diff --git a/x-pack/plugins/osquery/cypress/e2e/all/alerts_cases.cy.ts b/x-pack/plugins/osquery/cypress/e2e/all/alerts_cases.cy.ts
index c4a570ad277b4..f898886506fd0 100644
--- a/x-pack/plugins/osquery/cypress/e2e/all/alerts_cases.cy.ts
+++ b/x-pack/plugins/osquery/cypress/e2e/all/alerts_cases.cy.ts
@@ -23,11 +23,13 @@ import {
   submitQuery,
   viewRecentCaseAndCheckResults,
 } from '../../tasks/live_query';
-import { generateRandomStringName, interceptCaseId } from '../../tasks/integrations';
+import {
+  closeAlertsStepTourIfVisible,
+  generateRandomStringName,
+  interceptCaseId,
+} from '../../tasks/integrations';
 
-// FLAKY: https://github.com/elastic/kibana/issues/170960
-// Failing: See https://github.com/elastic/kibana/issues/170960
-describe.skip('Alert Event Details - Cases', { tags: ['@ess', '@serverless'] }, () => {
+describe('Alert Event Details - Cases', { tags: ['@ess', '@serverless'] }, () => {
   let ruleId: string;
   let packId: string;
   let packName: string;
@@ -68,6 +70,7 @@ describe.skip('Alert Event Details - Cases', { tags: ['@ess', '@serverless'] },
     it('runs osquery against alert and creates a new case', () => {
       const [caseName, caseDescription] = generateRandomStringName(2);
       cy.getBySel('expand-event').first().click();
+      closeAlertsStepTourIfVisible();
       cy.getBySel('take-action-dropdown-btn').click();
       cy.getBySel('osquery-action-item').click();
       cy.contains(/^\d+ agen(t|ts) selected/);
@@ -103,6 +106,7 @@ describe.skip('Alert Event Details - Cases', { tags: ['@ess', '@serverless'] },
 
     it('sees osquery results from last action and add to a case', () => {
       cy.getBySel('expand-event').first().click();
+      closeAlertsStepTourIfVisible();
       cy.getBySel('securitySolutionFlyoutResponseSectionHeader').click();
       cy.getBySel('securitySolutionFlyoutResponseButton').click();
       cy.getBySel('responseActionsViewWrapper').should('exist');
diff --git a/x-pack/plugins/osquery/cypress/e2e/all/alerts_linked_apps.cy.ts b/x-pack/plugins/osquery/cypress/e2e/all/alerts_linked_apps.cy.ts
index 5cb29315e59a2..45921be4cbc2e 100644
--- a/x-pack/plugins/osquery/cypress/e2e/all/alerts_linked_apps.cy.ts
+++ b/x-pack/plugins/osquery/cypress/e2e/all/alerts_linked_apps.cy.ts
@@ -15,12 +15,14 @@ import {
   selectAllAgents,
   submitQuery,
 } from '../../tasks/live_query';
-import { closeModalIfVisible, closeToastIfVisible } from '../../tasks/integrations';
+import {
+  closeAlertsStepTourIfVisible,
+  closeModalIfVisible,
+  closeToastIfVisible,
+} from '../../tasks/integrations';
 import { RESULTS_TABLE, RESULTS_TABLE_BUTTON } from '../../screens/live_query';
 
-// FLAKY: https://github.com/elastic/kibana/issues/180852
-// Failing: See https://github.com/elastic/kibana/issues/180852
-describe.skip(
+describe(
   'Alert Event Details',
   {
     tags: ['@ess', '@serverless'],
@@ -71,6 +73,7 @@ describe.skip(
     it('should be able to run live query and add to timeline', () => {
       const TIMELINE_NAME = 'Untitled timeline';
       cy.getBySel('expand-event').first().click();
+      closeAlertsStepTourIfVisible();
       cy.getBySel('take-action-dropdown-btn').click();
       cy.getBySel('osquery-action-item').click();
       cy.contains('1 agent selected.');
diff --git a/x-pack/plugins/osquery/cypress/e2e/all/alerts_multiple_agents.cy.ts b/x-pack/plugins/osquery/cypress/e2e/all/alerts_multiple_agents.cy.ts
index 7b644b8269a9c..f8241c52bda28 100644
--- a/x-pack/plugins/osquery/cypress/e2e/all/alerts_multiple_agents.cy.ts
+++ b/x-pack/plugins/osquery/cypress/e2e/all/alerts_multiple_agents.cy.ts
@@ -14,9 +14,9 @@ import {
   takeOsqueryActionWithParams,
 } from '../../tasks/live_query';
 import { OSQUERY_FLYOUT_BODY_EDITOR } from '../../screens/live_query';
+import { closeAlertsStepTourIfVisible } from '../../tasks/integrations';
 
-// Failing: See https://github.com/elastic/kibana/issues/180851
-describe.skip(
+describe(
   'Alert Event Details - dynamic params',
   {
     tags: ['@ess', '@serverless'],
@@ -43,6 +43,7 @@ describe.skip(
 
     it('should substitute parameters in investigation guide', () => {
       cy.getBySel('expand-event').first().click();
+      closeAlertsStepTourIfVisible();
       cy.getBySel('securitySolutionFlyoutInvestigationGuideButton').click();
       // Flakes at times if the button is only clicked once
       cy.contains('Get processes').should('be.visible').dblclick({ force: true });
diff --git a/x-pack/plugins/osquery/cypress/e2e/roles/alert_test.cy.ts b/x-pack/plugins/osquery/cypress/e2e/roles/alert_test.cy.ts
index caeb174884cad..5ca5775247caf 100644
--- a/x-pack/plugins/osquery/cypress/e2e/roles/alert_test.cy.ts
+++ b/x-pack/plugins/osquery/cypress/e2e/roles/alert_test.cy.ts
@@ -9,10 +9,9 @@ import { initializeDataViews } from '../../tasks/login';
 import { checkResults, clickRuleName, submitQuery } from '../../tasks/live_query';
 import { loadRule, cleanupRule } from '../../tasks/api_fixtures';
 import { ServerlessRoleName } from '../../support/roles';
+import { closeAlertsStepTourIfVisible } from '../../tasks/integrations';
 
-// FLAKY: https://github.com/elastic/kibana/issues/180853
-// Failing: See https://github.com/elastic/kibana/issues/180853
-describe.skip('Alert Test', { tags: ['@ess'] }, () => {
+describe('Alert Test', { tags: ['@ess'] }, () => {
   let ruleName: string;
   let ruleId: string;
 
@@ -31,6 +30,7 @@ describe.skip('Alert Test', { tags: ['@ess'] }, () => {
       cy.visit('/app/security/rules');
       clickRuleName(ruleName);
       cy.getBySel('expand-event').first().click({ force: true });
+      closeAlertsStepTourIfVisible();
 
       cy.wait(500);
       cy.getBySel('securitySolutionFlyoutInvestigationGuideButton').click();
diff --git a/x-pack/plugins/osquery/cypress/screens/integrations.ts b/x-pack/plugins/osquery/cypress/screens/integrations.ts
index 5c3b7408e3047..250bce8d3f131 100644
--- a/x-pack/plugins/osquery/cypress/screens/integrations.ts
+++ b/x-pack/plugins/osquery/cypress/screens/integrations.ts
@@ -18,6 +18,10 @@ export const CONFIRM_MODAL_BTN_SEL = `[data-test-subj=${CONFIRM_MODAL_BTN}]`;
 export const TOAST_CLOSE_BTN = 'toastCloseButton';
 export const TOAST_CLOSE_BTN_SEL = `[data-test-subj=${TOAST_CLOSE_BTN}]`;
 
+export const SECURITY_SOLUTION_FLYOUT_TOUR = 'securitySolutionFlyoutTour-1';
+
+export const SECURITY_SOLUTION_FLYOUT_TOUR_SEL = `[data-test-subj=${SECURITY_SOLUTION_FLYOUT_TOUR}]`;
+
 export const SETTINGS_TAB = 'tab-settings';
 export const POLICIES_TAB = 'tab-policies';
 
diff --git a/x-pack/plugins/osquery/cypress/tasks/integrations.ts b/x-pack/plugins/osquery/cypress/tasks/integrations.ts
index e4c38854a5faf..e87b9228ad7ef 100644
--- a/x-pack/plugins/osquery/cypress/tasks/integrations.ts
+++ b/x-pack/plugins/osquery/cypress/tasks/integrations.ts
@@ -16,6 +16,7 @@ import {
   DATA_COLLECTION_SETUP_STEP,
   DATE_PICKER_ABSOLUTE_TAB,
   DATE_PICKER_ABSOLUTE_TAB_SEL,
+  SECURITY_SOLUTION_FLYOUT_TOUR_SEL,
   TOAST_CLOSE_BTN,
   TOAST_CLOSE_BTN_SEL,
 } from '../screens/integrations';
@@ -135,6 +136,16 @@ export function closeToastIfVisible() {
   });
 }
 
+export function closeAlertsStepTourIfVisible() {
+  cy.get(SECURITY_SOLUTION_FLYOUT_TOUR_SEL).then(($el) => {
+    if ($el.length > 0) {
+      cy.wrap($el).within(() => {
+        cy.contains('Exit').click();
+      });
+    }
+  });
+}
+
 export const deleteIntegrations = async (integrationName: string) => {
   const ids: string[] = [];
   cy.contains(integrationName)