Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Redo how we align epitopes with no exact match #47

Open
dmx2 opened this issue Sep 14, 2024 · 0 comments
Open

Redo how we align epitopes with no exact match #47

dmx2 opened this issue Sep 14, 2024 · 0 comments
Assignees
Labels
enhancement New feature or request

Comments

@dmx2
Copy link
Contributor

dmx2 commented Sep 14, 2024

Right now, we are using BLAST for linear epitopes against their parent protein and getting the best hit. For discontinuous epitopes, we are doing a residue-by-residue count. Bjoern suggested aligning the source protein to the parent and then getting sequence identity that way as it should cover more hits for linear epitopes and be more accurate for discontinous.

@dmx2 dmx2 self-assigned this Sep 14, 2024
@dmx2 dmx2 added the enhancement New feature or request label Sep 14, 2024
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
enhancement New feature or request
Projects
None yet
Development

No branches or pull requests

1 participant