diff --git a/MdePkg/Include/Base.h b/MdePkg/Include/Base.h
index 42f240b0a9..a25cdb7939 100644
--- a/MdePkg/Include/Base.h
+++ b/MdePkg/Include/Base.h
@@ -667,9 +667,7 @@ typedef __builtin_va_list VA_LIST;
 // VA macros for Visual Studio
 // This comes from the VS header:
 //   Microsoft Visual Studio\2017\Enterprise\VC\Tools\MSVC\<version>\include\vadefs.h
-// Do not use when building host-based unit tests as these definitions conflict with those
-// used in original header file.
-#elif defined (_MSC_VER) && !defined (HOST_UNIT_TEST_BUILD)
+#elif defined (_MSC_VER)
 
 //
 // Microsoft compilers