diff --git a/.github/workflows/ci-mmdevice-mmcore.yml b/.github/workflows/ci-mmdevice-mmcore.yml
new file mode 100644
index 000000000..bcc16bb02
--- /dev/null
+++ b/.github/workflows/ci-mmdevice-mmcore.yml
@@ -0,0 +1,67 @@
+name: MMDevice/MMCore experimental Meson build & tests
+
+on:
+  pull_request:
+    paths:
+      - MMDevice/**
+      - MMCore/**
+  push:
+    branches:
+      - main
+    paths:
+      - MMDevice/**
+      - MMCore/**
+
+concurrency:
+  group: ${{ github.workflow }}-${{ github.ref }}
+  cancel-in-progress: true
+
+jobs:
+  test:
+    strategy:
+      fail-fast: false
+      matrix:
+        os:
+          - windows
+          - macos
+          - ubuntu
+        include:
+          - os: windows
+            runner: windows-2019
+            cxx: cl
+          - os: macos
+            runner: macos-11
+            cxx: clang++
+          - os: ubuntu
+            runner: ubuntu-22.04
+            cxx: g++
+    name: ${{ matrix.runner }}-${{ matrix.cxx }}
+    runs-on: ${{ matrix.runner }}
+    env:
+      CXX: ${{ matrix.cxx }}
+    steps:
+      - uses: actions/checkout@v4
+      - uses: actions/setup-python@v5
+        with:
+          python-version: '3.11'
+      - name: Install tools
+        run: |
+          python -m pip install --upgrade pip meson ninja
+      - uses: ilammy/msvc-dev-cmd@v1
+        with:
+          vsversion: '2019'
+      - name: Build and test MMDevice
+        run: |
+          cd MMDevice
+          meson setup builddir --buildtype debug
+          meson test -C builddir --print-errorlogs
+      - name: Prepare MMCore source
+        shell: bash
+        run: |
+          git clean -dxf
+          cp -R MMDevice MMCore/subprojects
+      - name: Build and test MMCore
+        run: |
+          cd MMCore
+          meson setup builddir --buildtype debug
+          meson test -C builddir --print-errorlogs