diff --git a/src/cgutils.cpp b/src/cgutils.cpp
index 8e3fb0ee34909..c9beb40a7e474 100644
--- a/src/cgutils.cpp
+++ b/src/cgutils.cpp
@@ -4201,7 +4201,7 @@ static jl_cgval_t emit_new_struct(jl_codectx_t &ctx, jl_value_t *ty, size_t narg
                     fval = boxed(ctx, fval_info, field_promotable);
                     if (!init_as_value) {
                         jl_aliasinfo_t ai = jl_aliasinfo_t::fromTBAA(ctx, ctx.tbaa().tbaa_stack);
-                        ai.decorateInst(ctx.builder.CreateAlignedStore(fval, roots ? roots : dest, Align(jl_field_align(sty, i))));
+                        ai.decorateInst(ctx.builder.CreateAlignedStore(fval, roots ? roots : dest, Align(roots ? sizeof(void*) : jl_field_align(sty, i))));
                     }
                 }
                 else if (jl_is_uniontype(jtype)) {
diff --git a/src/codegen.cpp b/src/codegen.cpp
index d86aa7ba1eb87..68f27fa23d5f0 100644
--- a/src/codegen.cpp
+++ b/src/codegen.cpp
@@ -6187,11 +6187,22 @@ static void emit_upsilonnode(jl_codectx_t &ctx, ssize_t phic, jl_value_t *val)
                 vi.pTIndex, Align(1), true);
         }
         else if (vi.value.V && !vi.value.constant && vi.value.typ != jl_bottom_type) {
-            assert(vi.value.ispointer());
-            Type *T = cast<AllocaInst>(vi.value.V)->getAllocatedType();
-            if (CountTrackedPointers(T).count) {
+            assert(vi.value.inline_roots || vi.value.ispointer());
+            if (vi.value.inline_roots) {
                 // memory optimization: make gc pointers re-initialized to NULL
-                ctx.builder.CreateStore(Constant::getNullValue(T), vi.value.V, true);
+                AllocaInst *ssaroots = cast<AllocaInst>(vi.value.inline_roots);
+                size_t nroots = cast<ConstantInt>(ssaroots->getArraySize())->getZExtValue();
+                auto T_prjlvalue = ssaroots->getAllocatedType();
+                if (auto AT = dyn_cast<ArrayType>(T_prjlvalue)) {
+                    nroots *= AT->getNumElements();
+                    T_prjlvalue = AT->getElementType();
+                }
+                assert(T_prjlvalue == ctx.types().T_prjlvalue);
+                Value *nullval = Constant::getNullValue(T_prjlvalue);
+                auto stack_ai = jl_aliasinfo_t::fromTBAA(ctx, ctx.tbaa().tbaa_stack);
+                for (size_t i = 0; i < nroots; i++) {
+                    stack_ai.decorateInst(ctx.builder.CreateAlignedStore(nullval, emit_ptrgep(ctx, ssaroots, i * sizeof(void*)), ssaroots->getAlign(), true));
+                }
             }
         }
     }
@@ -9598,15 +9609,17 @@ static jl_llvm_functions_t
 
     if (ctx.vaSlot > 0) {
         // remove VA allocation if we never referenced it
+        assert(ctx.slots[ctx.vaSlot].isSA && ctx.slots[ctx.vaSlot].isArgument);
         Instruction *root = cast_or_null<Instruction>(ctx.slots[ctx.vaSlot].boxroot);
         if (root) {
-            Instruction *store_value = NULL;
             bool have_real_use = false;
             for (Use &U : root->uses()) {
                 User *RU = U.getUser();
                 if (StoreInst *SRU = dyn_cast<StoreInst>(RU)) {
-                    if (!store_value)
-                        store_value = dyn_cast<Instruction>(SRU->getValueOperand());
+                    assert(isa<ConstantPointerNull>(SRU->getValueOperand()) || SRU->getValueOperand() == restTuple);
+                }
+                else if (MemSetInst *MSI = dyn_cast<MemSetInst>(RU)) {
+                    assert(MSI->getValue() == ctx.builder.getInt8(0));
                 }
                 else if (isa<DbgInfoIntrinsic>(RU)) {
                 }
@@ -9628,7 +9641,6 @@ static jl_llvm_functions_t
                 if (use)
                     use->eraseFromParent();
                 root->eraseFromParent();
-                assert(!store_value || store_value == restTuple);
                 restTuple->eraseFromParent();
             }
         }
diff --git a/test/compiler/codegen.jl b/test/compiler/codegen.jl
index fa7532c5cc827..f152407ea5b77 100644
--- a/test/compiler/codegen.jl
+++ b/test/compiler/codegen.jl
@@ -501,7 +501,7 @@ function f37262(x)
     end
 end
 @testset "#37262" begin
-    str_opaque = "store volatile { i8, ptr, ptr, ptr, ptr } zeroinitializer, ptr %phic"
+    str_opaque = "getelementptr inbounds i8, ptr %.roots.phic, i32 16\n  store volatile ptr null"
     llvmstr = get_llvm(f37262, (Bool,), false, false, false)
     @test contains(llvmstr, str_opaque)
     @test f37262(Base.inferencebarrier(true)) === nothing