diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml
index 62d1b9c7..92c9a4f5 100644
--- a/model/Human-GEM.yml
+++ b/model/Human-GEM.yml
@@ -117620,7 +117620,7 @@
           - MAM01836x: 1
       - lower_bound: 0
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000131373 or ENSG00000182591"
+      - gene_reaction_rule: "ENSG00000131373"
       - rxnNotes: ""
       - rxnFrom: "HMRdatabase"
       - eccodes: "4.1.-.-"
@@ -232395,7 +232395,7 @@
           - MAM02766x: 1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000107537"
+      - gene_reaction_rule: "ENSG00000072210"
       - rxnNotes: ""
       - rxnFrom: "Recon3D"
       - eccodes: "1.2.1.48"