diff --git a/Dockerfile b/Dockerfile
index 7b9745aba..2f3531282 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -3,19 +3,9 @@ FROM ruby:2.4
 # Cleanup expired Let's Encrypt CA (Sept 30, 2021)
 RUN sed -i '/^mozilla\/DST_Root_CA_X3/s/^/!/' /etc/ca-certificates.conf && update-ca-certificates -f
 
-RUN \
-  apt-get update && \
-  apt-get install -y \
-    cron \
-    # wkhtmltopdf dependencies \
-    xfonts-75dpi \
-    xfonts-base \
-  && apt-get clean && rm -rf /var/lib/apt/lists/* /tmp/* /var/tmp/*
-
-# wkhtmltopdf
-RUN curl -L https://github.com/wkhtmltopdf/packaging/releases/download/0.12.6-1/wkhtmltox_0.12.6-1.stretch_amd64.deb --output wkhtmltopdf.deb && \
-    dpkg -i wkhtmltopdf.deb && \
-    rm -f wkhtmltopdf.deb
+RUN apt-get update && \
+    apt-get install -y cron && \
+    apt-get clean && rm -rf /var/lib/apt/lists/* /tmp/* /var/tmp/*
 
 # Create a user for the web app.
 RUN addgroup --gid 9999 app && \
diff --git a/Dockerfile-dev b/Dockerfile-dev
index ca7aef1b1..cc4afcccb 100644
--- a/Dockerfile-dev
+++ b/Dockerfile-dev
@@ -1,5 +1,12 @@
 FROM ruby:2.4
 
+# Cleanup expired Let's Encrypt CA (Sept 30, 2021)
+RUN sed -i '/^mozilla\/DST_Root_CA_X3/s/^/!/' /etc/ca-certificates.conf && update-ca-certificates -f
+
+RUN apt-get update && \
+    apt-get install -y cron default-mysql-client && \
+    apt-get clean && rm -rf /var/lib/apt/lists/* /tmp/* /var/tmp/*
+
 # ENV POIROT_STDOUT true
 # ENV POIROT_SUPPRESS_RAILS_LOG true
 # ENV NNDD_VERSION "cdx-0.11-pre7"
@@ -8,36 +15,3 @@ FROM ruby:2.4
 # RUN \
 #   mkdir -p /app/public/ && \
 #   curl -L https://github.com/instedd/notifiable-diseases/releases/download/$NNDD_VERSION/nndd.tar.gz | tar -xzv -C /app/public/
-
-ENV LOCAL_SHARE "/usr/local/share"
-
-# Cleanup expired Let's Encrypt CA (Sept 30, 2021)
-RUN sed -i '/^mozilla\/DST_Root_CA_X3/s/^/!/' /etc/ca-certificates.conf && update-ca-certificates -f
-
-RUN \
-  apt-get update && \
-  apt-get install -y \
-    build-essential \
-    chrpath \
-    cron \
-    libssl-dev \
-    libxft-dev \
-    libfreetype6 \
-    libfreetype6-dev \
-    libfontconfig1 \
-    libfontconfig1-dev \
-    # wkhtmltopdf dependencies \
-    xfonts-75dpi \
-    xfonts-base \
-    imagemagick \
-    ghostscript \
-    libgs-dev \
-    default-mysql-client \
-  && apt-get clean && rm -rf /var/lib/apt/lists/* /tmp/* /var/tmp/*
-
-ARG TARGETARCH
-
-# wkhtmltopdf
-RUN curl -L https://github.com/wkhtmltopdf/packaging/releases/download/0.12.6-1/wkhtmltox_0.12.6-1.buster_${TARGETARCH}.deb --output wkhtmltopdf.deb && \
-    dpkg -i wkhtmltopdf.deb && \
-    rm -f wkhtmltopdf.deb
diff --git a/Gemfile b/Gemfile
index c329177b9..c7452a85e 100644
--- a/Gemfile
+++ b/Gemfile
@@ -31,7 +31,8 @@ gem 'csv_builder', '~> 2.1'
 gem 'haml-rails', '~> 0.9'
 gem 'jbuilder', '~> 2.5'
 gem 'view_components', git: 'https://github.com/manastech/rails-view_components.git', branch: 'master'
-gem 'wicked_pdf', '~> 2.1'
+gem 'prawn'
+gem 'prawn-svg'
 
 # Authentication
 # gem 'bcrypt-ruby', '~> 3.1.2'
diff --git a/Gemfile.lock b/Gemfile.lock
index 770628389..755563a90 100644
--- a/Gemfile.lock
+++ b/Gemfile.lock
@@ -375,6 +375,14 @@ GEM
       parallel
     paranoia (2.4.3)
       activerecord (>= 4.0, < 6.2)
+    pdf-core (0.7.0)
+    prawn (2.2.2)
+      pdf-core (~> 0.7.0)
+      ttfunk (~> 1.5)
+    prawn-svg (0.32.0)
+      css_parser (~> 1.6)
+      prawn (>= 0.11.1, < 3)
+      rexml (~> 3.2)
     premailer (1.12.1)
       addressable
       css_parser (>= 1.6.0)
@@ -544,6 +552,7 @@ GEM
     tilt (2.0.11)
     timecop (0.9.6)
     trollop (2.9.10)
+    ttfunk (1.6.2.1)
     turbolinks (2.5.4)
       coffee-rails
     tzinfo (1.2.10)
@@ -570,8 +579,6 @@ GEM
     websocket-extensions (0.1.5)
     whenever (1.0.0)
       chronic (>= 0.6.3)
-    wicked_pdf (2.6.3)
-      activesupport
     xpath (3.2.0)
       nokogiri (~> 1.8)
 
@@ -629,6 +636,8 @@ DEPENDENCIES
   parallel_tests (~> 3.5.1)
   paranoia (< 2.5.0)
   poirot_rails!
+  prawn
+  prawn-svg
   premailer-rails (< 1.10)
   pry-byebug (< 3.10.0)
   pry-rescue
@@ -666,7 +675,6 @@ DEPENDENCIES
   web-console (< 4.0)
   webmock (~> 2.3.1)
   whenever (~> 1.0)
-  wicked_pdf (~> 2.1)
 
 BUNDLED WITH
    1.17.3
diff --git a/app/assets/fonts/Roboto/LICENSE.txt b/app/assets/fonts/Roboto/LICENSE.txt
new file mode 100644
index 000000000..75b52484e
--- /dev/null
+++ b/app/assets/fonts/Roboto/LICENSE.txt
@@ -0,0 +1,202 @@
+
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+                           Version 2.0, January 2004
+                        http://www.apache.org/licenses/
+
+   TERMS AND CONDITIONS FOR USE, REPRODUCTION, AND DISTRIBUTION
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+      by You to the Licensor shall be under the terms and conditions of
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+      whether in tort (including negligence), contract, or otherwise,
+      unless required by applicable law (such as deliberate and grossly
+      negligent acts) or agreed to in writing, shall any Contributor be
+      liable to You for damages, including any direct, indirect, special,
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+      Work (including but not limited to damages for loss of goodwill,
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+      on Your own behalf and on Your sole responsibility, not on behalf
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+
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+
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+   distributed under the License is distributed on an "AS IS" BASIS,
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diff --git a/app/assets/fonts/Roboto/RobotoMono-Bold.ttf b/app/assets/fonts/Roboto/RobotoMono-Bold.ttf
new file mode 100644
index 000000000..8eff26c1e
Binary files /dev/null and b/app/assets/fonts/Roboto/RobotoMono-Bold.ttf differ
diff --git a/app/assets/fonts/Roboto/RobotoMono-Regular.ttf b/app/assets/fonts/Roboto/RobotoMono-Regular.ttf
new file mode 100644
index 000000000..d9371a1bd
Binary files /dev/null and b/app/assets/fonts/Roboto/RobotoMono-Regular.ttf differ
diff --git a/app/assets/stylesheets/_barcode_card.scss b/app/assets/stylesheets/_barcode_card.scss
index dfedee380..55c9b9a7a 100644
--- a/app/assets/stylesheets/_barcode_card.scss
+++ b/app/assets/stylesheets/_barcode_card.scss
@@ -66,60 +66,6 @@
   }
 }
 
-// Print Barcode style
-
-.barcode-card-print {
-  page-break-after: always;
-  break-after: page;
-
-  height: 100%;
-  width: 100%;
-
-  font-family: 'Roboto Mono', monospace;
-
-  background: $white;
-  margin: 1px;
-  padding: 3px;
-
-  .barcode {
-    margin: auto; // center barcode
-    margin-top: 0;
-    margin-bottom: 0;
-    width: 40%;
-  }
-
-  .code {
-    font-size: 9px;
-    margin: -1px;
-    padding: 0 1px;
-
-    .uuid {
-      margin: 0px;
-      text-align: center;
-    }
-  }
-
-  .logo {
-    @include flexbox();
-    flex-direction: row;
-    align-items: center;
-
-    font-size: 7px;
-    padding: 0 1px;
-    margin-top: 1px;
-    width: 100%;
-
-    .label {
-      margin-left: 3px;
-    }
-
-    img {
-      width: 15px;
-      height: auto;
-    }
-  }
-}
-
 // INVENTORY
 
 .inventory-button {
diff --git a/app/assets/stylesheets/pdf.scss b/app/assets/stylesheets/pdf.scss
deleted file mode 100644
index 60300b248..000000000
--- a/app/assets/stylesheets/pdf.scss
+++ /dev/null
@@ -1,5 +0,0 @@
-@import "variables";
-@import "mixins";
-@import "reset";
-@import "layout";
-@import "barcode_card";
diff --git a/app/controllers/boxes_controller.rb b/app/controllers/boxes_controller.rb
index 24f253c04..a3e749853 100644
--- a/app/controllers/boxes_controller.rb
+++ b/app/controllers/boxes_controller.rb
@@ -38,17 +38,10 @@ def inventory
   def print
     return unless authorize_resource(@box, READ_BOX)
 
-    render pdf: "cdx_box_#{@box.uuid}",
-      template: "boxes/print.pdf",
-      layout: "layouts/pdf.html",
-      locals: {
-        box: @box,
-        samples: @box.samples.preload(:batch, :sample_identifiers).map { |s| SamplePresenter.new(s, request.format) },
-      },
-      margin: { top: 0, bottom: 0, left: 0, right: 0 },
-      page_width: "1in",
-      page_height: "1in",
-      show_as_html: params.key?("debug")
+    send_data BoxLabelPdf.render(@box, @box.samples.preload(:batch, :sample_identifiers)),
+      filename: "cdx_box_#{@box.uuid}",
+      type: "application/pdf",
+      disposition: "inline"
   end
 
   def new
diff --git a/app/controllers/samples_controller.rb b/app/controllers/samples_controller.rb
index 6a10d6e48..88446ab66 100644
--- a/app/controllers/samples_controller.rb
+++ b/app/controllers/samples_controller.rb
@@ -121,31 +121,23 @@ def create
   end
 
   def print
-    @sample = Sample.find(params[:id])
-    return unless authorize_resource(@sample, READ_SAMPLE)
-
-    render pdf: "cdx_sample_#{@sample.uuid}",
-      template: "samples/barcode.pdf",
-      layout: "layouts/pdf.html",
-      locals: { :sample => SamplePresenter.new(@sample, request.format) },
-      margin: { top: 0, bottom: 0, left: 0, right: 0 },
-      page_width: "1in",
-      page_height: "1in",
-      show_as_html: params.key?("debug")
+    sample = Sample.find(params[:id])
+    return unless authorize_resource(sample, READ_SAMPLE)
+
+    send_data SampleLabelPdf.render(sample),
+      filename: "cdx_sample_#{sample.uuid}.pdf",
+      type: "application/pdf",
+      disposition: "inline"
   end
 
   def bulk_print
     samples = Sample.where(id: params[:sample_ids])
     return unless authorize_resources(samples, READ_SAMPLE)
 
-    render pdf: "cdx_samples_#{samples.size}_#{DateTime.now.strftime("%Y%m%d-%H%M")}",
-      template: "samples/bulk_print.pdf",
-      layout: "layouts/pdf.html",
-      locals: { samples: samples.preload(:sample_identifiers).map { |s| SamplePresenter.new(s, request.format) } },
-      margin: { top: 0, bottom: 0, left: 0, right: 0 },
-      page_width: "1in",
-      page_height: "1in",
-      show_as_html: params.key?("debug")
+    send_data SamplesLabelPdf.render(samples.preload(:box, :sample_identifiers)),
+      filename: "cdx_samples_#{samples.size}_#{DateTime.now.strftime("%Y%m%d-%H%M")}",
+      type: "application/pdf",
+      disposition: "inline"
   end
 
   def edit
diff --git a/app/documents/base_pdf.rb b/app/documents/base_pdf.rb
new file mode 100644
index 000000000..94aacffbd
--- /dev/null
+++ b/app/documents/base_pdf.rb
@@ -0,0 +1,20 @@
+class BasePdf
+  include Prawn::View
+
+  def self.render(*args)
+    view = new(*args)
+    view.setup
+    view.template
+    view.render
+  end
+
+  def assets_path
+    @assets_path ||= Rails.root.join("app/assets")
+  end
+
+  def setup
+  end
+
+  def template
+  end
+end
diff --git a/app/documents/box_label_pdf.rb b/app/documents/box_label_pdf.rb
new file mode 100644
index 000000000..a79d1c1d9
--- /dev/null
+++ b/app/documents/box_label_pdf.rb
@@ -0,0 +1,24 @@
+class BoxLabelPdf < SamplesLabelPdf
+  def initialize(box, samples)
+    @box = box
+    super(samples)
+  end
+
+  def template
+    render_uuid(@box.uuid)
+    render_box_details
+    render_cdx_logo
+
+    start_new_page
+    super
+  end
+
+  protected
+
+  def render_box_details
+    text_lines [
+      @box.institution.name.truncate(22),
+      "#{@box.purpose} (#{@samples.size} samples)",
+    ]
+  end
+end
diff --git a/app/documents/label_pdf.rb b/app/documents/label_pdf.rb
new file mode 100644
index 000000000..6a0b7cc01
--- /dev/null
+++ b/app/documents/label_pdf.rb
@@ -0,0 +1,65 @@
+class LabelPdf < BasePdf
+  def document
+    @document ||= Prawn::Document.new(
+      top_margin: 1.8,
+      left_margin: 2.4,
+      right_margin: 2,
+      bottom_margin: 0,
+      page_size: [72, 72], # 1in == 72pt
+      print_scaling: :none
+    )
+  end
+
+  def setup
+    font_families.update("RobotoMono" => {
+      normal: assets_path.join("fonts/Roboto/RobotoMono-Regular.ttf"),
+      bold: assets_path.join("fonts/Roboto/RobotoMono-Bold.ttf"),
+    })
+    font "RobotoMono"
+    font_size 5.3
+    default_leading 0
+  end
+
+  protected
+
+  def render_uuid(uuid)
+    svg qrcode_svg(uuid), width: 27.4, height: 27.4, position: :center, enable_web_requests: false
+    move_down 1.6
+    text_line uuid, align: :center, leading: 0.2
+    move_up 0.6
+  end
+
+  def qrcode_svg(value)
+    barcode = Barby::QrCode.new(value, level: :m)
+    outputter = Barby::SvgOutputter.new(barcode)
+    outputter.xdim = 2
+    outputter.margin = 0
+    outputter.to_svg
+  end
+
+  def render_sample_details(sample)
+    text_lines [
+      "I.N. #{sample.isolate_name}".truncate(22),
+      "I.M. #{sample.inactivation_method}".truncate(22),
+      "P.D. #{sample.date_produced.strftime("%m/%d/%Y")}",
+    ], leading: -0.5
+  end
+
+  def render_cdx_logo
+    bounding_box [0.6, 7], width: bounds.right do
+      image assets_path.join("images/cdx-logo-bw.png"), width: 8.9, height: 4.1
+      move_up 4.5
+      text "https://cdx.io", indent_paragraphs: 10.8, character_spacing: -0.07, size: 4.1
+    end
+  end
+
+  def text_lines(lines, leading: -0.5, **options)
+    lines.each_with_index do |line, index|
+      text_line line, leading: leading, **options
+    end
+  end
+
+  def text_line(line, **options)
+    text line, character_spacing: -0.2, **options
+  end
+end
diff --git a/app/documents/sample_label_pdf.rb b/app/documents/sample_label_pdf.rb
new file mode 100644
index 000000000..72949aca9
--- /dev/null
+++ b/app/documents/sample_label_pdf.rb
@@ -0,0 +1,11 @@
+class SampleLabelPdf < LabelPdf
+  def initialize(sample)
+    @sample = SamplePresenter.new(sample, Mime::Type.lookup("application/pdf"))
+  end
+
+  def template
+    render_uuid(@sample.uuid)
+    render_sample_details(@sample)
+    render_cdx_logo
+  end
+end
diff --git a/app/documents/samples_label_pdf.rb b/app/documents/samples_label_pdf.rb
new file mode 100644
index 000000000..f5190d630
--- /dev/null
+++ b/app/documents/samples_label_pdf.rb
@@ -0,0 +1,15 @@
+class SamplesLabelPdf < LabelPdf
+  def initialize(samples)
+    format = Mime::Type.lookup("application/pdf")
+    @samples = samples.map { |sample| SamplePresenter.new(sample, format)  }
+  end
+
+  def template
+    @samples.each_with_index do |sample, index|
+      start_new_page unless index == 0
+      render_uuid(sample.uuid)
+      render_sample_details(sample)
+      render_cdx_logo
+    end
+  end
+end
diff --git a/app/helpers/barcode_helper.rb b/app/helpers/barcode_helper.rb
index 777dff50f..3ab899621 100644
--- a/app/helpers/barcode_helper.rb
+++ b/app/helpers/barcode_helper.rb
@@ -14,7 +14,7 @@ def barcode(code)
 
   def image_barcode(code)
     barcode = Barby::Code93.new(code)
-    file = Tempfile.new(['barcode', '.png'])
+    file = Tempfile.new(['barcode', '.png'], encoding: "BINARY")
     outputter = Barby::PngOutputter.new(barcode)
     outputter.xdim = 2
     file.write outputter.to_png
diff --git a/app/views/boxes/barcode.pdf.haml b/app/views/boxes/barcode.pdf.haml
deleted file mode 100644
index 0b467bddc..000000000
--- a/app/views/boxes/barcode.pdf.haml
+++ /dev/null
@@ -1,14 +0,0 @@
-.barcode-card-print
-  .barcode-content
-    .barcode
-      = image_tag barcode_img_data_url(box.uuid)
-    .code
-      .uuid
-        #{box.uuid}
-    .code
-      #{(box.institution.name).truncate(22)}
-    .code
-      #{box.purpose} (#{box.samples.count} samples)
-    .logo
-      = image_tag wicked_pdf_asset_base64('cdx-logo-bw.png')
-      .label https://cdx.io
diff --git a/app/views/boxes/print.pdf.haml b/app/views/boxes/print.pdf.haml
deleted file mode 100644
index 1f8324638..000000000
--- a/app/views/boxes/print.pdf.haml
+++ /dev/null
@@ -1,4 +0,0 @@
-= render template: "boxes/barcode", locals: { box: box }
-
-- samples.each do |sample|
-  = render template: "samples/barcode", locals: { sample: sample }
diff --git a/app/views/layouts/pdf.html.haml b/app/views/layouts/pdf.html.haml
deleted file mode 100644
index 89de282c6..000000000
--- a/app/views/layouts/pdf.html.haml
+++ /dev/null
@@ -1,8 +0,0 @@
-!!!
-%html
-  %head
-    %title Connected Diagnostics Platform
-    = stylesheet_link_tag wicked_pdf_asset_base64("pdf")
-    = wicked_pdf_stylesheet_link_tag "https://fonts.googleapis.com/css2?family=Roboto+Mono:wght@400;700&display=swap"
-  %body
-    = yield
diff --git a/app/views/samples/barcode.pdf.haml b/app/views/samples/barcode.pdf.haml
deleted file mode 100644
index a5c5e848c..000000000
--- a/app/views/samples/barcode.pdf.haml
+++ /dev/null
@@ -1,18 +0,0 @@
-.barcode-card-print
-  .barcode-content
-    -# .title
-    -#   = sample.institution
-    .barcode
-      = image_tag barcode_img_data_url(sample.uuid)
-    .code
-      .uuid
-        #{sample.uuid}
-    .code
-      I.N. #{sample.isolate_name}
-    .code
-      I.M. #{sample.inactivation_method}
-    .code
-      P.D. #{sample.date_produced_description}
-    .logo
-      = image_tag wicked_pdf_asset_base64('cdx-logo-bw.png')
-      .label https://cdx.io
diff --git a/app/views/samples/bulk_print.pdf.haml b/app/views/samples/bulk_print.pdf.haml
deleted file mode 100644
index 731036c25..000000000
--- a/app/views/samples/bulk_print.pdf.haml
+++ /dev/null
@@ -1,2 +0,0 @@
-- samples.each do |sample|
-  = render template: "samples/barcode.pdf", locals: { sample: sample }
diff --git a/config/application.rb b/config/application.rb
index c6b234bd4..b6c52ec0e 100644
--- a/config/application.rb
+++ b/config/application.rb
@@ -28,7 +28,7 @@ class Application < Rails::Application
       g.assets = false
     end
     config.autoload_paths << Rails.root.join("features", "support", "page_objects")
-    config.autoload_paths += %W(#{config.root}/lib)
+    config.autoload_paths += %W(#{config.root}/documents #{config.root}/lib)
 
     config.assets.precompile += %w( mailer.css )
 
diff --git a/config/initializers/wicked_pdf.rb b/config/initializers/wicked_pdf.rb
deleted file mode 100644
index e7a2d3302..000000000
--- a/config/initializers/wicked_pdf.rb
+++ /dev/null
@@ -1,27 +0,0 @@
-# WickedPDF Global Configuration
-#
-# Use this to set up shared configuration options for your entire application.
-# Any of the configuration options shown here can also be applied to single
-# models by passing arguments to the `render :pdf` call.
-#
-# To learn more, check out the README:
-#
-# https://github.com/mileszs/wicked_pdf/blob/master/README.md
-
-WickedPdf.config = {
-  # Path to the wkhtmltopdf executable: This usually isn't needed if using
-  # one of the wkhtmltopdf-binary family of gems.
-  exe_path: '/usr/local/bin/wkhtmltopdf',
-  #   or
-  # exe_path: Gem.bin_path('wkhtmltopdf-binary', 'wkhtmltopdf')
-
-  # Layout file to be used for all PDFs
-  # (but can be overridden in `render :pdf` calls)
-  # layout: 'pdf.html',
-
-  # Using wkhtmltopdf without an X server can be achieved by enabling the
-  # 'use_xvfb' flag. This will wrap all wkhtmltopdf commands around the
-  # 'xvfb-run' command, in order to simulate an X server.
-  #
-  # use_xvfb: true,
-}