Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

planning for upgrading in the next 10 days #33

Open
8 tasks
huangyh09 opened this issue Oct 30, 2024 · 1 comment
Open
8 tasks

planning for upgrading in the next 10 days #33

huangyh09 opened this issue Oct 30, 2024 · 1 comment
Assignees

Comments

@huangyh09
Copy link
Collaborator

huangyh09 commented Oct 30, 2024

Some draft tasks, please keep adding:

  • the selection of l value for the spatial weight matrix (needs to be more automated & more intuitive instructions
  • make the z-score method as default (especially for large samples); we may instead mention permutation in the text
  • plotting: local ligand/receptor (single color, e.g., white to red)
  • trying to replace spatialDE with SparseAEH
  • pathway enrichment: make a new function (ideally intro in API): query gene list(s), background gene list, pathway database -> results as data frame (n_pathway - by - columns: total_gene, overlapped_genes, qury_genes, background_mapped_gene, background_upmapped_genes, p-value
  • pathway enrichment plotting: results data above -> figure; x-axis: -log10(p), size: overlapped genes
  • possibly explore another format of the pl.global_plot(), for example, the p-value is mainly binary for now, not very informative for the significant level
  • maybe also consider minimizing the required dependent pkg
@huangyh09
Copy link
Collaborator Author

Any other contributions or contributors are welcome!!

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

3 participants