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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="UTF-8">
<meta http-equiv="X-UA-Compatible" content="IE=edge">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<title>Shawn Tan - Personal Portfolio</title>
<!--
- favicon
-->
<link rel="shortcut icon" href="./assets/images/logo.ico" type="image/x-icon">
<!--
- custom css link
-->
<link rel="stylesheet" href="./assets/css/style.css">
<!--
- google font link
-->
<link rel="preconnect" href="https://fonts.googleapis.com">
<link rel="preconnect" href="https://fonts.gstatic.com" crossorigin>
<link href="https://fonts.googleapis.com/css2?family=Poppins:wght@300;400;500;600&display=swap" rel="stylesheet">
</head>
<body>
<!--
- #MAIN
-->
<main>
<!--
- #SIDEBAR
-->
<aside class="sidebar" data-sidebar>
<div class="sidebar-info">
<figure class="avatar-box">
<img src="./assets/images/my-avatar.png" alt="Shawn Tan" width="80">
</figure>
<div class="info-content">
<h1 class="name" title="Shawn Tan">Shawn Tan</h1>
<p class="title">Neuroscientist</p>
</div>
<button class="info_more-btn" data-sidebar-btn>
<span>Show Contacts</span>
<ion-icon name="chevron-down"></ion-icon>
</button>
</div>
<div class="sidebar-info_more">
<div class="separator"></div>
<ul class="contacts-list">
<li class="contact-item">
<div class="icon-box">
<ion-icon name="mail-outline"></ion-icon>
</div>
<div class="contact-info">
<p class="contact-title">Email</p>
<a href="mailto:[email protected]" class="contact-link">[email protected]</a>
</div>
</li>
<li class="contact-item">
<div class="icon-box">
<ion-icon name="logo-linkedin"></ion-icon>
</div>
<div class="contact-info">
<p class="contact-title">Linkedin</p>
<a href="https://www.linkedin.com/in/shawn-tan-873237b1/" class="contact-link">https://www.linkedin.com/in/shawn-tan-873237b1/</a>
</div>
</li>
<li class="contact-item">
<div class="icon-box">
<ion-icon name="logo-github"></ion-icon>
</div>
<div class="contact-info">
<p class="contact-title">Github</p>
<a href="https://github.com/banchan86" class="contact-link">https://github.com/banchan86</a>
</div>
</li>
<li class="contact-item">
<div class="icon-box">
<ion-icon name="location-outline"></ion-icon>
</div>
<div class="contact-info">
<p class="contact-title">Location</p>
<address>San Diego, California, USA</address>
</div>
</li>
</ul>
<div class="separator"></div>
</div>
</aside>
<!--
- #main-content
-->
<div class="main-content">
<!--
- #NAVBAR
-->
<nav class="navbar">
<ul class="navbar-list">
<li class="navbar-item">
<button class="navbar-link active" data-nav-link>About</button>
</li>
<li class="navbar-item">
<button class="navbar-link" data-nav-link>Resume</button>
</li>
<li class="navbar-item">
<button class="navbar-link" data-nav-link>Publications</button>
</li>
<li class="navbar-item">
<button class="navbar-link" data-nav-link>Skills</button>
</li>
<li class="navbar-item">
<button class="navbar-link" data-nav-link>Portfolio</button>
</li>
</ul>
</nav>
<!--
- #ABOUT
-->
<article class="about active" data-page="about">
<header>
<h2 class="h2 article-title">About me</h2>
</header>
<section class="about-text">
<p>
I am an experienced neuroscientist with a strong publication record and a background in molecular, cellular and systems neuroscience.
I am versatile in a wide variety of traditional and cutting edge neuroscience techniques, including molecular biology, microscopy, animal behaviour, electrophysiology and optogenetics (10+years wet lab experience).
</p>
<p>
In my spare time, I tinker with data and am proficient in statistics, coding, data science and machine learning (4+years experience with Python/Pandas/Scikit-learn/etc).
Check out the other tabs to take a look at some of my past projects!
</p>
</section>
<!--
- service
-->
<section class="service">
<h3 class="h3 service-title">Open to opportunities</h3>
<ul class="service-list">
<li class="service-item">
<div class="service-icon-box">
<ion-icon name="pulse-outline" size = large></ion-icon>
</div>
<div class="service-content-box">
<h4 class="h4 service-item-title">Field Application Scientist</h4>
<p class="service-item-text">
Imaging, electrophysiology, DNA sequencing.
</p>
</div>
</li>
<li class="service-item">
<div class="service-icon-box">
<ion-icon name="flask-outline" size = "large"></ion-icon>
</div>
<div class="service-content-box">
<h4 class="h4 service-item-title">Scientist</h4>
<p class="service-item-text">
Industry science, in-vivo applications, mice models.
</p>
</div>
</li>
<li class="service-item">
<div class="service-icon-box">
<ion-icon name="analytics-outline" size = "large"></ion-icon>
</div>
<div class="service-content-box">
<h4 class="h4 service-item-title">Consultancy</h4>
<p class="service-item-text">
Bespoke behavioral platforms, data analysis.
</p>
</div>
</li>
<li class="service-item">
<div class="service-icon-box">
<ion-icon name="document-text-outline" size = "large"></ion-icon>
</div>
<div class="service-content-box">
<h4 class="h4 service-item-title">Technical Writing</h4>
<p class="service-item-text">
Life science applications, open source platforms.
</p>
</div>
</li>
</ul>
</section>
<div class="modal-container" data-modal-container>
<div class="overlay" data-overlay></div>
<section class="testimonials-modal">
<button class="modal-close-btn" data-modal-close-btn>
<ion-icon name="close-outline"></ion-icon>
</button>
<div class="modal-img-wrapper">
<figure class="modal-avatar-box">
<img src="./assets/images/avatar-1.png" alt="Daniel lewis" width="80" data-modal-img>
</figure>
<img src="./assets/images/icon-quote.svg" alt="quote icon">
</div>
<div class="modal-content">
<h4 class="h3 modal-title" data-modal-title>Daniel lewis</h4>
<time datetime="2021-06-14">14 June, 2021</time>
<div data-modal-text>
<p>
Richard was hired to create a corporate identity. We were very pleased with the work done. She has a
lot of experience
and is very concerned about the needs of client. Lorem ipsum dolor sit amet, ullamcous cididt
consectetur adipiscing
elit, seds do et eiusmod tempor incididunt ut laborels dolore magnarels alia.
</p>
</div>
</div>
</section>
</div>
</article>
<!--
- #RESUME
-->
<article class="resume" data-page="resume">
<header>
<h2 class="h2 article-title">Resume</h2>
</header>
<section class="timeline">
<div class="title-wrapper">
<div class="icon-box">
<ion-icon name="briefcase-outline"></ion-icon>
</div>
<h3 class="h3">Experience</h3>
</div>
<ol class="timeline-list">
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Freelance Technical Writer</h4>
<span>Client - NeuroGEARS Ltd Mar 2024 - Present</span>
<p class="timeline-text">
• Write documentation, protocols, and tutorials to enhance user accessibility and engagement for Bonsai, an open-source software for constructing interactive systems for neuroscience experiments.
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Postdoctoral Associate</h4>
<span>The Scripps Research Institute 2019-2023</span>
<p class="timeline-text">
• Conducted research into the neural circuits underlying olfaction-driven social behavior in mice.
</p>
<br>
<p class="timeline-text">
• Developed and implemented signal processing and data analysis methods for physiological signals (respiration, pupil dilation) to study state-dependent modulation of arousal.
</p>
<br>
<p class="timeline-text">
• Setup and optimized machine learning pipelines for pose estimation and behavioral motif extraction to study postural and facial responses to olfactory stimuli.
</p>
<br>
<p class="timeline-text">
• Performed stereotaxic surgery, craniotomy, virus injections, fiber photometry, and optogenetics to monitor and manipulate neural activity, investigating the neural mechanisms underlying sexual arousal.
</p>
<br>
<p class="timeline-text">
• Designed and consulted on custom hardware/software setups for behavior, contributing to collaborative projects and high impact publications.
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">PhD Student and Postdoctoral Fellow</h4>
<span>DUKE-NUS Medical School 2011-2019</span>
<p class="timeline-text">
• Conducted research into the mechanisms underlying neuropsychiatric disorders using environmental, cellular and transgenic mice models.
</p>
<br>
<p class="timeline-text">
• Performed PCR, molecular cloning, HEK293 and neuronal cell culture, transient transfection, shRNA, lentivirus and AAV production to study disease mechanisms using transgene knockdown and over-expression.
</p>
<br>
<p class="timeline-text">
• Utilized western blot, qPCR, confocal microscopy, immunohistochemstry, in-situ hybridization and electrophysiology to quantify disease phenotypes.
</p>
<br>
<p class="timeline-text">
• Characterized behavioral abnormalities in mice models using a wide panel of behavioral assays targeting sensory and motor function, cognition, memory, social behaviors and neuropsychiatric phenotypes (anxiety/depression/schizophrenia/repetitive behaviors).
</p>
<br>
<p class="timeline-text">
• Published 2 first author and 3 collaborative publications in high impact journals and presented at international neuroscience conferences.
</p>
</li>
</ol>
</section>
<section class="timeline">
<div class="title-wrapper">
<div class="icon-box">
<ion-icon name="book-outline"></ion-icon>
</div>
<h3 class="h3">Education</h3>
</div>
<ol class="timeline-list">
<li class="timeline-item">
<h4 class="h4 timeline-item-title">PhD in Neuroscience</h4>
<span> NUS Graduate School for Integrative Sciences and Engineering (NGSS) 2011 — 2017</span>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">BSSc (Honors) in Psychology</h4>
<span>National University of Singapore (NUS) 2007-2011</span>
</li>
</ol>
</section>
<section class="timeline">
<div class="title-wrapper">
<div class="icon-box">
<ion-icon name="trophy-outline"></ion-icon>
</div>
<h3 class="h3">Awards</h3>
</div>
<ol class="timeline-list">
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Dorris Neuroscience Award</h4>
<span> The Scripps Research Institute 2021/2023</span>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Khoo Postdoctoral Fellowship Award</h4>
<span>Duke-NUS Medical School 2017</span>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">NUS Graduate School For Integrative Sciences and Engineering Scholarship</h4>
<span>National University of Singapore 2011</span>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Dean's List</h4>
<span>National University of Singapore 2008/2009</span>
</li>
</ol>
</section>
<section class="timeline">
<div class="title-wrapper">
<div class="icon-box">
<ion-icon name="people-circle-outline"></ion-icon>
</div>
<h3 class="h3">Teaching/Science Outreach</h3>
</div>
<ol class="timeline-list">
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Organizer and Chairman for NGSS student symposium.</h4>
<span>NUS Graduate School for Integrative Sciences and Engineering 2012-2013</span>
<p class="timeline-text">
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title"> Teaching assistant for Singapore Technological Endowment Program(STEP)/NUS Sunburst Brain Camp</h4>
<span>National University of Singapore (NUS) 2012-2013</span>
<p class="timeline-text">
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Teaching assistant for PL3253: Psychobiological Perspective of Emotions </h4>
<span>National University of Singapore (NUS) 2012</span>
<p class="timeline-text">
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Postgraduate mentor for Brain Book (a collaborative effort on a neuroscience book for adolescents)</h4>
<span>National University of Singapore (NUS) 2012</span>
<p class="timeline-text">
</p>
</li>
</ol>
</section>
</article>
<!--
- #Publications
-->
<article class="publications" data-page="publications">
<header>
<h2 class="h2 article-title">Publications</h2>
</header>
<section class="timeline">
<div class="title-wrapper">
<div class="icon-box">
<ion-icon name="book-outline"></ion-icon>
</div>
<h3 class="h3">Publications</h3>
</div>
<ol class="timeline-list">
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Vagal sensory neurons mediate the Bezold–Jarisch reflex and induce syncope</h4>
<span>Nature 623, 387–396 (2023)</span>
<p class="timeline-text">
Jonathan W Lovelace, Jingrui Ma, Saurabh Yadav, Karishma Chhabria, Hanbing Shen, Zhengyuan Pang, Tianbo Qi, Ruchi Sehgal,
Yunxiao Zhang, Tushar Bali, Thomas Vaissiere, <u>Shawn Tan</u>, Yuejia Liu, Gavin Rumbaugh, Li Ye, David Kleinfeld, Carsen Stringer,
Vineet Augustine <a href = "https://doi.org/10.1038/s41586-023-06680-7"><u>Link</u></a>
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Bespoke behavior: mechanisms that modulate pheromone-triggered behavior</h4>
<span>Current Opinion in Neurobiology 64, 143-150 (2020)</span>
<p class="timeline-text">
<u>Shawn Tan</u>, Lisa Stowers
<a href = "https://doi.org/10.1016/j.conb.2020.05.003"><u>Link</u></a>
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Prenatal selective serotonin reuptake inhibitor (SSRI) exposure induces working memory and social recognition deficits by disrupting inhibitory synaptic networks in male mice</h4>
<span>Molecular Brain 12(1), 29 (2019)</span>
<p class="timeline-text">
Weonjin Yu, Yi-Chun Yen, Young-Hwan Lee, <u>Shawn Tan</u>, Yixin Xiao, Hidayat Lokman, Audrey Khoo Tze Ting, Hasini Ganegala, Taejoon Kwon, Won-Kyung Ho, Hyunsoo Shawn Je
<a href = "https://doi.org/10.1186/s13041-019-0452-5"><u>Link</u></a>
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Postnatal TrkB ablation in corticolimbic interneurons induces social dominance in male mice</h4>
<span>Proceedings of the National Academy of Sciences 115(42), E9909-E9915 (2018)</span>
<p class="timeline-text">
<u>Shawn Tan</u>, Yixin Xiao, Henry H Yin, Albert I Chen, Tuck Wah Soong, Hyunsoo Shawn Je
<a href = "https://doi.org/10.1073/pnas.1812083115"><u>Link</u></a>
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Maternal separation does not produce a significant behavioral change in mice</h4>
<span>Experimental Neurobiology 26(6), 390-398 (2017) </span>
<p class="timeline-text">
<u>Shawn Tan</u>, Hin San Ho, Anna Yoonsu Song, Joey Low, Hyunsoo Shawn Je
<a href = "https://doi.org/10.5607/en.2017.26.6.390"><u>Link</u></a>
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Direct induction and functional maturation of forebrain GABAergic neurons from human pluripotent stem cells</h4>
<span>Cell reports 16(7), 1942-1953 (2016)</span>
<p class="timeline-text">
Alfred Xuyang Sun, Qiang Yuan, <u>Shawn Tan</u>, Yixin Xiao, Danlei Wang, Audrey Tze Ting Khoo, Levena Sani, Hoang-Dai Tran, Paul Kim, Yong Seng Chiew, Kea Joo Lee, Yi-Chun Yen, Huck Hui Ng, Bing Lim, Hyunsoo Shawn Je
<a href = "https://doi.org/10.1016/j.celrep.2016.07.035"><u>Link</u></a>
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Regulation of brain-derived neurotrophic factor exocytosis and gamma-aminobutyric acidergic interneuron synapse by the schizophrenia susceptibility gene dysbindin-1</h4>
<span>Biological Psychiatry 80(4), 312-322 (2016) </span>
<p class="timeline-text">
Qiang Yuan, Feng Yang, Yixin Xiao, <u>Shawn Tan</u>, Nilofer Husain, Ming Ren, Zhonghua Hu, Keri Martinowich, Julia S Ng, Paul J Kim, Weiping Han, Koh-ichi Nagata, Daniel R Weinberger, Hyunsoo Shawn Je
<a href = "https://doi.org/10.1016/j.biopsych.2015.08.019"><u>Link</u></a>
</p>
</li>
</ol>
</section>
</article>
<!--
- #Skills
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<article class="skills" data-page="skills">
<header>
<h2 class="h2 article-title">Skills</h2>
</header>
<section class="service">
<h3 class="h3 service-title">Technical Skills</h3>
<ul class="service-list">
<li class="service-item">
<div class="service-icon-box">
<ion-icon name="flask-outline" size="large"></ion-icon>
</div>
<div class="service-content-box">
<h4 class="h4 service-item-title">Molecular Neuroscience</h4>
<p class="service-item-text">
AAV/Lentivirus Production, Genotyping, Knockdown and Over-expression Assays,
Mammalian Cell Culture (HEK293T and Mouse Primary Neurons), Molecular Cloning,
Nucleic Acid Extraction, Patch Clamp Electrophysiology, PCR, qPCR, Western Blot.
</p>
</div>
</li>
<li class="service-item">
<div class="service-icon-box">
<ion-icon name="paw-outline" size="large"></ion-icon>
</div>
<div class="service-content-box">
<h4 class="h4 service-item-title">System Neuroscience</h4>
<p class="service-item-text">
Confocal Microscopy, Histology, Fiber Photometry, Fluorescence Immunohistochemstry, Functional Ultrasound Imaging,
In-situ Hybridization, In-vivo electrophysiology (single unit recording/LFP), Mice Behavioural Assays, Optogenetics, Stereotaxic Surgery.
</p>
</div>
</li>
<li class="service-item">
<div class="service-icon-box">
<ion-icon name="analytics-outline" size = "large"></ion-icon>
</div>
<div class="service-content-box">
<h4 class="h4 service-item-title">Data Science</h4>
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DeepLabCut, Graphpad Prism, Jupyter Notebook, Matplotlib, Moseq, Python, Pandas, Scikit-learn, Scipy, Seaborn, Numpy.
</p>
</div>
</li>
<li class="service-item">
<div class="service-icon-box">
<ion-icon name="print-outline" size = "large"></ion-icon>
</div>
<div class="service-content-box">
<h4 class="h4 service-item-title">Office Tools</h4>
<p class="service-item-text">
Adobe Illustrator and Photoshop, Github, Discord, Google Suite, Microsoft Office (Excel, Onenote, Outlook, Powerpoint, Word), Slack, Zoom.
</p>
</div>
</li>
</ul>
</section>
<section class="timeline">
<div class="title-wrapper">
<div class="icon-box">
<ion-icon name="document-outline"></ion-icon>
</div>
<h3 class="h3">Courses and Certifications</h3>
</div>
<ol class="timeline-list">
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Introduction to Git and Github</h4>
<p class="timeline-text">
~ 30 hour course covering version control, working with local and remote repositories, and best practices for online collaborations.
</p>
<span>Coursera (Google) (2024)</span>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Deep Learning in Neuroscience</h4>
<span>Neuromatch Academy (2021)</span>
<p class="timeline-text">
~ 120 hour intensive, interactive live course covering core topics in deep learning, including optimization, regularization, generative models, unsupervised and reinforcement learning using Pytorch.
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Applied Data Science with Python Specialization</h4>
<span>Coursera (University of Michigan) (2021)</span>
<p class="timeline-text">
~ 160 hour course covering data processing, data visualization, statistical analysis and machine learning using Pandas, Matplotlib, Scikit-learn, NLTK and NetworkX pythons libraries.
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Fundamentals of Computing Specialization</h4>
<span>Coursera (Rice University) (2018)</span>
<p class="timeline-text">
~ 80 hour course building on Python fundamentals and covering interactive programming, algorithimic thinking and object-oriented programming.
</p>
</li>
<li class="timeline-item">
<h4 class="h4 timeline-item-title">Python for Everybody Specialization</h4>
<span>Coursera (University of Michigan) (2018)</span>
<p class="timeline-text">
~ 80 hour course covering fundamental Python programming concepts such as functions, data structures, and accessing networked application programming interfaces.
</p>
</li>
</ol>
</section>
</article>
<!--
- #PORTFOLIO
-->
<article class="portfolio" data-page="portfolio">
<header>
<h2 class="h2 article-title">Portfolio</h2>
</header>
<section class="projects">
<ul class="filter-list">
<li class="filter-item">
<button class="active" data-filter-btn>All</button>
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<li class="filter-item">
<button data-filter-btn>Behaviour Setups</button>
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<button data-filter-btn>Data Analysis</button>
</li>
<li class="filter-item">
<button data-filter-btn>Under construction - more to be added!</button>
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<div class="select-value" data-selecct-value>Select category</div>
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</button>
<ul class="select-list">
<li class="select-item">
<button data-select-item>All</button>
</li>
<li class="select-item">
<button data-select-item>Behaviour Setups</button>
</li>
<li class="select-item">
<button data-select-item>Data Analysis</button>
</li>
<li class="select-item">
<button data-select-item>Under construction - more to be added!</button>
</li>
</ul>
</div>
<ul class="project-list">
<li class="project-item active" data-filter-item data-category="behaviour setups">
<a href="#">
<figure class="project-img">
<div class="project-item-icon-box">
<ion-icon name="eye-outline"></ion-icon>
</div>
<img src="./assets/videos/observatory_neutral.webp" alt="Observatory" loading="lazy">
</figure>
<h3 class="project-title">Observatory - multi-dimensional characterization of mice behavior</h3>
<p class="project-category">Behaviour Setups</p>
</a>
</li>
<li class="project-item active" data-filter-item data-category="data analysis">
<a href="#">
<figure class="project-img">
<div class="project-item-icon-box">
<ion-icon name="eye-outline"></ion-icon>
</div>
<img src="./assets/videos/deeplabcut_face.webp" alt="Classification of Facial Features to Odorants" loading="lazy">
</figure>
<h3 class="project-title">Classification of Facial Features to Odorants</h3>
<p class="project-category">Data Analysis</p>
</a>
</li>
<li class="project-item active" data-filter-item data-category="data analysis">
<a href="#">
<figure class="project-img">
<div class="project-item-icon-box">
<ion-icon name="eye-outline"></ion-icon>
</div>
<img src="./assets/videos/moseq_video.webp" alt="fundo" loading="lazy">
</figure>
<h3 class="project-title">Extraction of behavioral motifs with Moseq</h3>
<p class="project-category">Data Analysis</p>
</a>
</li>
</ul>
</section>
</article>
</div>
</main>
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