diff --git a/tools/ci_build/build.py b/tools/ci_build/build.py
index aa1198102f978..dbd9b40d30425 100644
--- a/tools/ci_build/build.py
+++ b/tools/ci_build/build.py
@@ -260,6 +260,7 @@ def convert_arg_line_to_args(self, arg_line):
     )
 
     parser.add_argument("--disable_cuda_nhwc_ops", action="store_true", help="Disable CUDA NHWC ops in build.")
+    parser.add_argument("--enable_cuda_minimal_build", action="store_true", help="Enable CUDA minimal build.")
 
     # Python bindings
     parser.add_argument("--enable_pybind", action="store_true", help="Enable Python Bindings.")
@@ -1093,6 +1094,7 @@ def generate_build_tree(
         "-Donnxruntime_DISABLE_FLOAT8_TYPES=" + ("ON" if disable_float8_types else "OFF"),
         "-Donnxruntime_DISABLE_SPARSE_TENSORS=" + ("ON" if disable_sparse_tensors else "OFF"),
         "-Donnxruntime_DISABLE_OPTIONAL_TYPE=" + ("ON" if disable_optional_type else "OFF"),
+        "-Donnxruntime_CUDA_MINIMAL=" + ("ON" if args.enable_cuda_minimal_build else "OFF"),
     ]
 
     if args.rv64:
diff --git a/tools/ci_build/github/azure-pipelines/win-gpu-tensorrt-cuda-minimal-ci-pipeline.yml b/tools/ci_build/github/azure-pipelines/win-gpu-tensorrt-cuda-minimal-ci-pipeline.yml
new file mode 100644
index 0000000000000..fd2a0a473a61c
--- /dev/null
+++ b/tools/ci_build/github/azure-pipelines/win-gpu-tensorrt-cuda-minimal-ci-pipeline.yml
@@ -0,0 +1,98 @@
+##### start trigger Don't edit it manually, Please do edit set-trigger-rules.py ####
+### please do rerun set-trigger-rules.py ###
+trigger:
+  branches:
+    include:
+    - main
+    - rel-*
+  paths:
+    exclude:
+    - docs/**
+    - README.md
+    - CONTRIBUTING.md
+    - BUILD.md
+    - 'js/web'
+    - 'onnxruntime/core/providers/js'
+pr:
+  branches:
+    include:
+    - main
+    - rel-*
+  paths:
+    exclude:
+    - docs/**
+    - README.md
+    - CONTRIBUTING.md
+    - BUILD.md
+    - 'js/web'
+    - 'onnxruntime/core/providers/js'
+#### end trigger ####
+parameters:
+- name: CudaVersion
+  displayName: CUDA version
+  type: string
+  default: '12.2'
+  values:
+    - 11.8
+    - 12.2
+
+variables:
+  - template: templates/common-variables.yml
+  - name: win_trt_folder
+    ${{ if eq(parameters.CudaVersion, '11.8') }}:
+      value: ${{ variables.win_trt_folder_cuda11 }}
+    ${{ if eq(parameters.CudaVersion, '12.2') }}:
+      value: ${{ variables.win_trt_folder_cuda12 }}
+
+jobs:
+- job: 'build'
+  pool: 'onnxruntime-Win2022-GPU-A10'
+  variables:
+    MsbuildArguments: '-detailedsummary -maxcpucount -consoleloggerparameters:PerformanceSummary'
+    EnvSetupScript: setup_env_trt.bat
+    skipComponentGovernanceDetection: true
+    TODAY: $[format('{0:dd}{0:MM}{0:yyyy}', pipeline.startTime)]
+  timeoutInMinutes: 150
+  workspace:
+    clean: all
+  steps:
+  - template: templates/jobs/win-ci-prebuild-steps.yml
+    parameters:
+      EnvSetupScript: $(EnvSetupScript)
+      DownloadCUDA: true
+      DownloadTRT: true
+      BuildArch: 'x64'
+      BuildConfig: RelWithDebInfo
+      MachinePool: 'onnxruntime-Win2022-GPU-A10'
+      WithCache: true
+      Today: $(Today)
+
+  - template: templates/jobs/win-ci-build-steps.yml
+    parameters:
+      WithCache: True
+      Today: $(TODAY)
+      AdditionalKey: "gpu-tensorrt | RelWithDebInfo"
+      BuildPyArguments: '--config RelWithDebInfo --parallel --use_binskim_compliant_compile_flags --build_dir $(Build.BinariesDirectory) --skip_submodule_sync --build_shared_lib --update --cmake_generator "Visual Studio 17 2022" --build_wheel --enable_onnx_tests --use_tensorrt --tensorrt_home="$(Agent.TempDirectory)\${{ variables.win_trt_folder }}" --cuda_home="$(Agent.TempDirectory)\v${{ parameters.CudaVersion }}" --cmake_extra_defines CMAKE_CUDA_ARCHITECTURES=86 --enable_cuda_minimal_build'
+      MsbuildArguments: $(MsbuildArguments)
+      BuildArch: 'x64'
+      Platform: 'x64'
+      BuildConfig: RelWithDebInfo
+
+  - task: PythonScript@0
+    displayName: 'Build wheel'
+    inputs:
+      scriptPath: '$(Build.SourcesDirectory)\setup.py'
+      arguments: 'bdist_wheel'
+      workingDirectory: '$(Build.BinariesDirectory)\RelWithDebInfo\RelWithDebInfo'
+
+  - script: |
+     mklink  /D /J $(Build.BinariesDirectory)\RelWithDebInfo\models $(Build.BinariesDirectory)\models
+     DIR dist\ /S /B > wheel_filename_file
+     set /p WHEEL_FILENAME=<wheel_filename_file
+     del wheel_filename_file
+     python.exe -m pip install -q --upgrade %WHEEL_FILENAME%
+     set PATH=$(Build.BinariesDirectory)\RelWithDebInfo\RelWithDebInfo;%PATH%
+     python $(Build.SourcesDirectory)\tools\ci_build\build.py --config RelWithDebInfo --use_binskim_compliant_compile_flags --build_dir $(Build.BinariesDirectory) --skip_submodule_sync --build_shared_lib --cmake_generator "Visual Studio 17 2022" --build_wheel --enable_onnx_tests --use_tensorrt --tensorrt_home="$(Agent.TempDirectory)\${{ variables.win_trt_folder }}" --cuda_home="$(Agent.TempDirectory)\v${{ parameters.CudaVersion }}" --cmake_extra_defines CMAKE_CUDA_ARCHITECTURES=86 --enable_cuda_minimal_build
+
+    workingDirectory: '$(Build.BinariesDirectory)\RelWithDebInfo\RelWithDebInfo'
+    displayName: 'Run tests'
diff --git a/tools/ci_build/github/linux/build_tensorrt_ci.sh b/tools/ci_build/github/linux/build_tensorrt_ci.sh
index 4f9900301c812..ccf7a6f4ea630 100755
--- a/tools/ci_build/github/linux/build_tensorrt_ci.sh
+++ b/tools/ci_build/github/linux/build_tensorrt_ci.sh
@@ -28,7 +28,7 @@ for arg in "$@"; do
     --cuda_minimal=ON)
       # Replace onnxruntime_BUILD_UNIT_TESTS=ON with OFF
       BUILD_ARGS=("${BUILD_ARGS[@]/onnxruntime_BUILD_UNIT_TESTS=ON/onnxruntime_BUILD_UNIT_TESTS=OFF}")
-      BUILD_ARGS+=("onnxruntime_CUDA_MINIMAL=ON")
+      BUILD_ARGS+=("--enable_cuda_minimal_build")
       BUILD_ARGS+=("--skip_tests")
       ;;
   esac