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NC_001526.4.gff3
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##sequence-region NC_001526.4 1 7906
##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=333760
NC_001526.4 RefSeq region 1 7906 . + . ID=NC_001526.4:1..7906;Dbxref=taxon:333760;Is_circular=true;gbkey=Src;genome=genomic;mol_type=genomic DNA
NC_001526.4 RefSeq gene 1 2756 . + . ID=gene-HpV16gp5;Dbxref=GeneID:1489076;Name=E1^E4;gbkey=Gene;gene=E1^E4;gene_biotype=protein_coding;locus_tag=HpV16gp5
NC_001526.4 RefSeq CDS 1 16 . + 0 ID=cds-YP_009268708.1;Parent=gene-HpV16gp5;Dbxref=Genbank:YP_009268708.1,GeneID:1489076;Name=YP_009268708.1;Note=Spliced. E1^E4. Contributes to the replication of the viral plasmid genome as a nuclear plasmid in basal cells. It is a multifunctional protein and contributes to different processes in both the early and late stages of the virus life cycle.;experiment=EXISTENCE:;gbkey=CDS;gene=E1^E4;product=cell cycle modulating protein E1^E4;protein_id=YP_009268708.1
NC_001526.4 RefSeq CDS 2494 2756 . + 2 ID=cds-YP_009268708.1;Parent=gene-HpV16gp5;Dbxref=Genbank:YP_009268708.1,GeneID:1489076;Name=YP_009268708.1;Note=Spliced. E1^E4. Contributes to the replication of the viral plasmid genome as a nuclear plasmid in basal cells. It is a multifunctional protein and contributes to different processes in both the early and late stages of the virus life cycle.;experiment=EXISTENCE:;gbkey=CDS;gene=E1^E4;product=cell cycle modulating protein E1^E4;protein_id=YP_009268708.1
NC_001526.4 RefSeq gene 1 1950 . + . ID=gene-HpV16gp3;Dbxref=GeneID:1489075;Name=E1;gbkey=Gene;gene=E1;gene_biotype=protein_coding;locus_tag=HpV16gp3
NC_001526.4 RefSeq CDS 1 1950 . + 0 ID=cds-NP_041327.2;Parent=gene-HpV16gp3;Dbxref=Genbank:NP_041327.2,GeneID:1489075;Name=NP_041327.2;experiment=EXISTENCE:;gbkey=CDS;gene=E1;product=replication protein E1;protein_id=NP_041327.2
NC_001526.4 RefSeq sequence_difference 275 275 . + . ID=id-HpV16gp3;Dbxref=GeneID:1489075;Note=Inserted G was absent in original clone (Seedorf et al.%2C 1985). Restores E1 ORF.';gbkey=misc_difference;gene=E1
NC_001526.4 RefSeq gene 1892 2989 . + . ID=gene-HpV16gp4;Dbxref=GeneID:1489080;Name=E2;gbkey=Gene;gene=E2;gene_biotype=protein_coding;locus_tag=HpV16gp4
NC_001526.4 RefSeq CDS 1892 2989 . + 0 ID=cds-NP_041328.1;Parent=gene-HpV16gp4;Dbxref=Genbank:NP_041328.1,GeneID:1489080;Name=NP_041328.1;Note=E2. Plays a role in the initiation of viral DNA replication. Forms E1-E2 dimer with replication protein E1. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.;gbkey=CDS;gene=E2;product=regulatory protein E2;protein_id=NP_041328.1
NC_001526.4 RefSeq sequence_difference 2062 2062 . + . ID=id-HpV16gp4;Dbxref=GeneID:1489080;Note=replaced G with A;gbkey=misc_difference;gene=E2
NC_001526.4 RefSeq gene 2986 3237 . + . ID=gene-HpV16gp6;Dbxref=GeneID:1489077;Name=E5;gbkey=Gene;gene=E5;gene_biotype=protein_coding;locus_tag=HpV16gp6
NC_001526.4 RefSeq CDS 2986 3237 . + 0 ID=cds-NP_041330.2;Parent=gene-HpV16gp6;Dbxref=Genbank:NP_041330.2,GeneID:1489077;Name=NP_041330.2;Note=E5. Oncoprotein. Contributes to cell transformation. Produces polyploid cells by endoreplication.;experiment=EXISTENCE:;gbkey=CDS;gene=E5;product=transforming protein E5;protein_id=NP_041330.2
NC_001526.4 RefSeq sequence_difference 3043 3043 . + . ID=id-HpV16gp6;Dbxref=GeneID:1489077;Note=Inserted T was absent in the original sequence. Restores E5 ORF.;gbkey=misc_difference;gene=E5
NC_001526.4 RefSeq polyA_signal_sequence 3351 3356 . + . ID=id-NC_001526.4:3351..3356;Note=putative;gbkey=regulatory;regulatory_class=polyA_signal_sequence
NC_001526.4 RefSeq gene 3373 4794 . + . ID=gene-HpV16gp7;Dbxref=GeneID:1489081;Name=L2;gbkey=Gene;gene=L2;gene_biotype=protein_coding;locus_tag=HpV16gp7
NC_001526.4 RefSeq CDS 3373 4794 . + 0 ID=cds-NP_041331.2;Parent=gene-HpV16gp7;Dbxref=Genbank:NP_041331.2,GeneID:1489081;Name=NP_041331.2;Note=L2. Forms an icosahedral capsid. Plays an essential role in virus assembly by recruiting viral components to PML bodies%2C the proposed sites of virus morphogenesis.;experiment=EXISTENCE:;gbkey=CDS;gene=L2;product=minor capsid protein L2;protein_id=NP_041331.2
NC_001526.4 RefSeq sequence_difference 3501 3501 . + . ID=id-HpV16gp7;Dbxref=GeneID:1489081;Note=A in the original sequence is changed to T.;gbkey=misc_difference;gene=L2
NC_001526.4 RefSeq TATA_box 3427 3433 . + . ID=id-HpV16gp7-2;Dbxref=GeneID:1489081;gbkey=regulatory;gene=L2;regulatory_class=TATA_box
NC_001526.4 RefSeq gene 4775 6292 . + . ID=gene-HpV16gp8;Dbxref=GeneID:1489082;Name=L1;gbkey=Gene;gene=L1;gene_biotype=protein_coding;locus_tag=HpV16gp8
NC_001526.4 RefSeq CDS 4775 6292 . + 0 ID=cds-NP_041332.2;Parent=gene-HpV16gp8;Dbxref=Genbank:NP_041332.2,GeneID:1489082;Name=NP_041332.2;experiment=EXISTENCE:;gbkey=CDS;gene=L1;product=major capsid protein L1;protein_id=NP_041332.2
NC_001526.4 RefSeq sequence_difference 5378 5378 . + . ID=id-HpV16gp8;Dbxref=GeneID:1489082;Note=C in original clone replaced wth G;gbkey=misc_difference;gene=L1
NC_001526.4 RefSeq sequence_difference 6039 6041 . + . ID=id-HpV16gp8-2;Dbxref=GeneID:1489082;Note=inserted CAT absent from original sequence;gbkey=misc_difference;gene=L1
NC_001526.4 RefSeq sequence_difference 6088 6088 . + . ID=id-HpV16gp8-3;Dbxref=GeneID:1489082;Note=GAT in original sequence deleted;gbkey=misc_difference;gene=L1
NC_001526.4 RefSeq sequence_feature 6293 7124 . + . ID=id-NC_001526.4:6293..7124;Note=Upstream regulatory region (URR). Contains DNA-protein binding motifs. Involved in replication. Synonims: long control region (LCR)%2C noncoding region (NCR).;function=URR;gbkey=misc_feature
NC_001526.4 RefSeq polyA_signal_sequence 6398 6403 . + . ID=id-NC_001526.4:6398..6403;gbkey=regulatory;regulatory_class=polyA_signal_sequence
NC_001526.4 RefSeq sequence_difference 6570 6570 . + . ID=id-NC_001526.4:6570..6570;Note=GC in original sequence change to CGG;gbkey=misc_difference
NC_001526.4 RefSeq sequence_feature 6589 6600 . + . ID=id-NC_001526.4:6589..6600;Note=E2BS;function=E2 binding site;gbkey=misc_feature
NC_001526.4 RefSeq sequence_feature 6996 7007 . + . ID=id-NC_001526.4:6996..7007;function=E2 binding site;gbkey=misc_feature
NC_001526.4 RefSeq sequence_difference 6997 6997 . + . ID=id-NC_001526.4:6997..6997;Note=A in original sequence was deleted;gbkey=misc_difference
NC_001526.4 RefSeq TATA_box 7059 7065 . + . ID=id-NC_001526.4:7059..7065;gbkey=regulatory;regulatory_class=TATA_box
NC_001526.4 RefSeq sequence_feature 7077 7088 . + . ID=id-NC_001526.4:7077..7088;Note=E2BS;function=E2 binding site;gbkey=misc_feature
NC_001526.4 RefSeq sequence_feature 7092 7103 . + . ID=id-NC_001526.4:7092..7103;Note=E2BS;function=E2 binding site;gbkey=misc_feature
NC_001526.4 RefSeq TATA_box 7107 7113 . + . ID=id-NC_001526.4:7107..7113;gbkey=regulatory;regulatory_class=TATA_box
NC_001526.4 RefSeq gene 7125 7601 . + . ID=gene-HpV16gp1;Dbxref=GeneID:1489078;Name=E6;gbkey=Gene;gene=E6;gene_biotype=protein_coding;locus_tag=HpV16gp1
NC_001526.4 RefSeq CDS 7125 7601 . + 0 ID=cds-NP_041325.1;Parent=gene-HpV16gp1;Dbxref=Genbank:NP_041325.1,GeneID:1489078;Name=NP_041325.1;Note=Oncoprotein. It has long been recognized as a potent oncogene and is intimately associated with the events that result in the malignant conversion of virally infected cells.;experiment=EXISTENCE:;gbkey=CDS;gene=E6;product=transforming protein E6;protein_id=NP_041325.1
NC_001526.4 RefSeq CDS 7125 7268 . + 0 ID=cds-YP_009268707.1;Parent=gene-HpV16gp1;Dbxref=Genbank:YP_009268707.1,GeneID:1489078;Name=YP_009268707.1;Note=Spliced. E6*. Function is not known yet.;experiment=EXISTENCE:;gbkey=CDS;gene=E6;product=protein E6*;protein_id=YP_009268707.1
NC_001526.4 RefSeq CDS 7451 7459 . + 0 ID=cds-YP_009268707.1;Parent=gene-HpV16gp1;Dbxref=Genbank:YP_009268707.1,GeneID:1489078;Name=YP_009268707.1;Note=Spliced. E6*. Function is not known yet.;experiment=EXISTENCE:;gbkey=CDS;gene=E6;product=protein E6*;protein_id=YP_009268707.1
NC_001526.4 RefSeq gene 7604 7900 . + . ID=gene-HpV16gp2;Dbxref=GeneID:1489079;Name=E7;gbkey=Gene;gene=E7;gene_biotype=protein_coding;locus_tag=HpV16gp2
NC_001526.4 RefSeq CDS 7604 7900 . + 0 ID=cds-NP_041326.1;Parent=gene-HpV16gp2;Dbxref=Genbank:NP_041326.1,GeneID:1489079;Name=NP_041326.1;Note=E7. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.;experiment=EXISTENCE:;gbkey=CDS;gene=E7;product=transforming protein E7;protein_id=NP_041326.1