diff --git a/methscan/cli.py b/methscan/cli.py index 3467f53..6fff4f0 100755 --- a/methscan/cli.py +++ b/methscan/cli.py @@ -387,9 +387,8 @@ def smooth_cli(**kwargs): show_default=True, type=click.FloatRange(min=0, max=1), metavar="FLOAT", - help="The variance threshold, i.e. 0.02 means that the top 2% " - "most variable genomic bins will be reported. Overlapping variable bins " - "are merged.", + help="The variance threshold, i.e. 0.02 means that the top 2% most variable " + "genomic bins will be merged and reported as VMRs.", ) @click.option( "--min-cells", @@ -489,9 +488,9 @@ def scan_cli(**kwargs): show_default=True, type=click.FloatRange(min=0, max=1), metavar="FLOAT", - help="The t-statistic threshold, i.e. 0.02 means that the top 2% " - "most differentially methylated genomic bins will be reported. " - "Overlapping bins are merged.", + help="The t-statistic threshold, i.e. 0.02 means that the top 2% and " + "bottom 2% most differentially methylated genomic bins will be separately " + "merged and reported as DMRs with adjusted p-values." ) @click.option( "--min-cells", @@ -508,8 +507,8 @@ def scan_cli(**kwargs): default=0, type=click.IntRange(min=0), metavar="INTEGER", - help="Merge neighboring VMRs if they are within this distance in basepairs. Useful " - "to prevent fragmented VMRs separated only by small gaps. [default: off]", + help="Merge neighboring DMRs if they are within this distance in basepairs. Useful " + "to prevent fragmented DMRs separated only by small gaps. [default: off]", ) @click.option( "--threads",