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mutations_in_AML.txt
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mutations_in_AML.txt
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#### mutation type for all genes ####
#for genes with '#not on CGN' the values were determined based on the figure 3 BNM
#and their hypotheical value, so they are not 100 percent accurate
#KITLG= 1 #not on CGN
#FLT3LG= 1 #not on CGN
GRB2= 1
KDM5A= 1
PTEN= 0
#BCR_ABL= 1 #not on CGN
CBLB= 0
CBL= 0 #mixed opinion
#SOS1= 1 #not on CGN
KIT= 1
FLT3= 1
CDK1= 0
STAG2= 0
SH2B3= 0
PTPN6= 0
#AML1_ETO= 1 #not on CGN
#PML_RARalpha= 1 #not on CGN
PTPN11= 1
CUX1= 1 #mixed opinion
RAD21= 0 #not on CGN
BCL2L1= 1
JAK2= 1 #mixed opinion
#CCNA1= 1 #not on CGN
CEBPA= 0
#PIK3IP1= 0 #not on CGN
NRAS= 1
GATA2= 1
BAX= 0
#STAT5A= 1 #not on CGN
#SOX4= 1 #not on CGN
PI3K= 1
#SPI1= 0 #not on CGN
PIM= 1 #mixed opinion
CTNNB1= 1 #mixed opinion
AKT= 1
GATA1= 1 #mixed opinion
#NUP98_Fusion= 0 #not on CGN
MLL_Fusion= 1 #seems to be a fusion of a couple of genes
FOXO= 0 #mixed opinion
EP300= 0
BRAF= 1
CBFB= 0
CDK6= 1
MECOM= 1
#CBFbeta_MYH11= 0 #not on CGN
NPM1= 1
IDH1= 1
IDH2= 1
ERK1/2= 1 #can also be called MAPK1
RUNX1= 0 #mixed opinion
#DOT1L= 1 #not on CGN
FBXW7= 0
#AMPK= 1 #not on CGN
ASXL2= 0
#OXO2= 1 #not on CGN
ETV6= 0
AP1= 1 #also called JUN
DNMT3A= 0
#AEZH2= 0 #not on CGN
ASXL1= 0
MYC= 1
MTOR= 1
TET2= 0
PHF6= 0
CCND1= 1
HOXA9= 1 #mixed opinion
CDKN2A= 0
SRSF2= 1
WT1= 0 #mixed opinion
BCOR= 0
#UBTF= 1 #not on CGN
#MEIS1= 1 #not on CGN
MDM2= 1
U2AF1= 1
XPO1= 1
CREBBP= 0 #mixed opinion
TP53= 0 #mixed opinion
BCL2= 1
#GSK3B = 1 #not on CGN
MAP2K2 = 1 #mixed opinion
NFKB2 = 1 #mixed opinion