diff --git a/.github/workflows/build.yaml b/.github/workflows/build.yaml
index 128375b..6f53f1e 100644
--- a/.github/workflows/build.yaml
+++ b/.github/workflows/build.yaml
@@ -4,12 +4,12 @@ on: [push, pull_request]
 
 jobs:
   build:
-
-    runs-on: ubuntu-latest
     strategy:
       matrix:
-        python-version: [3.8]
+        platform: [ ubuntu-latest, macos-latest ]
+        python-version: ["3.8", "3.9", "3.10"]
 
+    runs-on: ${{ matrix.platform }}
     steps:
     - uses: actions/checkout@v2
     - name: Set up Python ${{ matrix.python-version }}
diff --git a/.readthedocs.yaml b/.readthedocs.yaml
index bcd7bc1..2bd1400 100644
--- a/.readthedocs.yaml
+++ b/.readthedocs.yaml
@@ -21,5 +21,5 @@ sphinx:
 python:
   install:
     - requirements: requirements-dev.txt
-    - method: setuptools
+    - method: pip
       path: .
\ No newline at end of file
diff --git a/Makefile b/Makefile
index f1b6e83..644e6bb 100755
--- a/Makefile
+++ b/Makefile
@@ -31,7 +31,7 @@ dev-install_conda:
 
 tests:
 	make pythoncheck
-	$(PYTHON) setup.py test
+	pytest
 
 doc:
 	cd docs  && rm -rf source/api/generated && rm -rf source/gallery &&\
diff --git a/azure-pipelines.yml b/azure-pipelines.yml
index 33cacc7..5e7d229 100644
--- a/azure-pipelines.yml
+++ b/azure-pipelines.yml
@@ -64,7 +64,7 @@ jobs:
     displayName: 'Install prerequisites and library'
 
   - script: |
-      python setup.py test
+      pytest
     condition: succeededOrFailed()
     displayName: 'Run tests'
 
@@ -93,7 +93,7 @@ jobs:
     displayName: 'Install prerequisites and library'
 
   - script: |
-      python setup.py test
+      pytest
     condition: succeededOrFailed()
     displayName: 'Run tests'
 
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 0000000..586db74
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,3 @@
+[build-system]
+requires = ["setuptools", "setuptools-scm"]
+build-backend = "setuptools.build_meta"
\ No newline at end of file
diff --git a/setup.cfg b/setup.cfg
index 6811fdc..33c2c53 100755
--- a/setup.cfg
+++ b/setup.cfg
@@ -1,6 +1,56 @@
+[metadata]
+name = pyproximal
+fullname = PyProximal
+description = Python library implementing proximal operators to solve non-smooth, constrained convex problems with proximal algorithms
+long_description = file: README.md
+long_description_content_type = text/markdown
+author = The PyLops Development Team
+author_email = matteoravasi@gmail.com
+maintainer = "Matteo Ravasi"
+maintainer_email = matteoravasi@gmail.com
+license = LGPL-3.0 License
+license_file = LICENSE.md
+platform = any
+keywords = algebra, inverse problems, proximal, convex optimization, large-scale optimization
+classifiers =
+    Development Status :: 5 - Production/Stable
+    Intended Audience :: Developers
+    Intended Audience :: Science/Research
+    Intended Audience :: Education
+    License :: OSI Approved :: GNU Lesser General Public License v3 (LGPLv3),
+    Natural Language :: English
+    Operating System :: OS Independent
+    Programming Language :: Python :: 3 :: Only
+    Programming Language :: Python :: 3.8
+    Programming Language :: Python :: 3.9
+    Programming Language :: Python :: 3.10
+    Topic :: Scientific/Engineering : Mathematics
+url = https://github.com/pylops/pyproximal
+
+project_urls =
+    Documentation = https://pyproximal.readthedocs.io/
+    Release Notes = https://github.com/pylops/pyproximal/releases
+    Bug Tracker = https://github.com/pylops/pyproximal/issues
+    Source Code = https://github.com/pylops/pyproximal
+
+[options]
+zip_safe = True
+include_package_data = True
+packages = find:
+python_requires = >=3.8
+install_requires =
+    numpy >= 1.15.0
+    scipy >= 1.8.0
+    pylops >= 2.0.0
+
+[options.extras_require]
+advanced =
+    llvmlite
+    numba
+
 [aliases]
 test=pytest
 
 [tool:pytest]
 addopts = --verbose
-python_files = pytests/*.py
\ No newline at end of file
+python_files = pytests/*.py
diff --git a/setup.py b/setup.py
deleted file mode 100644
index d3d6375..0000000
--- a/setup.py
+++ /dev/null
@@ -1,42 +0,0 @@
-import os
-from setuptools import setup, find_packages
-
-def src(pth):
-    return os.path.join(os.path.dirname(__file__), pth)
-
-# Project description
-descr = 'Python library implementing proximal operators to allow solving ' \
-        'non-smooth, constrained convex problems with proximal algorithms.'
-
-# Setup
-setup(
-    name='pyproximal',
-    description=descr,
-    long_description=open(src('README.md')).read(),
-    long_description_content_type='text/markdown',
-    keywords=['algebra',
-              'inverse problems',
-              'proximal',
-              'convex optimization',
-              'large-scale optimization'],
-    classifiers=[
-        'Development Status :: 5 - Production/Stable',
-        'Intended Audience :: Developers',
-        'Intended Audience :: Science/Research',
-        'License :: OSI Approved :: GNU Lesser General Public License v2 or later (LGPLv2+)',
-        'Natural Language :: English',
-        'Programming Language :: Python :: 3.8',
-        'Topic :: Scientific/Engineering :: Mathematics'
-    ],
-    author='mrava',
-    author_email='matteoravasi@gmail.com',
-    install_requires=['numpy >= 1.15.0', 'scipy >= 1.8.0', 'pylops >= 2.0.0'],
-    extras_require={'advanced': ['llvmlite', 'numba']},
-    packages=find_packages(exclude=['pytests']),
-    use_scm_version=dict(root='.',
-                         relative_to=__file__,
-                         write_to=src('pyproximal/version.py')),
-    setup_requires=['pytest-runner', 'setuptools_scm'],
-    test_suite='pytests',
-    tests_require=['pytest'],
-    zip_safe=True)
\ No newline at end of file