diff --git a/easystacks/pilot.nessi.no/2023.06/eessi-2023.06-eb-4.9.0-2023a.yml b/easystacks/pilot.nessi.no/2023.06/eessi-2023.06-eb-4.9.0-2023a.yml
index 0809201220..b1429501f3 100644
--- a/easystacks/pilot.nessi.no/2023.06/eessi-2023.06-eb-4.9.0-2023a.yml
+++ b/easystacks/pilot.nessi.no/2023.06/eessi-2023.06-eb-4.9.0-2023a.yml
@@ -37,4 +37,8 @@ easyconfigs:
   - ALL-0.9.2-foss-2023a.eb:
   - OSU-Micro-Benchmarks-7.1-1-gompi-2023a.eb
   - GDAL-3.7.1-foss-2023a.eb
+  - snakemake-8.4.2-foss-2023a.eb:
+      # see https://github.com/easybuilders/easybuild-easyconfigs/pull/19646
+      options:
+        from-pr: 19646
   - dask-2023.9.2-foss-2023a.eb
diff --git a/eb_hooks.py b/eb_hooks.py
index 1e7501a194..585b70a899 100644
--- a/eb_hooks.py
+++ b/eb_hooks.py
@@ -209,6 +209,18 @@ def parse_hook_openblas_relax_lapack_tests_num_errors(ec, eprefix):
         raise EasyBuildError("OpenBLAS-specific hook triggered for non-OpenBLAS easyconfig?!")
 
 
+def parse_hook_Pillow_SIMD_harcoded_paths(ec, eprefix):
+    # patch setup.py to prefix hardcoded /usr/* and /lib paths with value of %(sysroot) template
+    # (which will be empty if EasyBuild is not configured to use an alternate sysroot);
+    # see also https://gitlab.com/eessi/support/-/issues/9
+    if ec.name == 'Pillow-SIMD':
+        ec.update('preinstallopts', """sed -i 's@"/usr/@"%(sysroot)s/usr/@g' setup.py && """)
+        ec.update('preinstallopts', """sed -i 's@"/lib@"%(sysroot)s/lib@g' setup.py && """)
+        print_msg("Using custom configure options for %s: %s", ec.name, ec['preinstallopts'])
+    else:
+        raise EasyBuildError("Pillow-SIMD-specific hook triggered for non-Pillow-SIMD easyconfig?!")
+
+
 def parse_hook_pybind11_replace_catch2(ec, eprefix):
     """
     Replace Catch2 build dependency in pybind11 easyconfigs with one that doesn't use system toolchain.
@@ -578,6 +590,7 @@ def inject_gpu_property(ec):
     'CGAL': parse_hook_cgal_toolchainopts_precise,
     'fontconfig': parse_hook_fontconfig_add_fonts,
     'OpenBLAS': parse_hook_openblas_relax_lapack_tests_num_errors,
+    'Pillow-SIMD' : parse_hook_Pillow_SIMD_harcoded_paths,
     'pybind11': parse_hook_pybind11_replace_catch2,
     'Qt5': parse_hook_qt5_check_qtwebengine_disable,
     'UCX': parse_hook_ucx_eprefix,