>
+        protected override bool ReleaseHandle()
+        {
+            NativeMethods.ReleaseLoraAdapter(handle);
+            handle = IntPtr.Zero;
+            return true;
+        }
+
+        #endregion
+    }
+}
diff --git a/csharp/src/Microsoft.ML.OnnxRuntime/RunOptions.shared.cs b/csharp/src/Microsoft.ML.OnnxRuntime/RunOptions.shared.cs
index d01c0f6e6fe4d..20547d6757b79 100644
--- a/csharp/src/Microsoft.ML.OnnxRuntime/RunOptions.shared.cs
+++ b/csharp/src/Microsoft.ML.OnnxRuntime/RunOptions.shared.cs
@@ -129,6 +129,18 @@ public void AddRunConfigEntry(string configKey, string configValue)
             NativeApiStatus.VerifySuccess(NativeMethods.OrtAddRunConfigEntry(handle, utf8Key, utf8Value));
         }
 
+        /// <summary>
+        /// Appends the specified lora adapter to the list of active lora adapters
+        /// for this RunOptions instance. All run calls with this instant will
+        /// make use of the activated Lora Adapters. An adapter is considered active
+        /// if it is added to RunOptions that are used during Run() calls.
+        /// </summary>
+        /// <param name="loraAdapter">Lora adapter instance</param>
+        public void AddActiveLoraAdapter(OrtLoraAdapter loraAdapter)
+        {
+            NativeApiStatus.VerifySuccess(NativeMethods.OrtRunOptionsAddActiveLoraAdapter(handle, loraAdapter.Handle));
+        }
+
         #region SafeHandle
         /// <summary>
         /// Overrides SafeHandle.ReleaseHandle() to properly dispose of
diff --git a/csharp/test/Microsoft.ML.OnnxRuntime.Tests.Common/InferenceTest.cs b/csharp/test/Microsoft.ML.OnnxRuntime.Tests.Common/InferenceTest.cs
index ac7a84d69bbea..aa0e6ee62248a 100644
--- a/csharp/test/Microsoft.ML.OnnxRuntime.Tests.Common/InferenceTest.cs
+++ b/csharp/test/Microsoft.ML.OnnxRuntime.Tests.Common/InferenceTest.cs
@@ -1678,6 +1678,7 @@ private void TestInferenceSessionWithByteArray()
             }
         }
 
+
         void TestCPUAllocatorInternal(InferenceSession session)
         {
             int device_id = 0;
diff --git a/csharp/test/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp/InferenceTest.netcore.cs b/csharp/test/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp/InferenceTest.netcore.cs
index ad127c2579294..ff5fd2de54197 100644
--- a/csharp/test/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp/InferenceTest.netcore.cs
+++ b/csharp/test/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp/InferenceTest.netcore.cs
@@ -680,7 +680,7 @@ private void RunPretrainedModel(InferenceSession session, RunOptions runOptions,
 
             var orderedInputNames = new List<string>(inputContainer.Count);
             var orderdedInputs = new List<OrtValue>(inputContainer.Count);
-            foreach(var pair in inputContainer)
+            foreach (var pair in inputContainer)
             {
                 orderedInputNames.Add(pair.Key);
                 orderdedInputs.Add(pair.Value);
@@ -772,7 +772,7 @@ private void TestPreTrainedModels(string opsetDir, string modelName, bool useOrt
                     throw new Exception($"Opset {opset} Model {modelName}. Can't determine model file name. Found these :{modelNamesList}");
                 }
 
-                using(var runOptions = new RunOptions())
+                using (var runOptions = new RunOptions())
                 using (var session = new InferenceSession(onnxModelFileName))
                 {
                     string testDataDirNamePattern = "test_data*";
@@ -1077,7 +1077,7 @@ private static void VerifyContainerContent(IReadOnlyList<OrtValue> results,
                         Assert.Equal(result.GetStringTensorAsArray(), expectedValue.AsTensor<string>().ToArray(), new ExactComparer<string>());
                         break;
                     default:
-                        Assert.Fail($"VerifyTensorResults cannot handle ElementType: { resultTypeShape.ElementDataType}");
+                        Assert.Fail($"VerifyTensorResults cannot handle ElementType: {resultTypeShape.ElementDataType}");
                         break;
                 }
             }
@@ -1251,6 +1251,88 @@ private void TestModelSerialization()
             }
         }
 
+        private static OrtLoraAdapter CreateLoraAdapterFromFile()
+        {
+            var adapterPath = Path.Combine(Directory.GetCurrentDirectory(), "two_params_lora_model.onnx_adapter");
+            return OrtLoraAdapter.Create(adapterPath, null);
+        }
+
+        private static OrtLoraAdapter CreateLoraAdapterFromArray()
+        {
+            var adapterPath = Path.Combine(Directory.GetCurrentDirectory(), "two_params_lora_model.onnx_adapter");
+            var adapterBytes = File.ReadAllBytes(adapterPath);
+            return OrtLoraAdapter.Create(adapterBytes, null);
+        }
+
+        // See tests below for running with Lora Adapters
+        [Fact(DisplayName = "TestInferenceWithBaseLoraModel")]
+        private void TestInferenceWithBaseLoraModel()
+        {
+            var modelPath = Path.Combine(Directory.GetCurrentDirectory(), "two_params_lora_model.onnx");
+
+            var inputShape = new long[] { 4, 4 };
+            var inputData = new float[16];
+            Array.Fill(inputData, 1);
+            using var inputOrtValue = OrtValue.CreateTensorValueFromMemory(inputData, inputShape);
+
+            var expectedOutput = new float[] {
+                    28, 32, 36, 40,
+                    28, 32, 36, 40,
+                    28, 32, 36, 40,
+                    28, 32, 36, 40 };
+
+            using var session = new InferenceSession(modelPath);
+            using var runOptions = new RunOptions();
+
+            using var outputs = session.Run(runOptions, ["input_x"], [inputOrtValue], ["output"]);
+            Assert.Single(outputs);
+            var output = outputs[0].GetTensorDataAsSpan<float>();
+            Assert.Equal(expectedOutput.Length, output.Length);
+            Assert.Equal(expectedOutput, output.ToArray(), new FloatComparer());
+        }
+
+
+        private static void TestInferenceWithLoraAdapter(OrtLoraAdapter ortLoraAdapter)
+        {
+            var modelPath = Path.Combine(Directory.GetCurrentDirectory(), "two_params_lora_model.onnx");
+            var adapterPath = Path.Combine(Directory.GetCurrentDirectory(), "two_params_lora_model.onnx_adapter");
+
+            var inputShape = new long[] { 4, 4 };
+            var inputData = new float[16];
+            Array.Fill(inputData, 1);
+            using var inputOrtValue = OrtValue.CreateTensorValueFromMemory(inputData, inputShape);
+
+            var expectedOutput = new float[] {
+                  154, 176, 198, 220,
+                  154, 176, 198, 220,
+                  154, 176, 198, 220,
+                  154, 176, 198, 220 };
+
+            using var session = new InferenceSession(modelPath);
+            using var runOptions = new RunOptions();
+            runOptions.AddActiveLoraAdapter(ortLoraAdapter);
+
+            using var outputs = session.Run(runOptions, ["input_x"], [inputOrtValue], ["output"]);
+            Assert.Single(outputs);
+            var output = outputs[0].GetTensorDataAsSpan<float>();
+            Assert.Equal(expectedOutput.Length, output.Length);
+            Assert.Equal(expectedOutput, output.ToArray(), new FloatComparer());
+        }
+
+        [Fact(DisplayName = "TestInferenceWithLoraAdapterFromFile")]
+        private void TestInferenceWithLoraAdapterFromFile()
+        {
+            using var ortAdapter = CreateLoraAdapterFromFile();
+            TestInferenceWithLoraAdapter(ortAdapter);
+        }
+
+        [Fact(DisplayName = "TestInferenceWithLoraAdapterFromArray")]
+        private void TestInferenceWithLoraAdapterFromArray()
+        {
+            using var ortAdapter = CreateLoraAdapterFromArray();
+            TestInferenceWithLoraAdapter(ortAdapter);
+        }
+
         // TestGpu() will test
         //  - the CUDA EP on CUDA enabled builds
         //  - the DML EP on DML enabled builds
diff --git a/csharp/test/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp.csproj b/csharp/test/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp.csproj
index f877cc376ea90..b822c999e4d39 100644
--- a/csharp/test/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp.csproj
+++ b/csharp/test/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp/Microsoft.ML.OnnxRuntime.Tests.NetCoreApp.csproj
@@ -105,6 +105,14 @@
       <CopyToOutputDirectory>PreserveNewest</CopyToOutputDirectory>
       <Visible>false</Visible>
     </None>
+    <None Include="$(OnnxRuntimeCSharpRoot)\..\onnxruntime\test\testdata\lora\two_params_lora_model.onnx">
+      <CopyToOutputDirectory>PreserveNewest</CopyToOutputDirectory>
+      <Visible>false</Visible>
+    </None>
+    <None Include="$(OnnxRuntimeCSharpRoot)\..\onnxruntime\test\testdata\lora\two_params_lora_model.onnx_adapter">
+      <CopyToOutputDirectory>PreserveNewest</CopyToOutputDirectory>
+      <Visible>false</Visible>
+    </None>
     <BuildEnvVars Include="OnnxRuntimeBuildDirectory=$(OnnxRuntimeBuildDirectory)" />
   </ItemGroup>