Add meeting notes August 9

meeting_notes/2023/20230809_telco.md

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+# QC working group teleconference 9 August 2023
+
+- Chris Bielow
+- Wout Bittremieux
+- Nils Hoffmann
+- Mathias Walzer
+
+---
+
+## Controlled vocabulary
+
+Mathias & Chris will do a final review of [PR206](https://github.com/HUPO-PSI/psi-ms-CV/pull/206) with the MsQuality terms so that it can be merged.
+
+How should we represent spectrum counts in the CV: as absolute counts or relative percentages?
+- The current example relates to the number of MS/MS spectra identified as a contaminant peptide, but this is a more general question as well.
+- QuaMeter has previously used relative ratios.
+- In contrast, ratios can be derived from absolute counts complemented by the total number of spectra.
+- Mathias will reflect on how to best represent this based on how this metric will be used for QC reporting and ask for feedback afterwards.
+As a side note: the relative intensity of contaminants could be an interesting QC metric as well, as they might dominate the measurements when there's a low sample content.
+
+## Software manuscript
+
+Discussion of datasets to be used as an illustration of the mzQC software libraries:
+- Mathias shared QC metrics for the iPRG2015 dataset. However, all runs are extremely alike, making this a very boring dataset. The seemingly interesting BSA contaminants in sample 4 were actually explicitly spiked in.
+- The autoQC dataset that we looked at previously was also too clean.
+- Chris has a few nice examples of failed datasets in his PTXQC paper. He will revisit some of these files to check whether they can be used for our purpose.
+
+## mzQC format manuscript
+
+Mathias has (unpublished) longitudinal data from the CRG team in Barcelona with historical QC runs over a two year period on two different instruments.