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Evaluate and potentially switch to use ClinVar's new VCV xml dump file #127

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newgene opened this issue Jul 21, 2021 · 1 comment
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data source new data source can be added. hub

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@newgene
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newgene commented Jul 21, 2021

VCV (variation in ClinVar) is a new variant-centric XML schema. More at https://pubmed.ncbi.nlm.nih.gov/31777943

MyVariant.info current imports data from ClinVar's original ClinVarFullRelease_*.xml.gz XML files (based on old RCV schema - no VCV content) at https://ftp.ncbi.nlm.nih.gov/pub/clinvar/xml/

The newer ClinVarVariationRelease_*.xml.gz XML files (based on VCV schema - includes all data in ClinVar) are at https://ftp.ncbi.nlm.nih.gov/pub/clinvar/xml/clinvar_variation/

Some variant-level aggregated interpretation, review status and explanation may only be available in VCV file.

@newgene newgene added data source new data source can be added. hub labels Jul 21, 2021
@obigriffith
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+1. CIViC would be very keen to display ClinVar aggregated classifications from myvariant.info!

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