diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml
index fc9c2c85..99c23dd0 100644
--- a/model/Human-GEM.yml
+++ b/model/Human-GEM.yml
@@ -225083,7 +225083,7 @@
           - MAM02519e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000144285 or ENSG00000136531 or ENSG00000153253 or ENSG00000007314 or ENSG00000183873 or ENSG00000136546 or ENSG00000196876 or ENSG00000169432 or ENSG00000185313 or ENSG00000168356 or ENSG00000111319 or ENSG00000168447 or ENSG00000162572 or ENSG00000166828 or ENSG00000164588 or ENSG00000138622 or ENSG00000186815 or ENSG00000162341 or ENSG00000102452"
+      - gene_reaction_rule: "ENSG00000144285 or ENSG00000136531 or ENSG00000153253 or ENSG00000007314 or ENSG00000183873 or ENSG00000136546 or ENSG00000196876 or ENSG00000169432 or ENSG00000185313 or ENSG00000168356 or ENSG00000164588 or ENSG00000138622 or ENSG00000186815 or ENSG00000162341 or ENSG00000102452 or (ENSG00000111319 and ENSG00000168447 and ENSG00000166828) or ENSG00000162572"
       - rxnNotes: ""
       - rxnFrom: "Recon3D"
       - eccodes: ""