diff --git a/patch/Python/Setup.iOS b/patch/Python/Setup.iOS
index 19af67d..c88af82 100644
--- a/patch/Python/Setup.iOS
+++ b/patch/Python/Setup.iOS
@@ -11,8 +11,7 @@ _ctypes _ctypes/_ctypes.c \
     -I$(srcdir)/Modules/_ctypes/darwin \
     -I$(srcdir)/../Support/libFFI/Headers \
     -DPy_BUILD_CORE_MODULE \
-    -DHAVE_FFI_PREP_CIF_VAR=1 \
-    -DHAVE_FFI_PREP_CLOSURE_LOC=1 -DHAVE_FFI_CLOSURE_ALLOC=1 \
+    -DHAVE_FFI_PREP_CLOSURE_LOC=1 \
     -L$(srcdir)/../Support/libFFI \
     -lFFI
 
diff --git a/patch/Python/Setup.tvOS b/patch/Python/Setup.tvOS
index c1a441c..e915b05 100644
--- a/patch/Python/Setup.tvOS
+++ b/patch/Python/Setup.tvOS
@@ -11,8 +11,7 @@ _ctypes _ctypes/_ctypes.c \
     -I$(srcdir)/Modules/_ctypes/darwin \
     -I$(srcdir)/../Support/libFFI/Headers \
     -DPy_BUILD_CORE_MODULE \
-    -DHAVE_FFI_PREP_CIF_VAR=1 \
-    -DHAVE_FFI_PREP_CLOSURE_LOC=1 -DHAVE_FFI_CLOSURE_ALLOC=1 \
+    -DHAVE_FFI_PREP_CLOSURE_LOC=1 \
     -L$(srcdir)/../Support/libFFI \
     -lFFI
 
diff --git a/patch/Python/Setup.watchOS b/patch/Python/Setup.watchOS
index 2bc6af9..1c44661 100644
--- a/patch/Python/Setup.watchOS
+++ b/patch/Python/Setup.watchOS
@@ -11,8 +11,7 @@ _ctypes _ctypes/_ctypes.c \
     -I$(srcdir)/Modules/_ctypes/darwin \
     -I$(srcdir)/../Support/libFFI/Headers \
     -DPy_BUILD_CORE_MODULE \
-    -DHAVE_FFI_PREP_CIF_VAR=1 \
-    -DHAVE_FFI_PREP_CLOSURE_LOC=1 -DHAVE_FFI_CLOSURE_ALLOC=1 \
+    -DHAVE_FFI_PREP_CLOSURE_LOC=1 \
     -L$(srcdir)/../Support/libFFI \
     -lFFI