diff --git a/CHANGELOG.md b/CHANGELOG.md
index 4bcd996f3..33311b094 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -4,6 +4,8 @@
 
 * Fixed the suggested rate in `check_regular_timestamps` to be in Hz [#467](https://github.com/NeurodataWithoutBorders/nwbinspector/pull/467)
 
+* Added a skip for mac sidecar files (._*): [#470](https://github.com/NeurodataWithoutBorders/nwbinspector/pull/470)
+
 # v0.4.35
 
 ### Fixes
diff --git a/src/nwbinspector/nwbinspector.py b/src/nwbinspector/nwbinspector.py
index 994ac30df..8f6f89e7c 100644
--- a/src/nwbinspector/nwbinspector.py
+++ b/src/nwbinspector/nwbinspector.py
@@ -395,6 +395,9 @@ def inspect_all(
         in_path = Path(path)
         if in_path.is_dir():
             nwbfiles = list(in_path.rglob("*.nwb"))
+
+            # Remove any macOS sidecar files
+            nwbfiles = [nwbfile for nwbfile in nwbfiles if not nwbfile.name.startswith("._")]
         elif in_path.is_file():
             nwbfiles = [in_path]
         else:
diff --git a/tests/test_inspector.py b/tests/test_inspector.py
index 8fd4808f8..235a5dfcc 100644
--- a/tests/test_inspector.py
+++ b/tests/test_inspector.py
@@ -90,7 +90,7 @@ def setUpClass(cls):
             check_data_orientation,
             check_timestamps_match_first_dimension,
         ]
-        num_nwbfiles = 3
+        num_nwbfiles = 4
         nwbfiles = list()
         for j in range(num_nwbfiles):
             nwbfiles.append(make_minimal_nwbfile())
@@ -100,9 +100,11 @@ def setUpClass(cls):
         add_non_matching_timestamps_dimension(nwbfiles[0])
         add_simple_table(nwbfiles[0])
         add_regular_timestamps(nwbfiles[1])
-        # Last file to be left without violations
+        # Third file to be left without violations
+        add_non_matching_timestamps_dimension(nwbfiles[3])
 
         cls.nwbfile_paths = [str(cls.tempdir / f"testing{j}.nwb") for j in range(num_nwbfiles)]
+        cls.nwbfile_paths[3] = str(cls.tempdir / f"._testing3.nwb")
         for nwbfile_path, nwbfile in zip(cls.nwbfile_paths, nwbfiles):
             with NWBHDF5IO(path=nwbfile_path, mode="w") as io:
                 io.write(nwbfile)