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---
layout: about
title: About IQ-TREE
permalink: /about/
---
<div class="container">
<div class="row">
<div class="col-md-6">
<h3>Why IQ-TREE?</h3>
<div class="hline"></div>
<p>
Thanks to the recent advent of next-generation sequencing techniques, the amount of phylogenomic/transcriptomic data have been rapidly accumulated. This extremely facilitates resolving many "deep phylogenetic" questions in the <em>tree of life</em>. At the same time it poses major computational challenges to analyze such <em>big data</em>, where most phylogenetic software <em>cannot</em> handle. Moreover, there is a need to develop more complex probabilistic models to adequately capture realistic aspects of genomic sequence evolution.
</p>
<p>This trends motivated us to develop the IQ-TREE software with a strong emphasis on phylogenomic inference. Our goals are:</p>
<ul>
<li> <strong>Accuracy</strong>: Proposing novel computational methods that perform better than existing approaches.</li>
<li> <strong>Speed</strong>: Allowing fast analysis on big data sets and utilizing high performance computing platforms.</li>
<li> <strong>Flexibility</strong>: Facilitating the inclusion of new (phylogenomic) models and sequence data types.</li>
<li> <strong>Versatility</strong>: Implementing a broad range of commonly-used maximum likelihood analyses.</li>
</ul>
<p>IQ-TREE has been developed since 2011 as open-source software under the <a href="http://www.gnu.org/licenses/licenses.en.html">GNU-GPL license</a>. It is actively maintained by the core development team (see below) and a number of collabrators (see right).</p>
<p>
The name IQ-TREE comes from the fact that it is the successor of <a href="http://www.cibiv.at/software/iqpnni/"><u>IQ</u>PNNI</a> and <a href="http://www.tree-puzzle.de"><u>TREE</u>-PUZZLE</a> software.</p>
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<div class="col-md-6">
<h3>Contact</h3>
<div class="hline"></div>
<p> If you have further questions, feedback, feature requests and bug reports, please sign up (if not done yet) and post a topic to <a href="https://groups.google.com/d/forum/iqtree">IQ-TREE Google group</a>.</p>
<p><em>The average response time is two working days.</em></p>
<!-- <h3>Ongoing collaborations</h3>
<div class="hline"></div>
<h4>Phylogenetic likelihood library</h4>
<p>Further development of the <a href="http://www.libpll.org">phylogenetic likelihood library</a> (<a href="http://dx.doi.org/10.1093/sysbio/syu084">Flouri et al., 2015</a>). In collaboration with <a href="http://sco.h-its.org/exelixis/people.html">Alexandros Stamatakis</a> and <a href="http://sco.h-its.org/exelixis/people.html">Tomas Flouri</a>.</p>
<h4>Ultrafast parsimony bootstrap</h4>
<p>An ultrafast approximation method for parsimony bootstrap. In collaboration with <a href="http://uet.vnu.edu.vn/~vinhls/">Le Sy Vinh</a> and <a href="http://www.cibiv.at/~diep_/">Diep Thi Hoang</a>.</p>
<h4>Polymorphism Models (PoMo)</h4>
<p>Efficient implementation of <a href="http://dx.doi.org/10.1093/sysbio/syv048">polymorphism aware model</a> into IQ-TREE. In collaboration with <a href="http://i122server.vu-wien.ac.at/pop/lab_members/Carolin_Kosiol.html">Carolin Kosiol</a> and <a href="http://i122server.vu-wien.ac.at/pop/lab_members/Dominik_Schrempf.html">Dominik Schrempf.</a></p>
<h4>ModelFinder</h4>
<p>A new model selection procedure based on IQ-TREE code. In collaboration with <a href="http://sydney.edu.au/science/biology/about_us/honorary_staff/jermiin_lars/">Lars Jermiin</a> and <a href="https://scholar.google.com/citations?user=zZT0fKUAAAAJ">Thomas Wong</a>.</p>
<h4>Heterotachy models</h4>
<p>Development of heterotachy models that allows for rate heterogeneity among lineages. In collaboration with <a href="http://www.utas.edu.au/maths-physics/people-old/profiles-mathematics/Barbara-Holland">Barbara Holland</a> and <a href="http://maths.adelaide.edu.au/people/stephen.crotty">Stephen Crotty</a>.</p>
<h4>Non-reversible and Lie Markov models</h4>
<p>In collaboration with <a href="http://www.utas.edu.au/profiles/staff/maths-physics/michael-woodhams">Michael Woodhams</a>, <a href="http://www.utas.edu.au/profiles/staff/maths-physics/jeremy-sumner">Jeremy Sumner</a>, and <a href="http://www.utas.edu.au/profiles/staff/maths-physics/Michael-Charleston">Michael Charleston</a>.</p>
<h4>Approximate mixture models</h4>
<p>In collaboration with <a href="http://rogerlab.biochemistryandmolecularbiology.dal.ca/Huaichun.php">Huaichun Wang</a>, <a href="http://rogerlab.biochemistryandmolecularbiology.dal.ca">Andrew Roger</a>, <a href="http://www.mathstat.dal.ca/~tsusko/">Edward Susko</a>.</p>
-->
<h3>Credits </h3>
<div class="hline"></div>
<p>Some parts of the code were taken from the following packages/libraries: <a href="http://www.libpll.org">Phylogenetic likelihood library</a>, <a href="http://www.tree-puzzle.de">TREE-PUZZLE</a>,
<a href="http://dx.doi.org/10.1093/oxfordjournals.molbev.a025808">BIONJ</a>, <a href="http://dx.doi.org/10.1093/bioinformatics/btg319">Nexus Class Libary</a>, <a href="http://eigen.tuxfamily.org/">Eigen library</a>,
<a href="http://www.sprng.org">SPRNG library</a>, <a href="http://www.zlib.net">Zlib library</a>, gzstream library, <a href="http://www.agner.org/optimize/">vectorclass library</a>, <a href="https://www.gnu.org/software/gsl/">GNU scientific library</a>.</p>
<h3>Fundings</h3>
<div class="hline"></div>
<p>Generous fundings for the IQ-TREE project are provided by the
<a href="http://www.fwf.ac.at">Austrian Science Fund - FWF</a>
(grants I 760-B17 from 2012-2015 and I 2508-B29 from 2016-2019),
<a href="https://www.univie.ac.at">University of Vienna</a>
(Initiativkolleg I059-N from 2011-2014),
<a href="https://www.arc.gov.au">Australian Research Council</a>
Discovery Project (DP200103151),
and <a href="https://chanzuckerberg.com">Chan-Zuckerberg Initiative</a> (EOSS-0000000132).</p>
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