diff --git a/nix/default-s390x.nix b/nix/default-s390x.nix
index dc80f086..3be20a05 100644
--- a/nix/default-s390x.nix
+++ b/nix/default-s390x.nix
@@ -1,6 +1,9 @@
 (import ./nixpkgs.nix {
   crossSystem = {
-    config = "s390x-unknown-linux-gnu";
+    # TODO: Switch back to glibc when
+    # https://github.com/NixOS/nixpkgs/issues/306473
+    # is resolved.
+    config = "s390x-unknown-linux-musl";
   };
   overlays = [ (import ./overlay.nix) ];
 }).callPackage ./derivation.nix
diff --git a/nix/derivation.nix b/nix/derivation.nix
index c857e711..5362f990 100644
--- a/nix/derivation.nix
+++ b/nix/derivation.nix
@@ -1,23 +1,22 @@
-{ pkgs }:
+{ stdenv
+, pkgs
+}:
 with pkgs; stdenv.mkDerivation rec {
   name = "conmon";
   src = ./..;
-  vendorSha256 = null;
+  vendorHash = null;
   doCheck = false;
   enableParallelBuilding = true;
   outputs = [ "out" ];
   nativeBuildInputs = with buildPackages; [
-    bash
     gitMinimal
     pkg-config
-    which
   ];
-  buildInputs = [
-    glib
-    glibc
+  buildInputs = lib.optionals (!stdenv.hostPlatform.isMusl) [
     glibc.static
+  ] ++ [
+    pkgsStatic.glib
     libseccomp
-    pcre2
   ];
   prePatch = ''
     export CFLAGS='-static -pthread'
diff --git a/nix/nixpkgs.json b/nix/nixpkgs.json
index 93b5f999..c7ae2277 100644
--- a/nix/nixpkgs.json
+++ b/nix/nixpkgs.json
@@ -1,10 +1,10 @@
 {
   "url": "https://github.com/nixos/nixpkgs",
-  "rev": "f4f097b65b336b1f4cdf947b7fbe076bd2a69126",
-  "date": "2024-02-28T11:07:01+01:00",
-  "path": "/nix/store/4blmmjaibdghqzk1wa8la3w9afvyldpq-nixpkgs",
-  "sha256": "0r1kbfbh3rbpl4w7rvyxyl3q6nchnmmd6bjwsqbz0gbsrsly7vbg",
-  "hash": "sha256-b+3jqc56PfAX1lwu02q1kFmDB/Xd73w4oXflAZdbM2Q=",
+  "rev": "17d58b30575bb965966d67e8ca1070f9a71cfb41",
+  "date": "2024-04-25T11:03:10+03:00",
+  "path": "/nix/store/01ql69ya47924icr0sm5vclrcl98ryr2-nixpkgs",
+  "sha256": "1szc653551qmd1iqk6lqcnamsr7bdd5qrfimi4r1ma199cblpd14",
+  "hash": "sha256-JLRLF0spqBoyiTW6jEtr62RdlWWYmoljaBWHUkYx7Os=",
   "fetchLFS": false,
   "fetchSubmodules": false,
   "deepClone": false,
diff --git a/nix/overlay.nix b/nix/overlay.nix
index 71349b72..212e0679 100644
--- a/nix/overlay.nix
+++ b/nix/overlay.nix
@@ -4,23 +4,4 @@ self: super:
     doCheck = false;
     dontDisableStatic = true;
   });
-  pcre2 = super.pcre2.overrideAttrs (x: {
-    configureFlags = x.configureFlags ++ [ "--enable-static" ];
-  });
-  glib = super.glib.overrideAttrs (x: {
-    outputs = [ "bin" "out" "dev" ];
-    mesonFlags = [
-      "-Ddefault_library=static"
-      "-Ddevbindir=${placeholder ''dev''}/bin"
-      "-Dgtk_doc=false"
-      "-Dnls=disabled"
-    ];
-    postInstall = ''
-      moveToOutput "share/glib-2.0" "$dev"
-      substituteInPlace "$dev/bin/gdbus-codegen" --replace "$out" "$dev"
-      sed -i "$dev/bin/glib-gettextize" -e "s|^gettext_dir=.*|gettext_dir=$dev/share/glib-2.0/gettext|"
-      sed '1i#line 1 "${x.pname}-${x.version}/include/glib-2.0/gobject/gobjectnotifyqueue.c"' \
-        -i "$dev"/include/glib-2.0/gobject/gobjectnotifyqueue.c
-    '';
-  });
 }