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COG_Classifications.txt
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[H] COG0001 Glutamate-1-semialdehyde aminotransferase
[E] COG0002 Acetylglutamate semialdehyde dehydrogenase
[P] COG0003 Oxyanion-translocating ATPase
[P] COG0004 Ammonia permease
[F] COG0005 Purine nucleoside phosphorylase
[E] COG0006 Xaa-Pro aminopeptidase
[H] COG0007 Uroporphyrinogen-III methylase
[J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases
[J] COG0009 Putative translation factor (SUA5)
[E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family
[S] COG0011 Uncharacterized conserved protein
[J] COG0012 Predicted GTPase, probable translation factor
[J] COG0013 Alanyl-tRNA synthetase
[E] COG0014 Gamma-glutamyl phosphate reductase
[F] COG0015 Adenylosuccinate lyase
[J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit
[J] COG0017 Aspartyl/asparaginyl-tRNA synthetases
[J] COG0018 Arginyl-tRNA synthetase
[E] COG0019 Diaminopimelate decarboxylase
[I] COG0020 Undecaprenyl pyrophosphate synthase
[G] COG0021 Transketolase
[C] COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
[J] COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins
[J] COG0024 Methionine aminopeptidase
[P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters
[F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
[F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)
[EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
[H] COG0029 Aspartate oxidase
[J] COG0030 Dimethyladenosine transferase (rRNA methylation)
[E] COG0031 Cysteine synthase
[G] COG0033 Phosphoglucomutase
[F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase
[F] COG0035 Uracil phosphoribosyltransferase
[G] COG0036 Pentose-5-phosphate-3-epimerase
[D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
[P] COG0038 Chloride channel protein EriC
[C] COG0039 Malate/lactate dehydrogenases
[E] COG0040 ATP phosphoribosyltransferase
[F] COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
[J] COG0042 tRNA-dihydrouridine synthase
[H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
[F] COG0044 Dihydroorotase and related cyclic amidohydrolases
[C] COG0045 Succinyl-CoA synthetase, beta subunit
[F] COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
[F] COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain
[J] COG0048 Ribosomal protein S12
[J] COG0049 Ribosomal protein S7
[J] COG0050 GTPases - translation elongation factors
[J] COG0051 Ribosomal protein S10
[J] COG0052 Ribosomal protein S2
[P] COG0053 Predicted Co/Zn/Cd cation transporters
[H] COG0054 Riboflavin synthase beta-chain
[C] COG0055 F0F1-type ATP synthase, beta subunit
[C] COG0056 F0F1-type ATP synthase, alpha subunit
[G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
[G] COG0058 Glucan phosphorylase
[EH] COG0059 Ketol-acid reductoisomerase
[J] COG0060 Isoleucyl-tRNA synthetase
[G] COG0061 Predicted sugar kinase
[S] COG0062 Uncharacterized conserved protein
[G] COG0063 Predicted sugar kinase
[J] COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog)
[E] COG0065 3-isopropylmalate dehydratase large subunit
[E] COG0066 3-isopropylmalate dehydratase small subunit
[E] COG0067 Glutamate synthase domain 1
[O] COG0068 Hydrogenase maturation factor
[E] COG0069 Glutamate synthase domain 2
[E] COG0070 Glutamate synthase domain 3
[O] COG0071 Molecular chaperone (small heat shock protein)
[J] COG0072 Phenylalanyl-tRNA synthetase beta subunit
[R] COG0073 EMAP domain
[C] COG0074 Succinyl-CoA synthetase, alpha subunit
[E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase
[E] COG0076 Glutamate decarboxylase and related PLP-dependent proteins
[E] COG0077 Prephenate dehydratase
[E] COG0078 Ornithine carbamoyltransferase
[E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
[J] COG0080 Ribosomal protein L11
[J] COG0081 Ribosomal protein L1
[E] COG0082 Chorismate synthase
[E] COG0083 Homoserine kinase
[L] COG0084 Mg-dependent DNase
[K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit
[K] COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit
[J] COG0087 Ribosomal protein L3
[J] COG0088 Ribosomal protein L4
[J] COG0089 Ribosomal protein L23
[J] COG0090 Ribosomal protein L2
[J] COG0091 Ribosomal protein L22
[J] COG0092 Ribosomal protein S3
[J] COG0093 Ribosomal protein L14
[J] COG0094 Ribosomal protein L5
[H] COG0095 Lipoate-protein ligase A
[J] COG0096 Ribosomal protein S8
[J] COG0097 Ribosomal protein L6P/L9E
[J] COG0098 Ribosomal protein S5
[J] COG0099 Ribosomal protein S13
[J] COG0100 Ribosomal protein S11
[J] COG0101 Pseudouridylate synthase
[J] COG0102 Ribosomal protein L13
[J] COG0103 Ribosomal protein S9
[F] COG0104 Adenylosuccinate synthase
[F] COG0105 Nucleoside diphosphate kinase
[E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
[E] COG0107 Imidazoleglycerol-phosphate synthase
[H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase
[O] COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor)
[R] COG0110 Acetyltransferase (isoleucine patch superfamily)
[HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases
[E] COG0112 Glycine/serine hydroxymethyltransferase
[H] COG0113 Delta-aminolevulinic acid dehydratase
[C] COG0114 Fumarase
[EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
[L] COG0116 Predicted N6-adenine-specific DNA methylase
[H] COG0117 Pyrimidine deaminase
[E] COG0118 Glutamine amidotransferase
[E] COG0119 Isopropylmalate/homocitrate/citramalate synthases
[G] COG0120 Ribose 5-phosphate isomerase
[R] COG0121 Predicted glutamine amidotransferase
[L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein
[J] COG0124 Histidyl-tRNA synthetase
[F] COG0125 Thymidylate kinase
[G] COG0126 3-phosphoglycerate kinase
[F] COG0127 Xanthosine triphosphate pyrophosphatase
[E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase
[EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase
[J] COG0130 Pseudouridine synthase
[E] COG0131 Imidazoleglycerol-phosphate dehydratase
[H] COG0132 Dethiobiotin synthetase
[E] COG0133 Tryptophan synthase beta chain
[E] COG0134 Indole-3-glycerol phosphate synthase
[E] COG0135 Phosphoribosylanthranilate isomerase
[E] COG0136 Aspartate-semialdehyde dehydrogenase
[E] COG0137 Argininosuccinate synthase
[F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
[E] COG0139 Phosphoribosyl-AMP cyclohydrolase
[E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase
[E] COG0141 Histidinol dehydrogenase
[H] COG0142 Geranylgeranyl pyrophosphate synthase
[J] COG0143 Methionyl-tRNA synthetase
[J] COG0144 tRNA and rRNA cytosine-C5-methylases
[EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit
[EQ] COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit
[EH] COG0147 Anthranilate/para-aminobenzoate synthases component I
[G] COG0148 Enolase
[G] COG0149 Triosephosphate isomerase
[F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase
[F] COG0151 Phosphoribosylamine-glycine ligase
[F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase
[G] COG0153 Galactokinase
[J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases
[P] COG0155 Sulfite reductase, beta subunit (hemoprotein)
[H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
[H] COG0157 Nicotinate-nucleotide pyrophosphorylase
[G] COG0158 Fructose-1,6-bisphosphatase
[E] COG0159 Tryptophan synthase alpha chain
[E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases
[H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
[J] COG0162 Tyrosyl-tRNA synthetase
[H] COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase
[L] COG0164 Ribonuclease HII
[E] COG0165 Argininosuccinate lyase
[G] COG0166 Glucose-6-phosphate isomerase
[F] COG0167 Dihydroorotate dehydrogenase
[P] COG0168 Trk-type K+ transport systems, membrane components
[E] COG0169 Shikimate 5-dehydrogenase
[I] COG0170 Dolichol kinase
[H] COG0171 NAD synthase
[J] COG0172 Seryl-tRNA synthetase
[J] COG0173 Aspartyl-tRNA synthetase
[E] COG0174 Glutamine synthetase
[EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
[G] COG0176 Transaldolase
[L] COG0177 Predicted EndoIII-related endonuclease
[L] COG0178 Excinuclease ATPase subunit
[Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
[J] COG0180 Tryptophanyl-tRNA synthetase
[H] COG0181 Porphobilinogen deaminase
[J] COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family
[I] COG0183 Acetyl-CoA acetyltransferase
[J] COG0184 Ribosomal protein S15P/S13E
[J] COG0185 Ribosomal protein S19
[J] COG0186 Ribosomal protein S17
[L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
[L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
[HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
[H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
[G] COG0191 Fructose/tagatose bisphosphate aldolase
[H] COG0192 S-adenosylmethionine synthetase
[J] COG0193 Peptidyl-tRNA hydrolase
[F] COG0194 Guanylate kinase
[K] COG0195 Transcription elongation factor
[H] COG0196 FAD synthase
[J] COG0197 Ribosomal protein L16/L10E
[J] COG0198 Ribosomal protein L24
[J] COG0199 Ribosomal protein S14
[J] COG0200 Ribosomal protein L15
[U] COG0201 Preprotein translocase subunit SecY
[K] COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit
[J] COG0203 Ribosomal protein L17
[I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase
[G] COG0205 6-phosphofructokinase
[D] COG0206 Cell division GTPase
[F] COG0207 Thymidylate synthase
[F] COG0208 Ribonucleotide reductase, beta subunit
[F] COG0209 Ribonucleotide reductase, alpha subunit
[L] COG0210 Superfamily I DNA and RNA helicases
[J] COG0211 Ribosomal protein L27
[H] COG0212 5-formyltetrahydrofolate cyclo-ligase
[F] COG0213 Thymidine phosphorylase
[H] COG0214 Pyridoxine biosynthesis enzyme
[J] COG0215 Cysteinyl-tRNA synthetase
[J] COG0216 Protein chain release factor A
[S] COG0217 Uncharacterized conserved protein
[R] COG0218 Predicted GTPase
[J] COG0219 Predicted rRNA methylase (SpoU class)
[R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase
[C] COG0221 Inorganic pyrophosphatase
[J] COG0222 Ribosomal protein L7/L12
[J] COG0223 Methionyl-tRNA formyltransferase
[C] COG0224 F0F1-type ATP synthase, gamma subunit
[O] COG0225 Peptide methionine sulfoxide reductase
[P] COG0226 ABC-type phosphate transport system, periplasmic component
[J] COG0227 Ribosomal protein L28
[J] COG0228 Ribosomal protein S16
[O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase
[J] COG0230 Ribosomal protein L34
[J] COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)
[F] COG0232 dGTP triphosphohydrolase
[J] COG0233 Ribosome recycling factor
[O] COG0234 Co-chaperonin GroES (HSP10)
[G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
[IQ] COG0236 Acyl carrier protein
[H] COG0237 Dephospho-CoA kinase
[J] COG0238 Ribosomal protein S18
[D] COG0239 Integral membrane protein possibly involved in chromosome condensation
[C] COG0240 Glycerol-3-phosphate dehydrogenase
[E] COG0241 Histidinol phosphatase and related phosphatases
[J] COG0242 N-formylmethionyl-tRNA deformylase
[C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing
[J] COG0244 Ribosomal protein L10
[I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
[G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases
[C] COG0247 Fe-S oxidoreductase
[FP] COG0248 Exopolyphosphatase
[L] COG0249 Mismatch repair ATPase (MutS family)
[K] COG0250 Transcription antiterminator
[J] COG0251 Putative translation initiation inhibitor, yjgF family
[EJ] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
[E] COG0253 Diaminopimelate epimerase
[J] COG0254 Ribosomal protein L31
[J] COG0255 Ribosomal protein L29
[J] COG0256 Ribosomal protein L18
[J] COG0257 Ribosomal protein L36
[L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI)
[H] COG0259 Pyridoxamine-phosphate oxidase
[E] COG0260 Leucyl aminopeptidase
[J] COG0261 Ribosomal protein L21
[H] COG0262 Dihydrofolate reductase
[E] COG0263 Glutamate 5-kinase
[J] COG0264 Translation elongation factor Ts
[O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
[L] COG0266 Formamidopyrimidine-DNA glycosylase
[J] COG0267 Ribosomal protein L33
[J] COG0268 Ribosomal protein S20
[G] COG0269 3-hexulose-6-phosphate synthase and related proteins
[L] COG0270 Site-specific DNA methylase
[T] COG0271 Stress-induced morphogen (activity unknown)
[L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II)
[F] COG0274 Deoxyribose-phosphate aldolase
[M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
[H] COG0276 Protoheme ferro-lyase (ferrochelatase)
[C] COG0277 FAD/FMN-containing dehydrogenases
[O] COG0278 Glutaredoxin-related protein
[G] COG0279 Phosphoheptose isomerase
[C] COG0280 Phosphotransacetylase
[C] COG0281 Malic enzyme
[C] COG0282 Acetate kinase
[F] COG0283 Cytidylate kinase
[F] COG0284 Orotidine-5'-phosphate decarboxylase
[H] COG0285 Folylpolyglutamate synthase
[V] COG0286 Type I restriction-modification system methyltransferase subunit
[E] COG0287 Prephenate dehydrogenase
[P] COG0288 Carbonic anhydrase
[E] COG0289 Dihydrodipicolinate reductase
[J] COG0290 Translation initiation factor 3 (IF-3)
[J] COG0291 Ribosomal protein L35
[J] COG0292 Ribosomal protein L20
[J] COG0293 23S rRNA methylase
[H] COG0294 Dihydropteroate synthase and related enzymes
[F] COG0295 Cytidine deaminase
[G] COG0296 1,4-alpha-glucan branching enzyme
[G] COG0297 Glycogen synthase
[O] COG0298 Hydrogenase maturation factor
[F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN
[R] COG0300 Short-chain dehydrogenases of various substrate specificities
[H] COG0301 Thiamine biosynthesis ATP pyrophosphatase
[H] COG0302 GTP cyclohydrolase I
[H] COG0303 Molybdopterin biosynthesis enzyme
[IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase
[L] COG0305 Replicative DNA helicase
[P] COG0306 Phosphate/sulphate permeases
[H] COG0307 Riboflavin synthase alpha chain
[E] COG0308 Aminopeptidase N
[O] COG0309 Hydrogenase maturation factor
[P] COG0310 ABC-type Co2+ transport system, permease component
[H] COG0311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis
[R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs
[R] COG0313 Predicted methyltransferases
[H] COG0314 Molybdopterin converting factor, large subunit
[H] COG0315 Molybdenum cofactor biosynthesis enzyme
[S] COG0316 Uncharacterized conserved protein
[TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases
[IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
[R] COG0319 Predicted metal-dependent hydrolase
[H] COG0320 Lipoate synthase
[H] COG0321 Lipoate-protein ligase B
[L] COG0322 Nuclease subunit of the excinuclease complex
[L] COG0323 DNA mismatch repair enzyme (predicted ATPase)
[J] COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase
[R] COG0325 Predicted enzyme with a TIM-barrel fold
[O] COG0326 Molecular chaperone, HSP90 family
[S] COG0327 Uncharacterized conserved protein
[L] COG0328 Ribonuclease HI
[EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase
[O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs
[I] COG0331 (acyl-carrier-protein) S-malonyltransferase
[I] COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III
[J] COG0333 Ribosomal protein L32
[E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase
[J] COG0335 Ribosomal protein L19
[J] COG0336 tRNA-(guanine-N1)-methyltransferase
[E] COG0337 3-dehydroquinate synthetase
[L] COG0338 Site-specific DNA methylase
[E] COG0339 Zn-dependent oligopeptidases
[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase
[U] COG0341 Preprotein translocase subunit SecF
[U] COG0342 Preprotein translocase subunit SecD
[J] COG0343 Queuine/archaeosine tRNA-ribosyltransferase
[S] COG0344 Predicted membrane protein
[E] COG0345 Pyrroline-5-carboxylate reductase
[E] COG0346 Lactoylglutathione lyase and related lyases
[E] COG0347 Nitrogen regulatory protein PII
[C] COG0348 Polyferredoxin
[J] COG0349 Ribonuclease D
[L] COG0350 Methylated DNA-protein cysteine methyltransferase
[H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
[H] COG0352 Thiamine monophosphate synthase
[L] COG0353 Recombinational DNA repair protein (RecF pathway)
[R] COG0354 Predicted aminomethyltransferase related to GcvT
[C] COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)
[C] COG0356 F0F1-type ATP synthase, subunit a
[M] COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division
[L] COG0358 DNA primase (bacterial type)
[J] COG0359 Ribosomal protein L9
[J] COG0360 Ribosomal protein S6
[J] COG0361 Translation initiation factor 1 (IF-1)
[G] COG0362 6-phosphogluconate dehydrogenase
[G] COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase
[G] COG0364 Glucose-6-phosphate 1-dehydrogenase
[I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
[G] COG0366 Glycosidases
[E] COG0367 Asparagine synthase (glutamine-hydrolyzing)
[H] COG0368 Cobalamin-5-phosphate synthase
[P] COG0369 Sulfite reductase, alpha subunit (flavoprotein)
[P] COG0370 Fe2+ transport system protein B
[C] COG0371 Glycerol dehydrogenase and related enzymes
[C] COG0372 Citrate synthase
[H] COG0373 Glutamyl-tRNA reductase
[C] COG0374 Ni,Fe-hydrogenase I large subunit
[R] COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)
[P] COG0376 Catalase (peroxidase I)
[C] COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases
[OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
[H] COG0379 Quinolinate synthase
[G] COG0380 Trehalose-6-phosphate synthase
[M] COG0381 UDP-N-acetylglucosamine 2-epimerase
[H] COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
[G] COG0383 Alpha-mannosidase
[R] COG0384 Predicted epimerase, PhzC/PhzF homolog
[R] COG0385 Predicted Na+-dependent transporter
[O] COG0386 Glutathione peroxidase
[P] COG0387 Ca2+/H+ antiporter
[R] COG0388 Predicted amidohydrolase
[L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair
[R] COG0390 ABC-type uncharacterized transport system, permease component
[S] COG0391 Uncharacterized conserved protein
[S] COG0392 Predicted integral membrane protein
[S] COG0393 Uncharacterized conserved protein
[T] COG0394 Protein-tyrosine-phosphatase
[G] COG0395 ABC-type sugar transport system, permease component
[O] COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
[S] COG0397 Uncharacterized conserved protein
[S] COG0398 Uncharacterized conserved protein
[M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis
[R] COG0400 Predicted esterase
[S] COG0401 Uncharacterized homolog of Blt101
[FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases
[E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
[E] COG0404 Glycine cleavage system T protein (aminomethyltransferase)
[E] COG0405 Gamma-glutamyltransferase
[G] COG0406 Fructose-2,6-bisphosphatase
[H] COG0407 Uroporphyrinogen-III decarboxylase
[H] COG0408 Coproporphyrinogen III oxidase
[O] COG0409 Hydrogenase maturation factor
[E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
[E] COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
[Q] COG0412 Dienelactone hydrolase and related enzymes
[H] COG0413 Ketopantoate hydroxymethyltransferase
[H] COG0414 Panthothenate synthetase
[L] COG0415 Deoxyribodipyrimidine photolyase
[I] COG0416 Fatty acid/phospholipid biosynthesis enzyme
[L] COG0417 DNA polymerase elongation subunit (family B)
[F] COG0418 Dihydroorotase
[L] COG0419 ATPase involved in DNA repair
[L] COG0420 DNA repair exonuclease
[E] COG0421 Spermidine synthase
[H] COG0422 Thiamine biosynthesis protein ThiC
[J] COG0423 Glycyl-tRNA synthetase (class II)
[D] COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
[O] COG0425 Predicted redox protein, regulator of disulfide bond formation
[C] COG0426 Uncharacterized flavoproteins
[C] COG0427 Acetyl-CoA hydrolase
[P] COG0428 Predicted divalent heavy-metal cations transporter
[R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold
[A] COG0430 RNA 3'-terminal phosphate cyclase
[R] COG0431 Predicted flavoprotein
[S] COG0432 Uncharacterized conserved protein
[R] COG0433 Predicted ATPase
[R] COG0434 Predicted TIM-barrel enzyme
[O] COG0435 Predicted glutathione S-transferase
[E] COG0436 Aspartate/tyrosine/aromatic aminotransferase
[C] COG0437 Fe-S-cluster-containing hydrogenase components 1
[M] COG0438 Glycosyltransferase
[I] COG0439 Biotin carboxylase
[E] COG0440 Acetolactate synthase, small (regulatory) subunit
[J] COG0441 Threonyl-tRNA synthetase
[J] COG0442 Prolyl-tRNA synthetase
[O] COG0443 Molecular chaperone
[EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
[D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division
[R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases
[H] COG0447 Dihydroxynaphthoic acid synthase
[G] COG0448 ADP-glucose pyrophosphorylase
[M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
[O] COG0450 Peroxiredoxin
[MG] COG0451 Nucleoside-diphosphate-sugar epimerases
[H] COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase
[KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
[D] COG0455 ATPases involved in chromosome partitioning
[R] COG0456 Acetyltransferases
[R] COG0457 FOG: TPR repeat
[EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
[O] COG0459 Chaperonin GroEL (HSP60 family)
[E] COG0460 Homoserine dehydrogenase
[F] COG0461 Orotate phosphoribosyltransferase
[FE] COG0462 Phosphoribosylpyrophosphate synthetase
[M] COG0463 Glycosyltransferases involved in cell wall biogenesis
[O] COG0464 ATPases of the AAA+ class
[O] COG0465 ATP-dependent Zn proteases
[O] COG0466 ATP-dependent Lon protease, bacterial type
[T] COG0467 RecA-superfamily ATPases implicated in signal transduction
[L] COG0468 RecA/RadA recombinase
[G] COG0469 Pyruvate kinase
[L] COG0470 ATPase involved in DNA replication
[P] COG0471 Di- and tricarboxylate transporters
[M] COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase
[CE] COG0473 Isocitrate/isopropylmalate dehydrogenase
[P] COG0474 Cation transport ATPase
[P] COG0475 Kef-type K+ transport systems, membrane components
[H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
[GEPR] COG0477 Permeases of the major facilitator superfamily
[T] COG0478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain
[C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit
[J] COG0480 Translation elongation factors (GTPases)
[M] COG0481 Membrane GTPase LepA
[J] COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
[G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family
[O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
[R] COG0486 Predicted GTPase
[R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains
[D] COG0489 ATPases involved in chromosome partitioning
[P] COG0490 Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels
[R] COG0491 Zn-dependent hydrolases, including glyoxylases
[O] COG0492 Thioredoxin reductase
[ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
[LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
[J] COG0495 Leucyl-tRNA synthetase
[R] COG0496 Predicted acid phosphatase
[L] COG0497 ATPase involved in DNA repair
[E] COG0498 Threonine synthase
[H] COG0499 S-adenosylhomocysteine hydrolase
[QR] COG0500 SAM-dependent methyltransferases
[O] COG0501 Zn-dependent protease with chaperone function
[H] COG0502 Biotin synthase and related enzymes
[F] COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins
[F] COG0504 CTP synthase (UTP-ammonia lyase)
[EF] COG0505 Carbamoylphosphate synthase small subunit
[E] COG0506 Proline dehydrogenase
[L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
[C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
[E] COG0509 Glycine cleavage system H protein (lipoate-binding)
[M] COG0510 Predicted choline kinase involved in LPS biosynthesis
[I] COG0511 Biotin carboxyl carrier protein
[EH] COG0512 Anthranilate/para-aminobenzoate synthases component II
[LKJ] COG0513 Superfamily II DNA and RNA helicases
[L] COG0514 Superfamily II DNA helicase
[RTKL] COG0515 Serine/threonine protein kinase
[F] COG0516 IMP dehydrogenase/GMP reductase
[R] COG0517 FOG: CBS domain
[F] COG0518 GMP synthase - Glutamine amidotransferase domain
[F] COG0519 GMP synthase, PP-ATPase domain/subunit
[E] COG0520 Selenocysteine lyase
[H] COG0521 Molybdopterin biosynthesis enzymes
[J] COG0522 Ribosomal protein S4 and related proteins
[R] COG0523 Putative GTPases (G3E family)
[G] COG0524 Sugar kinases, ribokinase family
[J] COG0525 Valyl-tRNA synthetase
[OC] COG0526 Thiol-disulfide isomerase and thioredoxins
[E] COG0527 Aspartokinases
[F] COG0528 Uridylate kinase
[P] COG0529 Adenylylsulfate kinase and related kinases
[P] COG0530 Ca2+/Na+ antiporter
[E] COG0531 Amino acid transporters
[J] COG0532 Translation initiation factor 2 (IF-2; GTPase)
[O] COG0533 Metal-dependent proteases with possible chaperone activity
[V] COG0534 Na+-driven multidrug efflux pump
[R] COG0535 Predicted Fe-S oxidoreductases
[R] COG0536 Predicted GTPase
[FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
[C] COG0538 Isocitrate dehydrogenases
[J] COG0539 Ribosomal protein S1
[F] COG0540 Aspartate carbamoyltransferase, catalytic chain
[U] COG0541 Signal recognition particle GTPase
[O] COG0542 ATPases with chaperone activity, ATP-binding subunit
[HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
[O] COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)
[O] COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1
[R] COG0546 Predicted phosphatases
[E] COG0547 Anthranilate phosphoribosyltransferase
[E] COG0548 Acetylglutamate kinase
[E] COG0549 Carbamate kinase
[L] COG0550 Topoisomerase IA
[L] COG0551 Zn-finger domain associated with topoisomerase type I
[U] COG0552 Signal recognition particle GTPase
[KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
[C] COG0554 Glycerol kinase
[O] COG0555 ABC-type sulfate transport system, permease component
[L] COG0556 Helicase subunit of the DNA excision repair complex
[K] COG0557 Exoribonuclease R
[I] COG0558 Phosphatidylglycerophosphate synthase
[E] COG0559 Branched-chain amino acid ABC-type transport system, permease components
[E] COG0560 Phosphoserine phosphatase
[R] COG0561 Predicted hydrolases of the HAD superfamily
[M] COG0562 UDP-galactopyranose mutase
[F] COG0563 Adenylate kinase and related kinases
[J] COG0564 Pseudouridylate synthases, 23S RNA-specific
[J] COG0565 rRNA methylase
[J] COG0566 rRNA methylases
[C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes
[K] COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)
[P] COG0569 K+ transport systems, NAD-binding component
[K] COG0571 dsRNA-specific ribonuclease
[F] COG0572 Uridine kinase
[P] COG0573 ABC-type phosphate transport system, permease component
[G] COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
[I] COG0575 CDP-diglyceride synthetase
[O] COG0576 Molecular chaperone GrpE (heat shock protein)
[V] COG0577 ABC-type antimicrobial peptide transport system, permease component
[C] COG0578 Glycerol-3-phosphate dehydrogenase
[R] COG0579 Predicted dehydrogenase
[G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)
[P] COG0581 ABC-type phosphate transport system, permease component
[L] COG0582 Integrase
[K] COG0583 Transcriptional regulator
[C] COG0584 Glycerophosphoryl diester phosphodiesterase
[S] COG0585 Uncharacterized conserved protein
[S] COG0586 Uncharacterized membrane-associated protein
[L] COG0587 DNA polymerase III, alpha subunit
[G] COG0588 Phosphoglycerate mutase 1
[T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins
[FJ] COG0590 Cytosine/adenosine deaminases
[ER] COG0591 Na+/proline symporter
[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
[L] COG0593 ATPase involved in DNA replication initiation
[J] COG0594 RNase P protein component
[R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily
[R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)
[MU] COG0597 Lipoprotein signal peptidase
[P] COG0598 Mg2+ and Co2+ transporters
[S] COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit
[P] COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component
[EP] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
[O] COG0602 Organic radical activating enzymes
[R] COG0603 Predicted PP-loop superfamily ATPase
[CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases
[P] COG0605 Superoxide dismutase
[O] COG0606 Predicted ATPase with chaperone activity
[P] COG0607 Rhodanese-related sulfurtransferase
[L] COG0608 Single-stranded DNA-specific exonuclease
[P] COG0609 ABC-type Fe3+-siderophore transport system, permease component
[V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
[H] COG0611 Thiamine monophosphate kinase
[R] COG0612 Predicted Zn-dependent peptidases
[R] COG0613 Predicted metal-dependent phosphoesterases (PHP family)
[P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component
[MI] COG0615 Cytidylyltransferase
[OU] COG0616 Periplasmic serine proteases (ClpP class)
[J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase
[R] COG0618 Exopolyphosphatase-related proteins
[P] COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
[E] COG0620 Methionine synthase II (cobalamin-independent)
[J] COG0621 2-methylthioadenine synthetase
[R] COG0622 Predicted phosphoesterase
[I] COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH)
[E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
[O] COG0625 Glutathione S-transferase
[E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases
[R] COG0627 Predicted esterase
[R] COG0628 Predicted permease
[L] COG0629 Single-stranded DNA-binding protein
[NU] COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis
[T] COG0631 Serine/threonine protein phosphatase
[L] COG0632 Holliday junction resolvasome, DNA-binding subunit
[C] COG0633 Ferredoxin
[F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase
[H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases
[C] COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K
[R] COG0637 Predicted phosphatase/phosphohexomutase
[O] COG0638 20S proteasome, alpha and beta subunits
[T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases
[K] COG0640 Predicted transcriptional regulators
[R] COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
[T] COG0642 Signal transduction histidine kinase
[NT] COG0643 Chemotaxis protein histidine kinase and related kinases
[C] COG0644 Dehydrogenases (flavoproteins)
[R] COG0645 Predicted kinase
[E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain
[G] COG0647 Predicted sugar phosphatases of the HAD superfamily
[L] COG0648 Endonuclease IV
[C] COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7
[C] COG0650 Formate hydrogenlyase subunit 4
[CP] COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit
[O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
[U] COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase)
[HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
[R] COG0655 Multimeric flavodoxin WrbA
[R] COG0656 Aldo/keto reductases, related to diketogulonate reductase
[I] COG0657 Esterase/lipase
[R] COG0658 Predicted membrane metal-binding protein
[P] COG0659 Sulfate permease and related transporters (MFS superfamily)
[R] COG0661 Predicted unusual protein kinase
[G] COG0662 Mannose-6-phosphate isomerase
[R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily
[T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
[E] COG0665 Glycine/D-amino acid oxidases (deaminating)
[R] COG0666 FOG: Ankyrin repeat
[C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)
[M] COG0668 Small-conductance mechanosensitive channel
[H] COG0669 Phosphopantetheine adenylyltransferase
[R] COG0670 Integral membrane protein, interacts with FtsH
[I] COG0671 Membrane-associated phospholipid phosphatase
[P] COG0672 High-affinity Fe2+/Pb2+ permease
[R] COG0673 Predicted dehydrogenases and related proteins
[C] COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit
[L] COG0675 Transposase and inactivated derivatives
[G] COG0676 Uncharacterized enzymes related to aldose 1-epimerase
[M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase
[O] COG0678 Peroxiredoxin
[R] COG0679 Predicted permeases
[C] COG0680 Ni,Fe-hydrogenase maturation factor
[U] COG0681 Signal peptidase I
[M] COG0682 Prolipoprotein diacylglyceryltransferase
[E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
[H] COG0684 Demethylmenaquinone methyltransferase
[E] COG0685 5,10-methylenetetrahydrofolate reductase
[E] COG0686 Alanine dehydrogenase
[E] COG0687 Spermidine/putrescine-binding periplasmic protein
[I] COG0688 Phosphatidylserine decarboxylase
[J] COG0689 RNase PH
[U] COG0690 Preprotein translocase subunit SecE
[O] COG0691 tmRNA-binding protein
[L] COG0692 Uracil DNA glycosylase
[R] COG0693 Putative intracellular protease/amidase
[O] COG0694 Thioredoxin-like proteins and domains
[O] COG0695 Glutaredoxin and related proteins
[G] COG0696 Phosphoglyceromutase
[GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily
[G] COG0698 Ribose 5-phosphate isomerase RpiB
[R] COG0699 Predicted GTPases (dynamin-related)
[S] COG0700 Uncharacterized membrane protein
[R] COG0701 Predicted permeases
[MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases
[E] COG0703 Shikimate kinase
[P] COG0704 Phosphate uptake regulator
[R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)
[U] COG0706 Preprotein translocase subunit YidC
[M] COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase
[L] COG0708 Exonuclease III
[E] COG0709 Selenophosphate synthase
[E] COG0710 3-dehydroquinate dehydratase
[C] COG0711 F0F1-type ATP synthase, subunit b
[C] COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
[C] COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)
[R] COG0714 MoxR-like ATPases
[P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components
[C] COG0716 Flavodoxins
[F] COG0717 Deoxycytidine deaminase
[S] COG0718 Uncharacterized protein conserved in bacteria
[O] COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component
[H] COG0720 6-pyruvoyl-tetrahydropterin synthase
[J] COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit
[E] COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
[C] COG0723 Rieske Fe-S protein
[R] COG0724 RNA-binding proteins (RRM domain)
[P] COG0725 ABC-type molybdate transport system, periplasmic component
[G] COG0726 Predicted xylanase/chitin deacetylase
[R] COG0727 Predicted Fe-S-cluster oxidoreductase
[R] COG0728 Uncharacterized membrane protein, putative virulence factor
[M] COG0729 Outer membrane protein
[R] COG0730 Predicted permeases
[C] COG0731 Fe-S oxidoreductases
[V] COG0732 Restriction endonuclease S subunits
[R] COG0733 Na+-dependent transporters of the SNF family
[P] COG0735 Fe2+/Zn2+ uptake regulation proteins
[I] COG0736 Phosphopantetheinyl transferase (holo-ACP synthase)
[F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases
[G] COG0738 Fucose permease
[M] COG0739 Membrane proteins related to metalloendopeptidases
[OU] COG0740 Protease subunit of ATP-dependent Clp proteases
[M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
[L] COG0742 N6-adenine-specific methylase
[I] COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase
[M] COG0744 Membrane carboxypeptidase (penicillin-binding protein)
[TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
[H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A
[E] COG0747 ABC-type dipeptide transport system, periplasmic component
[P] COG0748 Putative heme iron utilization protein
[L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains
[M] COG0750 Predicted membrane-associated Zn-dependent proteases 1
[J] COG0751 Glycyl-tRNA synthetase, beta subunit
[J] COG0752 Glycyl-tRNA synthetase, alpha subunit
[P] COG0753 Catalase
[E] COG0754 Glutathionylspermidine synthase
[O] COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
[F] COG0756 dUTPase
[E] COG0757 3-dehydroquinate dehydratase II
[LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
[S] COG0759 Uncharacterized conserved protein
[O] COG0760 Parvulin-like peptidyl-prolyl isomerase
[IM] COG0761 Penicillin tolerance protein
[S] COG0762 Predicted integral membrane protein
[M] COG0763 Lipid A disaccharide synthetase
[I] COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases
[E] COG0765 ABC-type amino acid transport system, permease component
[M] COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase
[Q] COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
[M] COG0768 Cell division protein FtsI/penicillin-binding protein 2
[M] COG0769 UDP-N-acetylmuramyl tripeptide synthase
[M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase
[M] COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase
[D] COG0772 Bacterial cell division membrane protein
[M] COG0773 UDP-N-acetylmuramate-alanine ligase
[M] COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase
[F] COG0775 Nucleoside phosphorylase
[L] COG0776 Bacterial nucleoid DNA-binding protein
[I] COG0777 Acetyl-CoA carboxylase beta subunit
[C] COG0778 Nitroreductase
[S] COG0779 Uncharacterized protein conserved in bacteria
[R] COG0780 Enzyme related to GTP cyclohydrolase I
[K] COG0781 Transcription termination factor
[K] COG0782 Transcription elongation factor
[P] COG0783 DNA-binding ferritin-like protein (oxidative damage protectant)
[T] COG0784 FOG: CheY-like receiver
[O] COG0785 Cytochrome c biogenesis protein
[E] COG0786 Na+/glutamate symporter
[M] COG0787 Alanine racemase
[F] COG0788 Formyltetrahydrofolate hydrolase
[K] COG0789 Predicted transcriptional regulators
[R] COG0790 FOG: TPR repeat, SEL1 subfamily
[M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
[L] COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase
[M] COG0793 Periplasmic protease
[M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation
[R] COG0795 Predicted permeases
[M] COG0796 Glutamate racemase
[M] COG0797 Lipoproteins
[P] COG0798 Arsenite efflux pump ACR3 and related permeases
[S] COG0799 Uncharacterized homolog of plant Iojap protein
[G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase
[H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
[R] COG0802 Predicted ATPase or kinase
[P] COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin
[E] COG0804 Urea amidohydrolase (urease) alpha subunit
[U] COG0805 Sec-independent protein secretion pathway component TatC
[J] COG0806 RimM protein, required for 16S rRNA processing
[H] COG0807 GTP cyclohydrolase II
[J] COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)
[M] COG0810 Periplasmic protein TonB, links inner and outer membranes
[U] COG0811 Biopolymer transport proteins
[M] COG0812 UDP-N-acetylmuramate dehydrogenase
[F] COG0813 Purine-nucleoside phosphorylase
[E] COG0814 Amino acid permeases
[M] COG0815 Apolipoprotein N-acyltransferase
[L] COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)
[L] COG0817 Holliday junction resolvasome, endonuclease subunit
[M] COG0818 Diacylglycerol kinase
[K] COG0819 Putative transcription activator
[R] COG0820 Predicted Fe-S-cluster redox enzyme
[I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
[C] COG0822 NifU homolog involved in Fe-S cluster formation
[U] COG0823 Periplasmic component of the Tol biopolymer transport system
[R] COG0824 Predicted thioesterase
[I] COG0825 Acetyl-CoA carboxylase alpha subunit
[O] COG0826 Collagenase and related proteases
[L] COG0827 Adenine-specific DNA methylase
[J] COG0828 Ribosomal protein S21
[O] COG0829 Urease accessory protein UreH
[O] COG0830 Urease accessory protein UreF
[E] COG0831 Urea amidohydrolase (urease) gamma subunit
[E] COG0832 Urea amidohydrolase (urease) beta subunit
[E] COG0833 Amino acid transporters
[ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
[NT] COG0835 Chemotaxis signal transduction protein
[M] COG0836 Mannose-1-phosphate guanylyltransferase
[G] COG0837 Glucokinase
[C] COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A)
[C] COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J)
[NT] COG0840 Methyl-accepting chemotaxis protein
[V] COG0841 Cation/multidrug efflux pump
[V] COG0842 ABC-type multidrug transport system, permease component
[C] COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1
[M] COG0845 Membrane-fusion protein
[K] COG0846 NAD-dependent protein deacetylases, SIR2 family
[L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
[U] COG0848 Biopolymer transport protein
[D] COG0849 Actin-like ATPase involved in cell division
[D] COG0850 Septum formation inhibitor
[D] COG0851 Septum formation topological specificity factor
[C] COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit
[H] COG0853 Aspartate 1-decarboxylase
[H] COG0854 Pyridoxal phosphate biosynthesis protein
[P] COG0855 Polyphosphate kinase
[F] COG0856 Orotate phosphoribosyltransferase homologs
[R] COG0857 BioD-like N-terminal domain of phosphotransacetylase
[J] COG0858 Ribosome-binding factor A
[M] COG0859 ADP-heptose:LPS heptosyltransferase
[M] COG0860 N-acetylmuramoyl-L-alanine amidase
[P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance
[L] COG0863 DNA modification methylase
[K] COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain
[F] COG1001 Adenine deaminase
[V] COG1002 Type II restriction enzyme, methylase subunits
[E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
[M] COG1004 Predicted UDP-glucose 6-dehydrogenase
[C] COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H)
[P] COG1006 Multisubunit Na+/H+ antiporter, MnhC subunit
[C] COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N)
[C] COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M)
[CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
[H] COG1010 Precorrin-3B methylase
[R] COG1011 Predicted hydrolase (HAD superfamily)
[C] COG1012 NAD-dependent aldehyde dehydrogenases
[C] COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit
[C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
[G] COG1015 Phosphopentomutase
[C] COG1017 Hemoglobin-like flavoprotein
[C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
[R] COG1019 Predicted nucleotidyltransferase
[Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins
[Q] COG1021 Peptide arylation enzymes
[I] COG1022 Long-chain acyl-CoA synthetases (AMP-forming)
[G] COG1023 Predicted 6-phosphogluconate dehydrogenase
[I] COG1024 Enoyl-CoA hydratase/carnithine racemase
[O] COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like
[R] COG1026 Predicted Zn-dependent peptidases, insulinase-like
[E] COG1027 Aspartate ammonia-lyase
[IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
[C] COG1029 Formylmethanofuran dehydrogenase subunit B
[O] COG1030 Membrane-bound serine protease (ClpP class)
[C] COG1031 Uncharacterized Fe-S oxidoreductase
[C] COG1032 Fe-S oxidoreductase
[R] COG1033 Predicted exporters of the RND superfamily
[C] COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
[C] COG1035 Coenzyme F420-reducing hydrogenase, beta subunit
[C] COG1036 Archaeal flavoproteins
[C] COG1038 Pyruvate carboxylase
[L] COG1039 Ribonuclease HIII
[R] COG1040 Predicted amidophosphoribosyltransferases
[L] COG1041 Predicted DNA modification methylase
[C] COG1042 Acyl-CoA synthetase (NDP forming)
[M] COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase
[M] COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase
[E] COG1045 Serine acetyltransferase
[O] COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2
[C] COG1048 Aconitase A
[C] COG1049 Aconitase B
[F] COG1051 ADP-ribose pyrophosphatase
[CHR] COG1052 Lactate dehydrogenase and related dehydrogenases
[C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
[R] COG1054 Predicted sulfurtransferase
[P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases
[H] COG1056 Nicotinamide mononucleotide adenylyltransferase
[H] COG1057 Nicotinic acid mononucleotide adenylyltransferase
[R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA
[L] COG1059 Thermostable 8-oxoguanine DNA glycosylase
[HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes
[KL] COG1061 DNA or RNA helicases of superfamily II
[C] COG1062 Zn-dependent alcohol dehydrogenases, class III
[ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
[R] COG1064 Zn-dependent alcohol dehydrogenases
[O] COG1066 Predicted ATP-dependent serine protease
[O] COG1067 Predicted ATP-dependent protease
[C] COG1069 Ribulose kinase
[G] COG1070 Sugar (pentulose and hexulose) kinases
[C] COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
[H] COG1072 Panthothenate kinase
[R] COG1073 Hydrolases of the alpha/beta superfamily
[L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
[R] COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold
[O] COG1076 DnaJ-domain-containing proteins 1
[D] COG1077 Actin-like ATPase involved in cell morphogenesis
[R] COG1078 HD superfamily phosphohydrolases
[R] COG1079 Uncharacterized ABC-type transport system, permease component
[G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
[G] COG1082 Sugar phosphate isomerases/epimerases
[M] COG1083 CMP-N-acetylneuraminic acid synthetase
[R] COG1084 Predicted GTPase
[C] COG1085 Galactose-1-phosphate uridylyltransferase
[MG] COG1086 Predicted nucleoside-diphosphate sugar epimerases
[M] COG1087 UDP-glucose 4-epimerase
[M] COG1088 dTDP-D-glucose 4,6-dehydratase
[M] COG1089 GDP-D-mannose dehydratase
[R] COG1090 Predicted nucleoside-diphosphate sugar epimerase
[M] COG1091 dTDP-4-dehydrorhamnose reductase
[R] COG1092 Predicted SAM-dependent methyltransferases
[J] COG1093 Translation initiation factor 2, alpha subunit (eIF-2alpha)
[R] COG1094 Predicted RNA-binding protein (contains KH domains)
[K] COG1095 DNA-directed RNA polymerase, subunit E'
[J] COG1096 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain)
[J] COG1097 RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)
[J] COG1098 Predicted RNA binding protein (contains ribosomal protein S1 domain)
[R] COG1099 Predicted metal-dependent hydrolases with the TIM-barrel fold
[R] COG1100 GTPase SAR1 and related small G proteins
[R] COG1101 ABC-type uncharacterized transport system, ATPase component
[F] COG1102 Cytidylate kinase
[R] COG1103 Archaea-specific pyridoxal phosphate-dependent enzymes
[E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
[G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
[R] COG1106 Predicted ATPases
[L] COG1107 Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain
[P] COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components
[G] COG1109 Phosphomannomutase
[L] COG1110 Reverse gyrase
[L] COG1111 ERCC4-like helicases
[L] COG1112 Superfamily I DNA and RNA helicases and helicase subunits
[E] COG1113 Gamma-aminobutyrate permease and related permeases
[E] COG1114 Branched-chain amino acid permeases
[E] COG1115 Na+/alanine symporter
[P] COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component
[P] COG1117 ABC-type phosphate transport system, ATPase component
[P] COG1118 ABC-type sulfate/molybdate transport systems, ATPase component
[P] COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA
[PH] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
[P] COG1121 ABC-type Mn/Zn transport systems, ATPase component
[P] COG1122 ABC-type cobalt transport system, ATPase component
[R] COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase
[EP] COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
[E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components
[E] COG1126 ABC-type polar amino acid transport system, ATPase component
[Q] COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component
[G] COG1129 ABC-type sugar transport system, ATPase component
[V] COG1131 ABC-type multidrug transport system, ATPase component
[V] COG1132 ABC-type multidrug transport system, ATPase and permease components
[I] COG1133 ABC-type long-chain fatty acid transport system, fused permease and ATPase components
[GM] COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component
[P] COG1135 ABC-type metal ion transport system, ATPase component
[V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component
[R] COG1137 ABC-type (unclassified) transport system, ATPase component
[O] COG1138 Cytochrome c biogenesis factor
[C] COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain
[C] COG1140 Nitrate reductase beta subunit
[C] COG1141 Ferredoxin
[C] COG1142 Fe-S-cluster-containing hydrogenase components 2
[C] COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)
[C] COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit
[C] COG1145 Ferredoxin
[C] COG1146 Ferredoxin
[C] COG1148 Heterodisulfide reductase, subunit A and related polyferredoxins
[C] COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain
[C] COG1150 Heterodisulfide reductase, subunit C
[C] COG1151 6Fe-6S prismane cluster-containing protein
[C] COG1152 CO dehydrogenase/acetyl-CoA synthase alpha subunit
[C] COG1153 Formylmethanofuran dehydrogenase subunit D
[HI] COG1154 Deoxyxylulose-5-phosphate synthase
[C] COG1155 Archaeal/vacuolar-type H+-ATPase subunit A
[C] COG1156 Archaeal/vacuolar-type H+-ATPase subunit B
[NU] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase