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Test out the preview version of the next GKL (DO NOT MERGE) #8712

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@droazen droazen commented Mar 4, 2024

Test out the preview version of the GKL, containing the new native PDHMM.

The jar was build using Java 1.8 and contains AVX optimized binaries for Linux hosts and not optimized binaries for Mac (Intel CPUs)

Example code showing how to call into the PDHMM is here:
https://github.com/Intel-HLS/GKL/blob/master/src/test/java/com/intel/gkl/pdhmm/IntelPDHMMUnitTest.java

The jar was build using Java 1.8 and contains AVX optimized binaries for Linux hosts and
not optimized binaries for Mac (Intel CPUs)
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droazen commented Mar 4, 2024

@jamesemery Here's the branch we discussed -- see my notes above.

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jamesemery commented Apr 3, 2024

A command line that triggered the crash in our testing:

gatk HaplotypeCaller -R /cromwell_root/gcp-public-data--broad-references/hg38/v0/dragen_reference/Homo_sapiens_assembly38_masked.fasta -I gs://broad-dsde-methods-dragen/reprocessed_data_v3.7.5_masked/CH1_CHM13_WGS1/CH1_CHM13_WGS1.bam -L /cromwell_root/fc-971fd540-210c-4e5a-87ce-d3f8c91c7557/submissions/0586864c-d263-4797-89f1-b517e487ad2a/VariantCalling/b177671c-e96b-433e-824a-f9d641184e75/call-ScatterIntervalList/glob-cb4648beeaff920acb03de7603c06f98/109scattered.interval_list -O CH1_CHM13_WGS1.vcf.gz --pileup-detection --pileup-detection-absolute-alt-depth 0 --pileup-detection-bad-read-tolerance 0.4 --pileup-detection-enable-indel-pileup-calling --pileup-detection-active-region-phred-threshold 3.0 --use-pdhmm -contamination 0.0 -G StandardAnnotation -G StandardHCAnnotation --dragen-mode --disable-spanning-event-genotyping --dragstr-params-path /cromwell_root/fc-971fd540-210c-4e5a-87ce-d3f8c91c7557/submissions/0586864c-d263-4797-89f1-b517e487ad2a/VariantCalling/b177671c-e96b-433e-824a-f9d641184e75/call-DragstrAutoCalibration/CH1_CHM13_WGS1.bam.dragstr -GQB 10 -GQB 20 -GQB 30 -GQB 40 -GQB 50 -GQB 60 -GQB 70 -GQB 80 -GQB 90

--dragstr-params-path /cromwell_root/fc-971fd540-210c-4e5a-87ce-d3f8c91c7557/submissions/0586864c-d263-4797-89f1-b517e487ad2a/VariantCalling/b177671c-e96b-433e-824a-f9d641184e75/call-DragstrAutoCalibration/CH1_CHM13_WGS1.bam.dragstr is likely optional

-L is optional and any interval will likely work to reproduce the error.

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Github actions tests reported job failures from actions build 10011498561
Failures in the following jobs:

Test Type JDK Job ID Logs
variantcalling 17.0.6+10 10011498561.2 logs

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Github actions tests reported job failures from actions build 10012664149
Failures in the following jobs:

Test Type JDK Job ID Logs
variantcalling 17.0.6+10 10012664149.2 logs

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Github actions tests reported job failures from actions build 10063197705
Failures in the following jobs:

Test Type JDK Job ID Logs
variantcalling 17.0.6+10 10063197705.2 logs

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Github actions tests reported job failures from actions build 10063916773
Failures in the following jobs:

Test Type JDK Job ID Logs
variantcalling 17.0.6+10 10063916773.2 logs

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Github actions tests reported job failures from actions build 10063991760
Failures in the following jobs:

Test Type JDK Job ID Logs
variantcalling 17.0.6+10 10063991760.2 logs

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gatk-bot commented Jul 24, 2024

Github actions tests reported job failures from actions build 10078507648
Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10078507648.10 logs
variantcalling 17.0.6+10 10078507648.2 logs

…void overflows or memory issues in oversaturated assembly regions
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gatk-bot commented Jul 25, 2024

Github actions tests reported job failures from actions build 10099458986
Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10099458986.10 logs
variantcalling 17.0.6+10 10099458986.2 logs

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gatk-bot commented Jul 25, 2024

Github actions tests reported job failures from actions build 10099827390
Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10099827390.10 logs
variantcalling 17.0.6+10 10099827390.2 logs

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gatk-bot commented Jul 25, 2024

Github actions tests reported job failures from actions build 10099861078
Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10099861078.10 logs
variantcalling 17.0.6+10 10099861078.2 logs

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gatk-bot commented Jul 26, 2024

Github actions tests reported job failures from actions build 10114843161
Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10114843161.10 logs
variantcalling 17.0.6+10 10114843161.2 logs

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gatk-bot commented Jul 29, 2024

Github actions tests reported job failures from actions build 10146103273
Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10146103273.10 logs
variantcalling 17.0.6+10 10146103273.2 logs

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gatk-bot commented Aug 8, 2024

Github actions tests reported job failures from actions build 10306895203
Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10306895203.10 logs
unit 17.0.6+10 10306895203.12 logs
integration 17.0.6+10 10306895203.11 logs
unit 17.0.6+10 10306895203.1 logs
variantcalling 17.0.6+10 10306895203.2 logs
integration 17.0.6+10 10306895203.0 logs

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gatk-bot commented Sep 23, 2024

Github actions tests reported job failures from actions build 11000034591
Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 11000034591.10 logs
variantcalling 17.0.6+10 11000034591.2 logs

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