diff --git a/test/unit/data/datatypes/test_sequence.py b/test/unit/data/datatypes/test_sequence.py
index fefc6963121b..64982e89d637 100644
--- a/test/unit/data/datatypes/test_sequence.py
+++ b/test/unit/data/datatypes/test_sequence.py
@@ -1,12 +1,24 @@
+import pytest
+
 from galaxy.datatypes.sequence import (
     Fasta,
     FastqSanger,
     FastqSolexa,
 )
-from .util import get_dataset
+from .util import (
+    get_dataset,
+    MockDatasetDataset,
+)
 
 
-def test_fasta_set_meta():
+@pytest.mark.parametrize(
+    "input_file",
+    [
+        "1.fasta",
+        "1.fasta.gz",
+    ],
+)
+def test_fasta_set_meta(input_file):
     b = Fasta()
     with get_dataset("1.fasta") as dataset:
         b.set_meta(dataset=dataset)
@@ -14,41 +26,19 @@ def test_fasta_set_meta():
         assert dataset.metadata.sequences == 1
 
 
-def test_fastagz_set_meta():
-    b = Fasta()
-    with get_dataset("1.fasta.gz") as dataset:
-        b.set_meta(dataset=dataset)
-        assert dataset.metadata.data_lines == 2
-        assert dataset.metadata.sequences == 1
-
-
-def test_fastqsanger_set_meta():
-    b = FastqSanger()
+@pytest.mark.parametrize(
+    "fastq_type,input_file",
+    [
+        [FastqSanger, "1.fastqsanger"],
+        [FastqSanger, "1.fastqsanger.gz"],
+        [FastqSanger, "1.fastqsanger.bz2"],
+        [FastqSolexa, "1.fastqssolexa"],
+    ],
+)
+def test_fastqsanger_set_meta(fastq_type, input_file):
+    b = fastq_type()
     with get_dataset("1.fastqsanger") as dataset:
-        b.set_meta(dataset=dataset)
-        assert dataset.metadata.data_lines == 8
-        assert dataset.metadata.sequences == 2
-
-
-def test_fastqsangergz_set_meta():
-    b = FastqSanger()
-    with get_dataset("1.fastqsanger.gz") as dataset:
-        b.set_meta(dataset=dataset)
-        assert dataset.metadata.data_lines == 8
-        assert dataset.metadata.sequences == 2
-
-
-def test_fastqsangerbz2_set_meta():
-    b = FastqSanger()
-    with get_dataset("1.fastqsanger.bz2") as dataset:
-        b.set_meta(dataset=dataset)
-        assert dataset.metadata.data_lines == 8
-        assert dataset.metadata.sequences == 2
-
-
-def test_fastqsolexa_set_meta():
-    b = FastqSolexa()
-    with get_dataset("1.fastqsolexa") as dataset:
+        dataset.dataset = MockDatasetDataset(dataset.get_file_name())
         b.set_meta(dataset=dataset)
         assert dataset.metadata.data_lines == 8
         assert dataset.metadata.sequences == 2