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How can I use outputs of HiCPro to predict 3D models? #8

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DontCareYaYa opened this issue Jun 28, 2023 · 1 comment
Open

How can I use outputs of HiCPro to predict 3D models? #8

DontCareYaYa opened this issue Jun 28, 2023 · 1 comment
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enhancement New feature or request

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@DontCareYaYa
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Hello~ This is a wonderful tool for people who are in the field~!

I already have the final outputs of HiCPro (such as .matrix and _abs.bed ), I don't need to run HiCPro again through 3d-genome-builder. So, how can I use 3d-genome-builder to predict the 3D structure of chromatins?

@pierrepo pierrepo added the enhancement New feature or request label Jun 28, 2023
@pierrepo
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Hello @GleeenSIBS
Thanks for your interest in 3DGB.

The workflow is currently fully integrated, meaning it is not possible to plug in already generated files such as matrix files. We designed the workflow this way to ensure solid consistency along the entire procedure, avoiding extra quality check at intermediate steps.
For now, the only possibility is to run the workflow from scratch, starting with FASTQ and genome files.

However, your query is absolutely valid and we will keep it in our backlog.

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