From de3ad8a941671403d8c86a601f4684d1c8e46909 Mon Sep 17 00:00:00 2001 From: Jin Xu Date: Sun, 21 Apr 2024 23:48:35 -0700 Subject: [PATCH] Update README.md --- README.md | 6 +++--- 1 file changed, 3 insertions(+), 3 deletions(-) diff --git a/README.md b/README.md index 4a6e7d4..cb99a93 100644 --- a/README.md +++ b/README.md @@ -11,11 +11,11 @@ - B.S. in Electronic Engineering and Information Science, University of Science and Technology of China, 2002 ## Selected Research Projects -- *Applying Deep Learning to Drug Discovery*: [Our publication in the Journal of Medicinal Chemistry](https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.3c01471) describes a novel small molecule ligand for WDR91 by using affinity-mediated DNA-encoded chemical library selection followed by deep learning. WDRs’unique β-propeller structure makes them attractive targets, but most human WDRs are unexplored compared to other major drug target families. The discovery of a drug-like small molecule and its covalent analog compounds will soon enable researchers to identify a WDR91 drug candidate. -- *Studying secure communication from information theoretic perspective*: [Our publication in IEEE Transactions on Information Theory](https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.3c01471) provided new insights into secure communication over broadcast channels by developing both inner and outer bounds for the rate equivocation region. +- *Applying Deep Learning to Drug Discovery*: [Our publication in the Journal of Medicinal Chemistry](https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.3c01471), for the first time, discovered a novel small molecule ligand for WDR91 by using affinity-mediated DNA-encoded chemical library selection followed by deep learning. WDRs’unique β-propeller structure makes them attractive targets, but most human WDRs are unexplored compared to other major drug target families. The discovery of a drug-like small molecule and its covalent analog compounds will soon enable researchers to identify a WDR91 drug candidate. +- *Studying secure communication from information theoretic perspective*: [Our publication in IEEE Transactions on Information Theory](https://ieeexplore.ieee.org/abstract/document/5238755) provided new insights into secure communication over broadcast channels by developing both inner and outer bounds for the rate equivocation region. -## Mini-projects +## Colabs * [JAX implementation of MinGPT](https://github.com/imxj/imxj.github.io/blob/master/colabs/llms/jax_gpt_dev_gpt.ipynb) * [PubChem and Mols2Grid](https://github.com/imxj/imxj.github.io/tree/master/colabs/small_molecules)