diff --git a/packages/bundler-plugin-core/src/index.ts b/packages/bundler-plugin-core/src/index.ts
index 3dc36c0d..d7f46758 100644
--- a/packages/bundler-plugin-core/src/index.ts
+++ b/packages/bundler-plugin-core/src/index.ts
@@ -183,6 +183,9 @@ export function sentryUnpluginFactory({
       if (bundleSizeOptimizations.excludeReplayShadowDom) {
         replacementValues["__RRWEB_EXCLUDE_SHADOW_DOM__"] = true;
       }
+      if (bundleSizeOptimizations.excludeReplayWorker) {
+        replacementValues["__SENTRY_EXCLUDE_REPLAY_WORKER__"] = true;
+      }
 
       if (Object.keys(replacementValues).length > 0) {
         plugins.push(bundleSizeOptimizationsPlugin(replacementValues));
diff --git a/packages/bundler-plugin-core/src/types.ts b/packages/bundler-plugin-core/src/types.ts
index 15a9ca1d..08325777 100644
--- a/packages/bundler-plugin-core/src/types.ts
+++ b/packages/bundler-plugin-core/src/types.ts
@@ -267,6 +267,13 @@ export interface Options {
      * Note that the success of this depends on tree shaking generally being enabled in your build.
      */
     excludeReplayIframe?: boolean;
+
+    /**
+     * If set to true, the plugin will try to tree-shake Session Replay's Compression Web Worker out.
+     * You should only do this if you manually host a compression worker and configure it in your Replay config via `workerUrl`.
+     * Note that the success of this depends on tree shaking generally being enabled in your build.
+     */
+    excludeReplayWorker?: boolean;
   };
 
   /**
@@ -395,6 +402,7 @@ export interface SentrySDKBuildFlags extends Record<string, boolean | undefined>
   __RRWEB_EXCLUDE_CANVAS__?: boolean;
   __RRWEB_EXCLUDE_IFRAME__?: boolean;
   __RRWEB_EXCLUDE_SHADOW_DOM__?: boolean;
+  __SENTRY_EXCLUDE_REPLAY_WORKER__?: boolean;
 }
 
 type SetCommitsOptions = (AutoSetCommitsOptions | ManualSetCommitsOptions) & {
diff --git a/packages/integration-tests/fixtures/bundle-size-optimizations/bundle-size-optimizations.test.ts b/packages/integration-tests/fixtures/bundle-size-optimizations/bundle-size-optimizations.test.ts
index a12d9f78..fb754943 100644
--- a/packages/integration-tests/fixtures/bundle-size-optimizations/bundle-size-optimizations.test.ts
+++ b/packages/integration-tests/fixtures/bundle-size-optimizations/bundle-size-optimizations.test.ts
@@ -7,7 +7,7 @@ import { testIfNodeMajorVersionIsLessThan18 } from "../../utils/testIf";
 const expectedOutputs: Record<string, Record<string, string>> = {
   esbuild: {
     "bundle1.js": `console.log(1)`,
-    "bundle2.js": `console.log({debug:"b",trace:"b",replayCanvas:"a",replayIframe:"a",replayShadowDom:"a"})`,
+    "bundle2.js": `console.log({debug:"b",trace:"b",replayCanvas:"a",replayIframe:"a",replayShadowDom:"a",replayWorker:"a"})`,
   },
   rollup: {
     "bundle1.js": `console.log(1 );`,
@@ -17,19 +17,20 @@ const expectedOutputs: Record<string, Record<string, string>> = {
   replayCanvas: "a" ,
   replayIframe: "a" ,
   replayShadowDom: "a" ,
+  replayWorker: "a" ,
 });`,
   },
   vite: {
     "bundle1.js": `console.log(1);`,
-    "bundle2.js": `console.log({debug:"b",trace:"b",replayCanvas:"a",replayIframe:"a",replayShadowDom:"a"});`,
+    "bundle2.js": `console.log({debug:"b",trace:"b",replayCanvas:"a",replayIframe:"a",replayShadowDom:"a",replayWorker:"a"})`,
   },
   webpack4: {
     "bundle1.js": `console.log(1)`,
-    "bundle2.js": `console.log({debug:"b",trace:"b",replayCanvas:"a",replayIframe:"a",replayShadowDom:"a"})`,
+    "bundle2.js": `console.log({debug:"b",trace:"b",replayCanvas:"a",replayIframe:"a",replayShadowDom:"a",replayWorker:"a"})`,
   },
   webpack5: {
     "bundle1.js": `console.log(1)`,
-    "bundle2.js": `console.log({debug:"b",trace:"b",replayCanvas:"a",replayIframe:"a",replayShadowDom:"a"});`,
+    "bundle2.js": `console.log({debug:"b",trace:"b",replayCanvas:"a",replayIframe:"a",replayShadowDom:"a",replayWorker:"a"})`,
   },
 };
 
diff --git a/packages/integration-tests/fixtures/bundle-size-optimizations/input/bundle2.js b/packages/integration-tests/fixtures/bundle-size-optimizations/input/bundle2.js
index 436e11bc..e6c49f94 100644
--- a/packages/integration-tests/fixtures/bundle-size-optimizations/input/bundle2.js
+++ b/packages/integration-tests/fixtures/bundle-size-optimizations/input/bundle2.js
@@ -4,4 +4,5 @@ console.log({
   replayCanvas: __RRWEB_EXCLUDE_CANVAS__ ? "a" : "b",
   replayIframe: __RRWEB_EXCLUDE_IFRAME__ ? "a" : "b",
   replayShadowDom: __RRWEB_EXCLUDE_SHADOW_DOM__ ? "a" : "b",
+  replayWorker: __SENTRY_EXCLUDE_REPLAY_WORKER__ ? "a" : "b",
 });
diff --git a/packages/integration-tests/fixtures/bundle-size-optimizations/setup.ts b/packages/integration-tests/fixtures/bundle-size-optimizations/setup.ts
index 74699d2a..8e1fb1dc 100644
--- a/packages/integration-tests/fixtures/bundle-size-optimizations/setup.ts
+++ b/packages/integration-tests/fixtures/bundle-size-optimizations/setup.ts
@@ -20,6 +20,7 @@ createCjsBundles(
       excludeReplayCanvas: true,
       excludeReplayIframe: true,
       excludeReplayShadowDom: true,
+      excludeReplayWorker: true,
     },
   }
 );