diff --git a/onnxruntime/core/providers/vitisai/imp/global_api.cc b/onnxruntime/core/providers/vitisai/imp/global_api.cc
index 8f4882bf9333a..772e778dd5ed4 100644
--- a/onnxruntime/core/providers/vitisai/imp/global_api.cc
+++ b/onnxruntime/core/providers/vitisai/imp/global_api.cc
@@ -54,6 +54,10 @@ struct OrtVitisAIEpAPI {
   int (*vitisai_ep_on_run_start)(
       const std::vector<std::unique_ptr<vaip_core::ExecutionProvider>>& eps, const void* state,
       vaip_core::DllSafe<std::string> (*get_config_entry)(const void* state, const char* entry_name)) = nullptr;
+  int (*vitisai_ep_set_ep_dynamic_options)(
+      const std::vector<std::unique_ptr<vaip_core::ExecutionProvider>>& eps,
+      const char* const* keys,
+      const char* const* values, size_t kv_len) = nullptr;
   void Ensure() {
     if (handle_)
       return;
@@ -79,6 +83,7 @@ struct OrtVitisAIEpAPI {
                                            (void**)&vaip_get_version);
     ORT_THROW_IF_ERROR(env.GetSymbolFromLibrary(handle_, "create_ep_context_nodes", (void**)&create_ep_context_nodes));
     ORT_THROW_IF_ERROR(env.GetSymbolFromLibrary(handle_, "vitisai_ep_on_run_start", (void**)&vitisai_ep_on_run_start));
+    ORT_THROW_IF_ERROR(env.GetSymbolFromLibrary(handle_, "vitisai_ep_set_ep_dynamic_options", (void**)&vitisai_ep_set_ep_dynamic_options));
   }
 
  private:
@@ -120,6 +125,15 @@ int vitisai_ep_on_run_start(
   return 100;
 }
 
+int vitisai_ep_set_ep_dynamic_options(
+    const std::vector<std::unique_ptr<vaip_core::ExecutionProvider>>& eps, const char* const* keys,
+    const char* const* values, size_t kv_len) {
+  if (s_library_vitisaiep.vitisai_ep_set_ep_dynamic_options) {
+    return s_library_vitisaiep.vitisai_ep_set_ep_dynamic_options(eps, keys, values, kv_len);
+  }
+  return 100;
+}
+
 struct MyCustomOpKernel : OpKernel {
   MyCustomOpKernel(const OpKernelInfo& info, const OrtCustomOp& op) : OpKernel(info), op_(op) {
     op_kernel_ =
diff --git a/onnxruntime/core/providers/vitisai/include/vaip/global_api.h b/onnxruntime/core/providers/vitisai/include/vaip/global_api.h
index 1a90f4c7fdebb..b0353bd6adae9 100644
--- a/onnxruntime/core/providers/vitisai/include/vaip/global_api.h
+++ b/onnxruntime/core/providers/vitisai/include/vaip/global_api.h
@@ -20,3 +20,7 @@ std::optional<std::vector<onnxruntime::Node*>> create_ep_context_nodes(
 int vitisai_ep_on_run_start(
     const std::vector<std::unique_ptr<vaip_core::ExecutionProvider>>& eps, const void* state,
     vaip_core::DllSafe<std::string> (*get_config_entry)(const void* state, const char* entry_name));
+int vitisai_ep_set_ep_dynamic_options(
+    const std::vector<std::unique_ptr<vaip_core::ExecutionProvider>>& eps,
+    const char* const* keys,
+    const char* const* values, size_t kv_len);
diff --git a/onnxruntime/core/providers/vitisai/vitisai_execution_provider.cc b/onnxruntime/core/providers/vitisai/vitisai_execution_provider.cc
index 09b115b4a57fc..633847e6f163b 100644
--- a/onnxruntime/core/providers/vitisai/vitisai_execution_provider.cc
+++ b/onnxruntime/core/providers/vitisai/vitisai_execution_provider.cc
@@ -110,9 +110,19 @@ common::Status VitisAIExecutionProvider::OnRunStart(const onnxruntime::RunOption
   };
   auto error_code = vitisai_ep_on_run_start(**execution_providers_, (const void*)&run_options, get_config_entry);
   if (error_code) {
-    return Status(onnxruntime::common::ONNXRUNTIME, onnxruntime::common::StatusCode::FAIL, std::to_string(error_code));
+    std::string error_msg = "vitisai_ep_on_run_start ret: " + std::to_string(error_code);
+    return Status(onnxruntime::common::ONNXRUNTIME, onnxruntime::common::StatusCode::FAIL, error_msg);
   }
   return Status::OK();
 }
 
+common::Status VitisAIExecutionProvider::SetEpDynamicOptions(gsl::span<const char* const> keys,
+                                                             gsl::span<const char* const> values) {
+  auto error_code = vitisai_ep_set_ep_dynamic_options(**execution_providers_, keys.data(), values.data(), std::min(keys.size(), values.size()));
+  if (error_code) {
+    std::string error_msg = "vitisai_ep_set_ep_dynamic_options ret: " + std::to_string(error_code);
+    return Status(onnxruntime::common::ONNXRUNTIME, onnxruntime::common::StatusCode::FAIL, error_msg);
+  }
+  return Status::OK();
+}
 }  // namespace onnxruntime
diff --git a/onnxruntime/core/providers/vitisai/vitisai_execution_provider.h b/onnxruntime/core/providers/vitisai/vitisai_execution_provider.h
index 05d2a976815b9..07085cd248d06 100644
--- a/onnxruntime/core/providers/vitisai/vitisai_execution_provider.h
+++ b/onnxruntime/core/providers/vitisai/vitisai_execution_provider.h
@@ -39,6 +39,8 @@ class VitisAIExecutionProvider : public IExecutionProvider {
   // This method is called after both `GetComputeCapabilityOps()` and `Compile()`.
   // This timing is required to work with both compliation-based EPs and non-compilation-based EPs.
   const InlinedVector<const Node*> GetEpContextNodes() const override;
+  virtual common::Status SetEpDynamicOptions(gsl::span<const char* const> /*keys*/,
+                                             gsl::span<const char* const> /*values*/) override;
 
  private:
   using my_ep_t = vaip_core::DllSafe<std::vector<std::unique_ptr<vaip_core::ExecutionProvider>>>;