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Biological Activity of Suggested Compounds #25

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edwintse opened this issue Jan 31, 2020 · 3 comments
Open

Biological Activity of Suggested Compounds #25

edwintse opened this issue Jan 31, 2020 · 3 comments
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@edwintse
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edwintse commented Jan 31, 2020

We have received the results for the four compounds (#22) that were suggested by the winners of the competition (#18).

@edwintse edwintse added the FYI label Jan 31, 2020
@edwintse
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edwintse commented Feb 26, 2020

UPDATE: We received the potencies for the last two compounds this morning. Unfortunately they were both inactive which is a bit surprising. A by-product (Molomics 2) was also isolated from the reactions when making the Molomics compound which we also had tested. Nevertheless, this should be the last bit of data we need for the paper.

@gcincilla
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@edwintse, a part from the by-product "Molomics 2", did you tested also other by-products? It would be interesting for us to know that, even if they resulted inactive.

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edwintse commented Mar 3, 2020

@gcincilla Yours was the only reaction in which I isolated a by-product during the final steps. More generally though, we have isolated tele-substitution by-products in some reactions (wiki here but needs expanding) and these products are typically inactive.

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