diff --git a/CHANGELOG.md b/CHANGELOG.md
index a3a4842197..e3aa703460 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -29,6 +29,7 @@
 * (block-stm) [#1515](https://github.com/crypto-org-chain/cronos/pull/1515) Improve performance by cache signature verification result between incarnations of same tx.
 * (store) [#1526](https://github.com/crypto-org-chain/cronos/pull/1526) Cache index/filters in rocksdb application.db to reduce ram usage.
 * (store)[#1529](https://github.com/crypto-org-chain/cronos/pull/1529) Enable pinL0FilterAndIndexBlocksInCache.
+* (store)[#1547](https://github.com/crypto-org-chain/cronos/pull/1547) Disable memiavl cache if block-stm is enabled.
 
 ### Bug Fixes
 
diff --git a/app/app.go b/app/app.go
index b4df0fc360..80401cee2e 100644
--- a/app/app.go
+++ b/app/app.go
@@ -382,8 +382,15 @@ func New(
 		app.SetProcessProposal(handler.ProcessProposalHandler())
 	})
 
+	blockSTMEnabled := cast.ToString(appOpts.Get(srvflags.EVMBlockExecutor)) == "block-stm"
+
 	homePath := cast.ToString(appOpts.Get(flags.FlagHome))
-	baseAppOptions = memiavlstore.SetupMemIAVL(logger, homePath, appOpts, false, false, baseAppOptions)
+	var cacheSize int
+	if !blockSTMEnabled {
+		// only enable memiavl cache if block-stm is not enabled, because it's not concurrency-safe.
+		cacheSize = cast.ToInt(appOpts.Get(memiavlstore.FlagCacheSize))
+	}
+	baseAppOptions = memiavlstore.SetupMemIAVL(logger, homePath, appOpts, false, false, cacheSize, baseAppOptions)
 
 	// enable optimistic execution
 	baseAppOptions = append(baseAppOptions, baseapp.SetOptimisticExecution())
@@ -414,8 +421,7 @@ func New(
 
 	app.SetDisableBlockGasMeter(true)
 
-	executor := cast.ToString(appOpts.Get(srvflags.EVMBlockExecutor))
-	if executor == "block-stm" {
+	if blockSTMEnabled {
 		sdk.SetAddrCacheEnabled(false)
 		workers := cast.ToInt(appOpts.Get(srvflags.EVMBlockSTMWorkers))
 		app.SetTxExecutor(evmapp.STMTxExecutor(app.GetStoreKeys(), workers))
diff --git a/store/setup.go b/store/setup.go
index f17cedf6da..ee4bd9f306 100644
--- a/store/setup.go
+++ b/store/setup.go
@@ -26,14 +26,22 @@ const (
 
 // SetupMemIAVL insert the memiavl setter in front of baseapp options, so that
 // the default rootmulti store is replaced by memiavl store,
-func SetupMemIAVL(logger log.Logger, homePath string, appOpts servertypes.AppOptions, sdk46Compact bool, supportExportNonSnapshotVersion bool, baseAppOptions []func(*baseapp.BaseApp)) []func(*baseapp.BaseApp) {
+func SetupMemIAVL(
+	logger log.Logger,
+	homePath string,
+	appOpts servertypes.AppOptions,
+	sdk46Compact bool,
+	supportExportNonSnapshotVersion bool,
+	cacheSize int,
+	baseAppOptions []func(*baseapp.BaseApp),
+) []func(*baseapp.BaseApp) {
 	if cast.ToBool(appOpts.Get(FlagMemIAVL)) {
 		opts := memiavl.Options{
 			AsyncCommitBuffer:   cast.ToInt(appOpts.Get(FlagAsyncCommitBuffer)),
 			ZeroCopy:            cast.ToBool(appOpts.Get(FlagZeroCopy)),
 			SnapshotKeepRecent:  cast.ToUint32(appOpts.Get(FlagSnapshotKeepRecent)),
 			SnapshotInterval:    cast.ToUint32(appOpts.Get(FlagSnapshotInterval)),
-			CacheSize:           cast.ToInt(appOpts.Get(FlagCacheSize)),
+			CacheSize:           cacheSize,
 			SnapshotWriterLimit: cast.ToInt(appOpts.Get(FlagSnapshotWriterLimit)),
 		}