diff --git a/Content.Server/_Impstation/Xenoarchaeology/XenoArtifacts/Effects/Components/ScrambleDNAArtifactComponent.cs b/Content.Server/_Impstation/Xenoarchaeology/XenoArtifacts/Effects/Components/ScrambleDNAArtifactComponent.cs
new file mode 100644
index 00000000000000..114810bf57de86
--- /dev/null
+++ b/Content.Server/_Impstation/Xenoarchaeology/XenoArtifacts/Effects/Components/ScrambleDNAArtifactComponent.cs
@@ -0,0 +1,34 @@
+namespace Content.Server.Xenoarchaeology.XenoArtifacts.Effects.Components;
+
+/// <summary>
+/// Scrambles DNA of some number of people within some range, possibly outside of their species
+/// </summary>
+[RegisterComponent]
+public sealed partial class ScrambleDNAArtifactComponent : Component
+{
+    /// <summary>
+    /// Distance from the artifact find people to scramble DNA
+    /// </summary>
+    [DataField("range"), ViewVariables(VVAccess.ReadWrite)]
+    public float Range = 6f;
+
+    /// <summary>
+    /// Number of people to DNA scramble
+    /// </summary>
+    [DataField("count"), ViewVariables(VVAccess.ReadWrite)]
+    public int Count = 1;
+
+    /// <summary>
+    /// Force scrambling to respect initial species
+    /// </summary>
+    [DataField("withinSpecies"), ViewVariables(VVAccess.ReadWrite)]
+    public bool WithinSpecies = true;
+
+    /// <summary>
+    /// if WithinSpecies is false, what species cannot be rolled
+    /// </summary>
+    [DataField("excludedSpecies"), ViewVariables(VVAccess.ReadWrite)]
+    public HashSet<string>? ExcludedSpecies = null;
+
+
+}
diff --git a/Content.Server/_Impstation/Xenoarchaeology/XenoArtifacts/Effects/Systems/KnockdownArtifactSystem.cs b/Content.Server/_Impstation/Xenoarchaeology/XenoArtifacts/Effects/Systems/KnockdownArtifactSystem.cs
index eba2ef50dff49c..0c7061455df6c8 100644
--- a/Content.Server/_Impstation/Xenoarchaeology/XenoArtifacts/Effects/Systems/KnockdownArtifactSystem.cs
+++ b/Content.Server/_Impstation/Xenoarchaeology/XenoArtifacts/Effects/Systems/KnockdownArtifactSystem.cs
@@ -44,8 +44,6 @@ private void OnActivated(EntityUid uid, KnockdownArtifactComponent component, Ar
                 _stuns.TryParalyze(child, TimeSpan.FromSeconds(component.KnockdownTime), true, status);
             }
 
-
-
         }
         else // knock over only people in range
         {
diff --git a/Content.Server/_Impstation/Xenoarchaeology/XenoArtifacts/Effects/Systems/ScrambleDNAArtifactSystem.cs b/Content.Server/_Impstation/Xenoarchaeology/XenoArtifacts/Effects/Systems/ScrambleDNAArtifactSystem.cs
new file mode 100644
index 00000000000000..7ceee0f6303945
--- /dev/null
+++ b/Content.Server/_Impstation/Xenoarchaeology/XenoArtifacts/Effects/Systems/ScrambleDNAArtifactSystem.cs
@@ -0,0 +1,79 @@
+using Content.Server.Xenoarchaeology.XenoArtifacts.Effects.Components;
+using Content.Server.Xenoarchaeology.XenoArtifacts.Events;
+using Content.Shared.Preferences;
+using Content.Server.Humanoid;
+using System.Linq;
+using Robust.Shared.Random;
+using Content.Shared.Humanoid;
+using Content.Shared.Forensics;
+using Content.Server.Forensics;
+
+
+
+namespace Content.Server.Xenoarchaeology.XenoArtifacts.Effects.Systems;
+
+public sealed class ScrambleDNAArtifactSystem : EntitySystem
+{
+    [Dependency] private readonly EntityLookupSystem _lookup = default!;
+    [Dependency] private readonly IRobustRandom _random = default!;
+    [Dependency] private readonly HumanoidAppearanceSystem _humanoidAppearance = default!;
+    [Dependency] private readonly MetaDataSystem _metaData = default!;
+    [Dependency] private readonly ForensicsSystem _forensicsSystem = default!;
+
+
+
+    /// <inheritdoc/>
+    public override void Initialize()
+    {
+        SubscribeLocalEvent<ScrambleDNAArtifactComponent, ArtifactActivatedEvent>(OnActivated);
+    }
+
+    private void OnActivated(EntityUid uid, ScrambleDNAArtifactComponent component, ArtifactActivatedEvent args)
+    {
+        // Get all entities in range, and the person who activated the artifact even if they are not within range
+        var ents = _lookup.GetEntitiesInRange(uid, component.Range);
+        if (args.Activator != null)
+            ents.Add(args.Activator.Value);
+
+        //Extract the people who can be scrambled
+        var possibleVictims = new List<EntityUid>();
+        foreach (var ent in ents)
+        {
+            if (HasComp<HumanoidAppearanceComponent>(ent))
+                possibleVictims.Add(ent);
+        }
+
+        //Select random targets to scramble DNA
+        var numScrambled = 0;
+        while (numScrambled < component.Count){
+            var targetIndex = _random.Next(0, possibleVictims.Count);
+            var target = possibleVictims.ElementAt(targetIndex);
+            possibleVictims.Remove(target);
+
+            ScrambleTargetDNA(target, component);
+            numScrambled ++;
+        }
+    }
+
+    private void ScrambleTargetDNA(EntityUid target, ScrambleDNAArtifactComponent component)
+    {
+        if (TryComp<HumanoidAppearanceComponent>(target, out var humanoid))
+        {
+            var newProfile = (component.WithinSpecies ? HumanoidCharacterProfile.RandomWithSpecies(humanoid.Species) : HumanoidCharacterProfile.Random(component.ExcludedSpecies));
+            _humanoidAppearance.LoadProfile(target, newProfile, humanoid);
+            _metaData.SetEntityName(target, newProfile.Name);
+            if (TryComp<DnaComponent>(target, out var dna))
+            {
+                dna.DNA = _forensicsSystem.GenerateDNA();
+
+                var ev = new GenerateDnaEvent { Owner = target, DNA = dna.DNA };
+                RaiseLocalEvent(target, ref ev);
+            }
+            if (TryComp<FingerprintComponent>(target, out var fingerprint))
+            {
+                fingerprint.Fingerprint = _forensicsSystem.GenerateFingerprint();
+            }
+        }
+    }
+
+}
diff --git a/Resources/Prototypes/XenoArch/Effects/normal_effects.yml b/Resources/Prototypes/XenoArch/Effects/normal_effects.yml
index 87ded0225ce13e..60f7e32dfdd5ab 100644
--- a/Resources/Prototypes/XenoArch/Effects/normal_effects.yml
+++ b/Resources/Prototypes/XenoArch/Effects/normal_effects.yml
@@ -1081,6 +1081,17 @@
     duration: 10
     count: 1
 
+- type: artifactEffect
+  id: EffectScrambleSingleRare
+  targetDepth: 4
+  effectHint: artifact-effect-hint-polymorph
+  effectProb: 0.01
+  components:
+  - type: ScrambleDNAArtifact
+    range: 4
+    withinSpecies: true
+    count: 1
+
 - type: artifactEffect
   id: EffectSingulo
   targetDepth: 10