Update sodium effect #9
Merged
Conversation
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
different effect size for sbp over/under 140
also tested in a notebook
aflaxman
requested review from
albrja,
hussain-jafari,
patricktnast,
rmudambi and
stevebachmeier
as code owners
albrja
approved these changes
Oct 31, 2024
aflaxman
commented
Nov 5, 2024
| ) # 5.8 (2.5, 9.2) mmHg decrease per 6g/day sodium decrease | ||
| # previously used 5.8 (2.5, 9.2) mmHg decrease per 6g/day sodium decrease for both (doi: 10.1002/14651858.CD004937.pub2 ?) | ||
| mmHg_per_g_sodium_for_low_sbp = ( | ||
| 1.0 # (.5, 1.49) mmHg from https://doi.org/10.1161/CIRCULATIONAHA.120.050371 |
There was a problem hiding this comment.
I would like to include the parameter uncertainty on this. @albrja or anyone, do you have an example of how we have done this before that I can adapt? I used a random seed hack in an old project that would work, but there must be something more standard by now.
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Add this suggestion to a batch that can be applied as a single commit.
This suggestion is invalid because no changes were made to the code.
Suggestions cannot be applied while the pull request is closed.
Suggestions cannot be applied while viewing a subset of changes.
Only one suggestion per line can be applied in a batch.
Add this suggestion to a batch that can be applied as a single commit.
Applying suggestions on deleted lines is not supported.
You must change the existing code in this line in order to create a valid suggestion.
Outdated suggestions cannot be applied.
This suggestion has been applied or marked resolved.
Suggestions cannot be applied from pending reviews.
Suggestions cannot be applied on multi-line comments.
Suggestions cannot be applied while the pull request is queued to merge.
Suggestion cannot be applied right now. Please check back later.
Title: Update sodium effect on SBP to have different slope for SBP above and below 140
Description
Changes and notes
Meta-analysis https://doi.org/10.1161/CIRCULATIONAHA.120.050371 has more detail on how dose-response effect functions and how it is different based on SBP level.Verification and Testing
Cool figure showing how it works when I make everyone eat twice as much salt as in baseline
