diff --git a/client/src/components/History/CurrentHistory/HistoryCounter.vue b/client/src/components/History/CurrentHistory/HistoryCounter.vue
index df3f0a1d0e0f..98efa0bf11b8 100644
--- a/client/src/components/History/CurrentHistory/HistoryCounter.vue
+++ b/client/src/components/History/CurrentHistory/HistoryCounter.vue
@@ -12,6 +12,7 @@ import { useRouter } from "vue-router/composables";
 import type { HistorySummary } from "@/api";
 import { HistoryFilters } from "@/components/History/HistoryFilters.js";
 import { useConfig } from "@/composables/config";
+import { useStorageLocationConfiguration } from "@/composables/storageLocation";
 import { useUserStore } from "@/stores/userStore";
 
 import { useDetailedHistory } from "./usesDetailedHistory";
@@ -19,6 +20,8 @@ import { useDetailedHistory } from "./usesDetailedHistory";
 import PreferredStorePopover from "./PreferredStorePopover.vue";
 import SelectPreferredStore from "./SelectPreferredStore.vue";
 
+const { isOnlyPreference } = useStorageLocationConfiguration();
+
 library.add(faDatabase, faEyeSlash, faHdd, faMapMarker, faSync, faTrash);
 
 const props = withDefaults(
@@ -54,6 +57,14 @@ const historyPreferredObjectStoreId = ref(props.history.preferred_object_store_i
 
 const niceHistorySize = computed(() => prettyBytes(historySize.value));
 
+const storageLocationTitle = computed(() => {
+    if (isOnlyPreference.value) {
+        return "History Preferred Storage Location";
+    } else {
+        return "History Storage Location";
+    }
+});
+
 function onDashboard() {
     router.push({ name: "HistoryOverviewInAnalysis", params: { historyId: props.history.id } });
 }
@@ -206,7 +217,7 @@ onMounted(() => {
 
             <BModal
                 v-model="showPreferredObjectStoreModal"
-                title="History Preferred Storage Location"
+                :title="storageLocationTitle"
                 modal-class="history-preferred-object-store-modal"
                 title-tag="h3"
                 size="sm"
diff --git a/client/src/components/History/CurrentHistory/PreferredStorePopover.vue b/client/src/components/History/CurrentHistory/PreferredStorePopover.vue
index b69b2c4008ed..5dba88d7b62c 100644
--- a/client/src/components/History/CurrentHistory/PreferredStorePopover.vue
+++ b/client/src/components/History/CurrentHistory/PreferredStorePopover.vue
@@ -2,8 +2,12 @@
 import { BPopover } from "bootstrap-vue";
 import { computed } from "vue";
 
+import { useStorageLocationConfiguration } from "@/composables/storageLocation";
+
 import ShowSelectedObjectStore from "@/components/ObjectStore/ShowSelectedObjectStore.vue";
 
+const { isOnlyPreference } = useStorageLocationConfiguration();
+
 interface Props {
     historyId: string;
     historyPreferredObjectStoreId?: string;
@@ -19,28 +23,40 @@ const preferredObjectStoreId = computed(() => {
     }
     return id;
 });
+
+const title = computed(() => {
+    if (isOnlyPreference.value) {
+        return "Preferred Storage Location";
+    } else {
+        return "Storage Location";
+    }
+});
 </script>
 
 <template>
     <BPopover :target="`history-storage-${historyId}`" triggers="hover" placement="bottomleft" boundary="window">
-        <template v-slot:title>Preferred Storage Location</template>
+        <template v-slot:title>{{ title }}</template>
         <div class="popover-wide">
+            <p>
+                <b
+                    >This option only affects new datasets created in this history. Existing history datasets will
+                    remain at their current storage location.</b
+                >
+            </p>
+
             <p v-if="historyPreferredObjectStoreId" class="history-preferred-object-store-inherited">
                 This storage location has been set at the history level.
             </p>
             <p v-else class="history-preferred-object-store-not-inherited">
-                This storage location has been inherited from your user preferences (set in User -> Preferences ->
-                Preferred Storage Location). If that option is updated, this history will target that new default.
+                This storage location has been inherited from your user preferences (set in
+                <router-link to="/user">User -> Preferences</router-link> -> {{ title }}). If that option is updated,
+                this history will target that new default.
             </p>
 
             <ShowSelectedObjectStore
                 v-if="preferredObjectStoreId"
                 :preferred-object-store-id="preferredObjectStoreId"
                 for-what="Galaxy will default to storing this history's datasets in " />
-
-            <div v-localize>
-                Change preferred storage location by clicking on the storage button in the history panel.
-            </div>
         </div>
     </BPopover>
 </template>
diff --git a/client/src/components/ObjectStore/SelectObjectStore.vue b/client/src/components/ObjectStore/SelectObjectStore.vue
index def41a60ff4d..1aa6287a6a07 100644
--- a/client/src/components/ObjectStore/SelectObjectStore.vue
+++ b/client/src/components/ObjectStore/SelectObjectStore.vue
@@ -3,6 +3,7 @@ import { storeToRefs } from "pinia";
 import { computed, ref } from "vue";
 
 import { ConcreteObjectStoreModel } from "@/api";
+import { useStorageLocationConfiguration } from "@/composables/storageLocation";
 import { useObjectStoreStore } from "@/stores/objectStoreStore";
 
 import ObjectStoreSelectButton from "./ObjectStoreSelectButton.vue";
@@ -25,6 +26,7 @@ const props = withDefaults(defineProps<SelectObjectStoreProps>(), {
 
 const store = useObjectStoreStore();
 const { isLoading, loadErrorMessage, selectableObjectStores } = storeToRefs(store);
+const { isOnlyPreference } = useStorageLocationConfiguration();
 
 const loadingObjectStoreInfoMessage = ref("Loading storage location information");
 const whyIsSelectionPreferredText = ref(`
@@ -64,7 +66,7 @@ async function handleSubmit(preferredObjectStore: ConcreteObjectStoreModel | nul
             <b-alert v-if="error" variant="danger" class="object-store-selection-error" show>
                 {{ error }}
             </b-alert>
-            <b-row>
+            <b-row align-h="center">
                 <b-col cols="7">
                     <b-button-group vertical size="lg" style="width: 100%">
                         <b-button
@@ -85,7 +87,7 @@ async function handleSubmit(preferredObjectStore: ConcreteObjectStoreModel | nul
                             @click="handleSubmit(objectStore)" />
                     </b-button-group>
                 </b-col>
-                <b-col cols="5">
+                <b-col v-if="isOnlyPreference" cols="5">
                     <p v-localize style="float: right">
                         {{ whyIsSelectionPreferredText }}
                     </p>
diff --git a/client/src/components/ObjectStore/showTargetPopoverMixin.js b/client/src/components/ObjectStore/showTargetPopoverMixin.js
index 66c68f4bfd5e..61f19c279871 100644
--- a/client/src/components/ObjectStore/showTargetPopoverMixin.js
+++ b/client/src/components/ObjectStore/showTargetPopoverMixin.js
@@ -1,3 +1,7 @@
+import { mapState } from "pinia";
+
+import { useConfigStore } from "@/stores/configurationStore";
+
 import ShowSelectedObjectStore from "./ShowSelectedObjectStore";
 
 export default {
@@ -11,8 +15,16 @@ export default {
         },
     },
     computed: {
+        ...mapState(useConfigStore, ["config"]),
+        preferredOrEmptyString() {
+            if (this.config?.object_store_always_respect_user_selection) {
+                return "";
+            } else {
+                return "Preferred";
+            }
+        },
         title() {
-            return this.l(`Preferred Target Storage Location ${this.titleSuffix || ""}`);
+            return this.l(`${this.preferredOrEmptyString} Target Storage Location ${this.titleSuffix || ""}`);
         },
     },
 };
diff --git a/client/src/components/Tool/ToolCard.vue b/client/src/components/Tool/ToolCard.vue
index f1df26492a1a..d28e4d46ad96 100644
--- a/client/src/components/Tool/ToolCard.vue
+++ b/client/src/components/Tool/ToolCard.vue
@@ -7,6 +7,7 @@ import { getAppRoot } from "onload/loadConfig";
 import { storeToRefs } from "pinia";
 import { computed, ref, watch } from "vue";
 
+import { useStorageLocationConfiguration } from "@/composables/storageLocation";
 import { useConfigStore } from "@/stores/configurationStore";
 import { useUserStore } from "@/stores/userStore";
 
@@ -83,12 +84,21 @@ function onSetError(e) {
     errorText.value = e;
 }
 
+const { isOnlyPreference } = useStorageLocationConfiguration();
 const { currentUser, isAnonymous } = storeToRefs(useUserStore());
 const { isLoaded: isConfigLoaded, config } = storeToRefs(useConfigStore());
 const hasUser = computed(() => !isAnonymous.value);
 const versions = computed(() => props.options.versions);
 const showVersions = computed(() => props.options.versions?.length > 1);
 
+const storageLocationModalTitle = computed(() => {
+    if (isOnlyPreference.value) {
+        return "Tool Execution Preferred Storage Location";
+    } else {
+        return "Tool Execution Storage Location";
+    }
+});
+
 const root = computed(() => getAppRoot());
 const showPreferredObjectStoreModal = ref(false);
 const toolPreferredObjectStoreId = ref(props.preferredObjectStoreId);
@@ -148,7 +158,7 @@ const showHelpForum = computed(() => isConfigLoaded.value && config.value.enable
                         </ToolTargetPreferredObjectStorePopover>
                         <b-modal
                             v-model="showPreferredObjectStoreModal"
-                            title="Tool Execution Preferred Storage Location"
+                            :title="storageLocationModalTitle"
                             modal-class="tool-preferred-object-store-modal"
                             title-tag="h3"
                             size="sm"
diff --git a/client/src/components/Tool/ToolTargetPreferredObjectStorePopover.vue b/client/src/components/Tool/ToolTargetPreferredObjectStorePopover.vue
index a88e5214335d..26dc9b790b7f 100644
--- a/client/src/components/Tool/ToolTargetPreferredObjectStorePopover.vue
+++ b/client/src/components/Tool/ToolTargetPreferredObjectStorePopover.vue
@@ -3,8 +3,9 @@
         <template v-slot:title>{{ title }}</template>
         <div class="popover-wide">
             <p v-if="toolPreferredObjectStoreId">
-                Preferred storage location has been set at the tool level, by default history or user preferences will
-                be used and if those are not set Galaxy will pick an administrator-configured default.
+                The {{ preferredOrEmptyString }} storage location has been set at the tool level, by default history or
+                user preferences will be used and if those are not set Galaxy will pick an administrator-configured
+                default.
             </p>
             <ShowSelectedObjectStore
                 v-if="toolPreferredObjectStoreId"
@@ -15,7 +16,8 @@
                 No selection has been made for this tool execution. Defaults from history, user, or Galaxy will be used.
             </div>
             <div v-localize>
-                Change preferred storage location by clicking on the storage button in the tool header.
+                Change {{ preferredOrEmptyString }} storage location by clicking on the storage button in the tool
+                header.
             </div>
         </div>
     </b-popover>
diff --git a/client/src/components/User/UserPreferredObjectStore.vue b/client/src/components/User/UserPreferredObjectStore.vue
index e2c056ddae66..c51ab8b8b60f 100644
--- a/client/src/components/User/UserPreferredObjectStore.vue
+++ b/client/src/components/User/UserPreferredObjectStore.vue
@@ -7,17 +7,17 @@
                 v-b-modal.modal-select-preferred-object-store
                 class="preferred-storage"
                 href="javascript:void(0)"
-                ><b v-localize>Preferred Storage Location</b></a
+                ><b v-localize>{{ title }}</b></a
             >
             <div v-localize class="form-text text-muted">
-                Select a preferred storage location for the outputs of new jobs.
+                Select a {{ preferredOrEmptyString }} storage location for the outputs of new jobs.
             </div>
             <BModal
                 id="modal-select-preferred-object-store"
                 ref="modal"
                 v-model="showModal"
                 centered
-                title="Preferred Storage Location"
+                :title="title"
                 :title-tag="titleTag"
                 hide-footer
                 static
@@ -40,10 +40,13 @@
 import axios from "axios";
 import { BModal, BRow, VBModal } from "bootstrap-vue";
 import SelectObjectStore from "components/ObjectStore/SelectObjectStore";
+import { mapState } from "pinia";
 import { prependPath } from "utils/redirect";
 import { errorMessageAsString } from "utils/simple-error";
 import Vue from "vue";
 
+import { useConfigStore } from "@/stores/configurationStore";
+
 Vue.use(VBModal);
 
 export default {
@@ -76,6 +79,19 @@ export default {
                 "Selecting this will reset Galaxy to default behaviors configured by your Galaxy administrator.",
         };
     },
+    computed: {
+        ...mapState(useConfigStore, ["config"]),
+        preferredOrEmptyString() {
+            if (this.config?.object_store_always_respect_user_selection) {
+                return "";
+            } else {
+                return "Preferred";
+            }
+        },
+        title() {
+            return `${this.preferredOrEmptyString} Storage Location`;
+        },
+    },
     methods: {
         resetModal() {},
         async handleSubmit(preferredObjectStoreId) {
diff --git a/client/src/components/Workflow/Run/WorkflowStorageConfiguration.test.js b/client/src/components/Workflow/Run/WorkflowStorageConfiguration.test.js
index 02ee504ddeed..876578e709c0 100644
--- a/client/src/components/Workflow/Run/WorkflowStorageConfiguration.test.js
+++ b/client/src/components/Workflow/Run/WorkflowStorageConfiguration.test.js
@@ -1,3 +1,4 @@
+import { createTestingPinia } from "@pinia/testing";
 import { mount } from "@vue/test-utils";
 import { findViaNavigation, getLocalVue } from "tests/jest/helpers";
 import { ROOT_COMPONENT } from "utils/navigation";
@@ -18,6 +19,7 @@ describe("WorkflowStorageConfiguration.vue", () => {
         wrapper = mount(WorkflowStorageConfiguration, {
             propsData,
             localVue,
+            pinia: createTestingPinia(),
         });
     }
 
diff --git a/client/src/components/Workflow/Run/WorkflowStorageConfiguration.vue b/client/src/components/Workflow/Run/WorkflowStorageConfiguration.vue
index d6d9b03ea557..d67dc2b5a191 100644
--- a/client/src/components/Workflow/Run/WorkflowStorageConfiguration.vue
+++ b/client/src/components/Workflow/Run/WorkflowStorageConfiguration.vue
@@ -12,11 +12,7 @@
             :title-suffix="suffixPrimary"
             :invocation-preferred-object-store-id="selectedObjectStoreId">
         </WorkflowTargetPreferredObjectStorePopover>
-        <b-modal
-            v-model="showPreferredObjectStoreModal"
-            title="Invocation Preferred Storage Location"
-            v-bind="modalProps"
-            hide-footer>
+        <b-modal v-model="showPreferredObjectStoreModal" :title="primaryModalTitle" v-bind="modalProps" hide-footer>
             <WorkflowSelectPreferredObjectStore
                 :invocation-preferred-object-store-id="selectedObjectStoreId"
                 @updated="onUpdate" />
@@ -37,7 +33,7 @@
         </WorkflowTargetPreferredObjectStorePopover>
         <b-modal
             v-model="showIntermediatePreferredObjectStoreModal"
-            title="Invocation Preferred Storage Location (Intermediate Datasets)"
+            :title="intermediateModalTitle"
             v-bind="modalProps"
             hide-footer>
             <WorkflowSelectPreferredObjectStore
@@ -48,6 +44,10 @@
 </template>
 
 <script>
+import { mapState } from "pinia";
+
+import { useConfigStore } from "@/stores/configurationStore";
+
 import WorkflowSelectPreferredObjectStore from "./WorkflowSelectPreferredObjectStore";
 import WorkflowTargetPreferredObjectStorePopover from "./WorkflowTargetPreferredObjectStorePopover";
 
@@ -79,6 +79,20 @@ export default {
         };
     },
     computed: {
+        ...mapState(useConfigStore, ["config"]),
+        preferredOrEmptyString() {
+            if (this.config?.object_store_always_respect_user_selection) {
+                return "";
+            } else {
+                return "Preferred";
+            }
+        },
+        primaryModalTitle() {
+            return `Invocation ${this.preferredOrEmptyString} Storage Location`;
+        },
+        intermediateModalTitle() {
+            return `Invocation {{ preferredOrEmptyString }} Storage Location (Intermediate Datasets)`;
+        },
         suffixPrimary() {
             if (this.splitObjectStore) {
                 return ` (Workflow Output Datasets)`;
diff --git a/client/src/components/Workflow/Run/WorkflowTargetPreferredObjectStorePopover.vue b/client/src/components/Workflow/Run/WorkflowTargetPreferredObjectStorePopover.vue
index 989689d55a99..ba9bccf13a36 100644
--- a/client/src/components/Workflow/Run/WorkflowTargetPreferredObjectStorePopover.vue
+++ b/client/src/components/Workflow/Run/WorkflowTargetPreferredObjectStorePopover.vue
@@ -9,11 +9,12 @@
                 for-what="Galaxy will default to storing this tool run's output in">
             </ShowSelectedObjectStore>
             <div v-else>
-                No selection has been made for this worklfow invocation. Defaults from history, user, or Galaxy will be
+                No selection has been made for this workflow invocation. Defaults from history, user, or Galaxy will be
                 used.
             </div>
             <div v-localize>
-                Change preferred storage location by clicking on the storage button in the worklfow run header.
+                Change {{ preferredOrEmptyString }} storage location by clicking on the storage button in the worklfow
+                run header.
             </div>
         </div>
     </b-popover>
diff --git a/client/src/composables/storageLocation.ts b/client/src/composables/storageLocation.ts
new file mode 100644
index 000000000000..056ef8ef0b4a
--- /dev/null
+++ b/client/src/composables/storageLocation.ts
@@ -0,0 +1,15 @@
+import { computed } from "vue";
+
+import { useConfig } from "./config";
+
+export function useStorageLocationConfiguration() {
+    const { config } = useConfig();
+
+    const isOnlyPreference = computed(() => {
+        return !config.value || !config.value?.object_store_always_respect_user_selection;
+    });
+
+    return {
+        isOnlyPreference,
+    };
+}
diff --git a/doc/source/admin/galaxy_options.rst b/doc/source/admin/galaxy_options.rst
index 342933fe168b..2100c81f8cae 100644
--- a/doc/source/admin/galaxy_options.rst
+++ b/doc/source/admin/galaxy_options.rst
@@ -1521,6 +1521,20 @@
 :Type: int
 
 
+~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+``object_store_always_respect_user_selection``
+~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+
+:Description:
+    Set this to true to indicate in the UI that a user's object store
+    selection isn't simply a "preference" that job destinations often
+    respect but in fact will always be respected. This should be set
+    to true to simplify the UI as long as job destinations never
+    override 'object_store_id's for a jobs.
+:Default: ``false``
+:Type: bool
+
+
 ~~~~~~~~~~~~~~~~~~~~~~~~~
 ``object_store_store_by``
 ~~~~~~~~~~~~~~~~~~~~~~~~~
diff --git a/lib/galaxy/config/schemas/config_schema.yml b/lib/galaxy/config/schemas/config_schema.yml
index 823780a856f2..ea25af4fc4c4 100644
--- a/lib/galaxy/config/schemas/config_schema.yml
+++ b/lib/galaxy/config/schemas/config_schema.yml
@@ -1094,6 +1094,16 @@ mapping:
           Default cache size for caching object stores if cache not configured for
           that object store entry.
 
+      object_store_always_respect_user_selection:
+        type: bool
+        default: false
+        required: false
+        desc: |
+          Set this to true to indicate in the UI that a user's object store selection
+          isn't simply a "preference" that job destinations often respect but in fact
+          will always be respected. This should be set to true to simplify the UI as
+          long as job destinations never override 'object_store_id's for a jobs.
+
       object_store_store_by:
         type: str
         required: false
diff --git a/lib/galaxy/managers/configuration.py b/lib/galaxy/managers/configuration.py
index bb010dfd909d..14348c06742b 100644
--- a/lib/galaxy/managers/configuration.py
+++ b/lib/galaxy/managers/configuration.py
@@ -213,6 +213,7 @@ def _config_is_truthy(item, key, **context):
             ),
             "object_store_allows_id_selection": lambda item, key, **context: object_store.object_store_allows_id_selection(),
             "object_store_ids_allowing_selection": lambda item, key, **context: object_store.object_store_ids_allowing_selection(),
+            "object_store_always_respect_user_selection": _use_config,
             "user_activation_on": _use_config,
             "user_library_import_dir_available": lambda item, key, **context: bool(item.get("user_library_import_dir")),
             "welcome_directory": _use_config,