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version question about meryl #42

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bucongfan opened this issue Apr 7, 2024 · 1 comment
Open

version question about meryl #42

bucongfan opened this issue Apr 7, 2024 · 1 comment

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@bucongfan
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Hi,

Thank you for this awesome software!

During the kmer calling process, I noticed that different versions of Meryl take significantly different amounts of time. Version 1.3.1 is almost three times faster than the version I installed in 2020 using conda, which is version 1.7 showed by --version. However, when using the same dataset, I found that the size of the database differs, even though it generates the same kmer count (verified by using to_hist_for_plotting.sh, which shows the total count is the same).

I'm curious, are there any significant differences between the versions, or are they generally compatible?

I also noticed that the Meryl databases created by different versions seem to have the same structure. Can I use these db, even if they were built with different versions of Meryl?

@bucongfan
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I noticed the compatibility of different Meryl versions you mentioned regarding Canu 1.8. If incompatible db are used, will the current version of Meryl throw an error directly?

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