diff --git a/src/ontology/disease_drivers.owl b/src/ontology/data_src/disease_drivers.owl similarity index 100% rename from src/ontology/disease_drivers.owl rename to src/ontology/data_src/disease_drivers.owl diff --git a/src/ontology/releases/2023-11-23/disdriv.owl b/src/ontology/releases/2023-11-23/disdriv.owl deleted file mode 100644 index 2d38004..0000000 --- a/src/ontology/releases/2023-11-23/disdriv.owl +++ /dev/null @@ -1,463 +0,0 @@ - - - - - Drivers of human diseases including environmental, maternal and social exposures. - Disease Drivers - - - - - - - - - - - - - - The official definition. - - - - - The official definition. - url:http://purl.obolibrary.org/obo/iao.owl - - - - - - - - Description of the ontology. - description - - - - - Description of the ontology. - url:http://purl.org/dc/elements/1.1/description - - - - - - - - Title of the ontology. - title - - - - - Title of the ontology. - url:http://purl.org/dc/elements/1.1/title - - - - - - - - License of the ontology. - license - - - - - License of the ontology. - url:http://purl.org/dc/terms/license - - - - - - - - Reference database or publication source. - database_cross_reference - - - - - Reference database or publication source. - url:http://www.geneontology.org/formats/oboInOwl#hasDbXref - - - - - - - - has exact synonym - - - - - - - - An identifier for an individual entity. - id - - - - - An identifier for an individual entity. - url:http://purl.obolibrary.org/obo/IAO_0020000 - - - - - - - - A human readable name for this class. - label - - - - - A human readable name for this class. - url:http://www.w3.org/2000/01/rdf-schema#label - - - - - - - - - - - - - part of - - - - - - - - has part - - - - - - - - has role - - - - - - - - - - - - - - A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. - CHEBI:30879 - alcohol - - - - - A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. - url:https://medlineplus.gov/alcohol.html - - - - - - - - - A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. - CHEBI:50904 - allergen - - - - - A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. - url:https://www.niehs.nih.gov/health/topics/agents/allergens/ - - - - - - - - Environmental or genetic mechanisms driving the occurrance of complex diseases. - DISDRIV:0000000 - disease driver - - - - - Environmental or genetic mechanisms driving the occurrance of complex diseases. - url:https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4517741/ - - - - - - - - - A disease driver that is comprised of a shortage of a nutrient. - DISDRIV:0000001 - nutrient deficiency - - - - - A disease driver that is comprised of a shortage of a nutrient. - url:https://www.who.int/health-topics/micronutrients - - - - - - - - - A disease driver that is related to or concerning the interaction of social and economic factors. - DISDRIV:0000002 - socioeconomic driver - - - - - A disease driver that is related to or concerning the interaction of social and economic factors. - url:https://pubmed.ncbi.nlm.nih.gov/29709281/ - - - - - - - - - A disease driver that is of biological origin. - DISDRIV:0000003 - biological driver - - - - - A disease driver that is of biological origin. - url:https://www.ncbi.nlm.nih.gov/books/NBK45737/ - - - - - - - - - A nutrient deficiency of vitamin B7 (biotin) foods like eggs, milk, and bananas. - DISDRIV:0000004 - deficiency of biotin - - - - - A nutrient deficiency of vitamin B7 (biotin) foods like eggs, milk, and bananas. - url:https://ods.od.nih.gov/factsheets/Biotin-Consumer/ - - - - - - - - - A nutrient deficiency. - DISDRIV:0000005 - deficiency of choline - - - - - A nutrient deficiency. - url:https://ods.od.nih.gov/factsheets/Choline-Consumer/ - url:url:https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/ - - - - - - - - - A disease driver that is a chemical. - DISDRIV:0000006 - chemical driver - - - - - A disease driver that is a chemical. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - DISDRIV:0000007 - deficiency of vitamin C - - - - - - - - - An exposure stressor that is a change in the distributions, abundance and relations of organisms and their interactions with the environment. - ExO:0000007 - ecological perturbations - - - - - An exposure stressor that is a change in the distributions, abundance and relations of organisms and their interactions with the environment. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water. - ENVO:03000127 - OMIT:0016047 - ExO:0000013 - acid rain - - - - - An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - url:https://www.epa.gov/acidrain/what-acid-rain - - - - - - - - - An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities. - ExO:0000014 - climate change - - - - - An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level. - ExO:0000015 - poverty - - - - - A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level. - url:https://en.wikipedia.org/wiki/Poverty - url:https://www.un.org/en/global-issues/ending-poverty - url:https://www.worldbank.org/en/topic/poverty/overview - - - - - - - - - An alcoholic drink (or alcoholic beverage) is a drink that contains ethanol, a type of alcohol produced by fermentation of grains, fruits, or other sources of sugar. - FOODON:00001579 - alcoholic beverage - - - - - An alcoholic drink (or alcoholic beverage) is a drink that contains ethanol, a type of alcohol produced by fermentation of grains, fruits, or other sources of sugar. - url:https://en.m.wikipedia.org/wiki/Alcoholic_drink - - - - - - - - - A biological driver that is botulinum toxin, caused by a toxin made by a bacterium called Clostridium botulinum. - NCIT:C163032 - botulinum toxin - - - - - A biological driver that is botulinum toxin, caused by a toxin made by a bacterium called Clostridium botulinum. - url:https://www.osha.gov/botulism - - - - - - - diff --git a/src/ontology/releases/disdriv.owl b/src/ontology/releases/disdriv.owl deleted file mode 100644 index e051d33..0000000 --- a/src/ontology/releases/disdriv.owl +++ /dev/null @@ -1,394 +0,0 @@ - - - - - Disease Drivers - Drivers of human diseases including environmental, maternal and social exposures. - - - - - - - - - - - - - The official definition. - definition - - - - - The official definition. - url:http://purl.obolibrary.org/obo/iao.owl - - - - - - - - Description of the ontology. - description - - - - - Description of the ontology. - url:http://purl.org/dc/elements/1.1/description - - - - - - - - Title of the ontology. - title - - - - - Title of the ontology. - url:http://purl.org/dc/elements/1.1/title - - - - - - - - License of the ontology. - license - - - - - License of the ontology. - url:http://purl.org/dc/terms/license - - - - - - - - Reference database or publication source. - database_cross_reference - - - - - Reference database or publication source. - url:http://www.geneontology.org/formats/oboInOwl#hasDbXref - - - - - - - - Synonym of the term. - has exact synonym - - - - - Synonym of the term. - url:http://www.geneontology.org/formats/oboInOwl#hasExactSynonym - - - - - - - - An identifier for an individual entity. - id - - - - - An identifier for an individual entity. - url:http://purl.obolibrary.org/obo/IAO_0020000 - - - - - - - - A human readable name for this class. - label - - - - - A human readable name for this class. - url:http://www.w3.org/2000/01/rdf-schema#label - - - - - - - - - - - - - part of - - - - - - - - has part - - - - - - - - has role - - - - - - - - - - - - - Disease emergence or outbreaks often occur following a driver. Examples of such drivers include climate and weather, economic development, poverty and social inequality, war and famine, human–wildlife interactions, land use and ecosystem changes. (antecedent conditions) - DISDRIV:0000000 - disease driver - - - - - - - - - A disease driver that is comprised of a shortage of a nutrient. - DISDRIV:0000001 - nutrient deficiency - - - - - A disease driver that is comprised of a shortage of a nutrient. - url:https://www.who.int/health-topics/micronutrients - - - - - - - - - socioeconomic drivers - - - - - - - - - weather driver - - - - - - - - - A nutrient deficiency of vitamin B7 (biotin) foods like eggs, milk, and bananas. - deficiency of biotin - - - - - A nutrient deficiency of vitamin B7 (biotin) foods like eggs, milk, and bananas. - url:https://ods.od.nih.gov/factsheets/Biotin-Consumer/ - - - - - - - - - A nutrient deficiency - deficiency of choline - - - - - A nutrient deficiency - url:https://ods.od.nih.gov/factsheets/Choline-Consumer/ - url:url:https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/ - - - - - - - - - chemical driver - - - - - - - - - An exposure stressor that is a change in the distributions, abundance and relations of organisms and their interactions with the environment. - ExO:0000007 - ecological perturbations - - - - - An exposure stressor that is a change in the distributions, abundance and relations of organisms and their interactions with the environment. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water. - ENVO:03000127 - OMIT:0016047 - ExO:0000013 - acid rain - - - - - An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - url:https://www.epa.gov/acidrain/what-acid-rain - - - - - - - - - An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities. - ExO:0000014 - climate change - - - - - An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level. - ExO:0000015 - poverty - - - - - A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level. - url:https://en.wikipedia.org/wiki/Poverty - url:https://www.un.org/en/global-issues/ending-poverty - url:https://www.worldbank.org/en/topic/poverty/overview - - - - - - - - - A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. - CHEBI:30879 - alcohol - - - - - A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. - url:https://medlineplus.gov/alcohol.html - - - - - - - - - An alcoholic drink (or alcoholic beverage) is a drink that contains ethanol, a type of alcohol produced by fermentation of grains, fruits, or other sources of sugar. - FOODON:00001579 - alcoholic beverage - - - - - An alcoholic drink (or alcoholic beverage) is a drink that contains ethanol, a type of alcohol produced by fermentation of grains, fruits, or other sources of sugar. - url:https://en.m.wikipedia.org/wiki/Alcoholic_drink - - - - - - - diff --git a/src/ontology/releases/disease_drivers.owl b/src/ontology/releases/disease_drivers.owl deleted file mode 100644 index 3f1d069..0000000 --- a/src/ontology/releases/disease_drivers.owl +++ /dev/null @@ -1,2236 +0,0 @@ - - - - - - Disease Drivers - Drivers of human diseases including environmental, maternal and social exposures. - - - - - - - - - - - - - The official definition. - definition - - - - - The official definition. - url:http://purl.obolibrary.org/obo/iao.owl - - - - - - - - Description of the ontology. - description - - - - - Description of the ontology. - url:http://purl.org/dc/elements/1.1/description - - - - - - - - Title of the ontology. - title - - - - - Title of the ontology. - url:http://purl.org/dc/elements/1.1/title - - - - - - - - License of the ontology. - license - - - - - License of the ontology. - url:http://purl.org/dc/terms/license - - - - - - - - Reference database or publication source. - database_cross_reference - - - - - Reference database or publication source. - url:http://www.geneontology.org/formats/oboInOwl#hasDbXref - - - - - - - - Synonym of the term. - has exact synonym - - - - - Synonym of the term. - url:http://www.geneontology.org/formats/oboInOwl#hasExactSynonym - - - - - - - - An identifier for an individual entity. - id - - - - - An identifier for an individual entity. - url:http://purl.obolibrary.org/obo/IAO_0020000 - - - - - - - - A human readable name for this class. - label - - - - - A human readable name for this class. - url:http://www.w3.org/2000/01/rdf-schema#label - - - - - - - - - - - - - - A flame retardant that is hexabromocyclododecane (HBCD), an additive primarily used in polystyrene foam building materials. - CHEBI:134063 - hexabromocyclododecane - - - - - A flame retardant that is hexabromocyclododecane (HBCD), an additive primarily used in polystyrene foam building materials. - url:https://www.niehs.nih.gov/health/topics/agents/flame_retardants/index.cfm - - - - - - - - - A chemical agent that is endocrine disruptor, chemicals that may mimic or interfere with the body’s hormones. Any compound that can disrupt the functions of the endocrine (hormone) system - CHEBI:138015 - endochrine disruptor - - - - - A chemical agent that is endocrine disruptor, chemicals that may mimic or interfere with the body’s hormones. Any compound that can disrupt the functions of the endocrine (hormone) system - url:https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm - - - - - - - - - A vitamin deficiency that is biotin deficiency, a B-complex vitamin, affecting the activity of biotin-dependent carboxylases. - biotin deficiency - - - - - A vitamin deficiency that is biotin deficiency, a B-complex vitamin, affecting the activity of biotin-dependent carboxylases. - url:https://www.ncbi.nlm.nih.gov/books/NBK547751/ - - - - - - - - - An endocrine disruptor that is triclosan, that may be found in some anti-microbial and personal care products, like liquid body wash. - CHEBI:164200 - triclosan - - - - - An endocrine disruptor that is triclosan, that may be found in some anti-microbial and personal care products, like liquid body wash. - url:https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm - - - - - - - - - A solvent that is benzene. - CHEBI:16716 - benzene - - - - - A solvent that is benzene. - url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271273/ - - - - - - - - - A chemical agent that is formaldehyde, a colorless, flammable, strong-smelling chemical widely used to make home building products and commonly used as a preservative in medical laboratories, mortuaries, and consumer products, including some hair smoothing and straightening products. - CHEBI:16842 - formaldehyde - - - - - A chemical agent that is formaldehyde, a colorless, flammable, strong-smelling chemical widely used to make home building products and commonly used as a preservative in medical laboratories, mortuaries, and consumer products, including some hair smoothing and straightening products. - url:https://www.niehs.nih.gov/health/topics/agents/formaldehyde/index.cfm - - - - - - - - - A flame retardant that is brominated flame retardant, contain bromine and are the most abundantly used flame retardants. Used in many consumer goods, including electronics, furniture, building materials, etc. and have been linked to endocrine disruption among other effects. - CHEBI:172368 - brominated flame retardant - - - - - A flame retardant that is brominated flame retardant, contain bromine and are the most abundantly used flame retardants. Used in many consumer goods, including electronics, furniture, building materials, etc. and have been linked to endocrine disruption among other effects. - url:https://www.niehs.nih.gov/health/topics/agents/flame_retardants/index.cfm - - - - - - - - - A chemical agent that is glycol ether. - CHEBI:172390 - glycol ether - - - - - A chemical agent that is glycol ether. - url:https://www.cdc.gov/niosh/docs/83-112/default.html - url:https://www.epa.gov/sites/production/files/2016-09/documents/glycol-ethers.pdf - - - - - - - - - An endocrine disruptor that is perfluoroalkyl substance, used widely in industrial applications, such as firefighting foams and non-stick pan, paper, and textile coatings. - CHEBI:172397 - perfluoroalkyl substance - - - - - An endocrine disruptor that is perfluoroalkyl substance, used widely in industrial applications, such as firefighting foams and non-stick pan, paper, and textile coatings. - url:https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm - - - - - - - - - An endocrine disruptor that is polyfluoroalkyl substance, used widely in industrial applications, such as firefighting foams and non-stick pan, paper, and textile coatings. - CHEBI:172406 - polyfluoroalkyl substance - - - - - An endocrine disruptor that is polyfluoroalkyl substance, used widely in industrial applications, such as firefighting foams and non-stick pan, paper, and textile coatings. - url:https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm - - - - - - - - - A poison that is carbon monoxide (CO), a gas that has no odor or color, can cause sudden illness and death. CO is found in combustion fumes, such as those made by cars and trucks, lanterns, stoves, gas ranges and heating systems. CO from these fumes can build up in places that don't have a good flow of fresh air. You can be poisoned by breathing them in. - CHEBI:17245 - carbon monoxide - - - - - A poison that is carbon monoxide (CO), a gas that has no odor or color, can cause sudden illness and death. CO is found in combustion fumes, such as those made by cars and trucks, lanterns, stoves, gas ranges and heating systems. CO from these fumes can build up in places that don't have a good flow of fresh air. You can be poisoned by breathing them in. - url:https://medlineplus.gov/carbonmonoxidepoisoning.html - url:https://www.cdc.gov/co/faqs.htm - - - - - - - - - A poison that is cyanide. - CHEBI:17514 - cyanide - - - - - A poison that is cyanide. - url:https://emergency.cdc.gov/agent/cyanide/basics/facts.asp - - - - - - - - - A solvent that is toluene. - CHEBI:17578 - toluene - - - - - A solvent that is toluene. - url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539858/ - - - - - - - - - A heavy metal that is cadmium, a soft, malleable, bluish white metal found in zinc ores. - CHEBI:22977 - cadmium - - - - - A heavy metal that is cadmium, a soft, malleable, bluish white metal found in zinc ores. - url:https://www.osha.gov/cadmium - - - - - - - - - A poison that is herbicide. - CHEBI:24527 - herbicide - - - - - A poison that is herbicide. - url:https://medlineplus.gov/ency/article/002838.htm - - - - - - - - - A heavy metal that is lead, is found primarily in old paint, old paint dust, contaminated soil or contaminated drinking water. - CHEBI:25016 - lead - - - - - A heavy metal that is lead, is found primarily in old paint, old paint dust, contaminated soil or contaminated drinking water. - url:https://www.niehs.nih.gov/health/topics/agents/lead/index.cfm - - - - - - - - - A heavy metal that is mercury, is toxic to living organisms, is an odorless, shiny, silver-white liquid that is commonly used in thermometers, barometers and fluorescent light bulbs. - CHEBI:25195 - mercury - - - - - A heavy metal that is mercury, is toxic to living organisms, is an odorless, shiny, silver-white liquid that is commonly used in thermometers, barometers and fluorescent light bulbs. - url:https://www.niehs.nih.gov/health/topics/agents/mercury/index.cfm - - - - - - - - - A flame retardant that is organophosphate flame retardant (OPFR). - CHEBI:25708 - organophosphate flame retardant - - - - - A flame retardant that is organophosphate flame retardant (OPFR). - url:https://www.niehs.nih.gov/health/topics/agents/flame_retardants/index.cfm - - - - - - - - - A poison that is pesticide, any substance used to kill, repel, or control certain forms of plant or animal life that are considered to be pests. Pesticides include herbicides for destroying weeds and other unwanted vegetation, insecticides for controlling a wide variety of insects, fungicides used to prevent the growth of molds and mildew, disinfectants for preventing the spread of bacteria, and compounds used to control mice and rats. - CHEBI:25944 - pesticide - - - - - A poison that is pesticide, any substance used to kill, repel, or control certain forms of plant or animal life that are considered to be pests. Pesticides include herbicides for destroying weeds and other unwanted vegetation, insecticides for controlling a wide variety of insects, fungicides used to prevent the growth of molds and mildew, disinfectants for preventing the spread of bacteria, and compounds used to control mice and rats. - url:https://www.niehs.nih.gov/health/topics/agents/pesticides/index.cfm - - - - - - - - - An endocrine disruptor that is phthalate, used to make plastics more flexible, they are also found in some food packaging, cosmetics, children’s toys, and medical devices. A family of benzene derivatives that are formed by esterification of phthalic acid. Phthalates are added to increase the flexibility and softness of commercial plastics, which are incorporated into a wide variety of consumer goods. Ingested phthalates may exhibit estrogenic or antiandrogenic effects or they may act as endocrine disruptors. - NCIT:C152072 - CHEBI:26092 - phthalate - - - - - An endocrine disruptor that is phthalate, used to make plastics more flexible, they are also found in some food packaging, cosmetics, children’s toys, and medical devices. A family of benzene derivatives that are formed by esterification of phthalic acid. Phthalates are added to increase the flexibility and softness of commercial plastics, which are incorporated into a wide variety of consumer goods. Ingested phthalates may exhibit estrogenic or antiandrogenic effects or they may act as endocrine disruptors. - url:https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm - - - - - - - - - A biological agent that is a biological toxin. Poisonous substance produced by a biological organism such as a microbe, animal or plant. - CHEBI:27026 - toxin - - - - - A biological agent that is a biological toxin. Poisonous substance produced by a biological organism such as a microbe, animal or plant. - url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429496/ - url:https://www.osha.gov/biological-agents - - - - - - - - - A heavy metal that is arsenic, a heavy metal that is poisonous at low concentrations. - NCIT:C28131 - CHEBI:27563 - arsenic - - - - - A heavy metal that is arsenic, a heavy metal that is poisonous at low concentrations. - url:https://www.niehs.nih.gov/health/topics/agents/arsenic/index.cfm - - - - - - - - - A heavy metal that is chromium, a chromium group element atom that has atomic number 24. - CHEBI:28073 - chromium - - - - - A heavy metal that is chromium, a chromium group element atom that has atomic number 24. - url:https://en.wikipedia.org/wiki/Chromium - - - - - - - - - A chemical agent that is acrylamide, a chemical widely used during the manufacturing of paper, dye, and other industrial products. It can also be formed when certain foods are cooked at high temperatures. Food and cigarette smoke are the major sources of acrylamide exposure. A colorless, odorless, crystalline amide that polymerizes rapidly and can form as a byproduct during the heating of starch-rich foods to high temperatures. A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia. - DRON:00723948 - NCIT:C44329 - OMIT:0020033 - CHEBI:28619 - acrylamide - - - - - A chemical agent that is acrylamide, a chemical widely used during the manufacturing of paper, dye, and other industrial products. It can also be formed when certain foods are cooked at high temperatures. Food and cigarette smoke are the major sources of acrylamide exposure. A colorless, odorless, crystalline amide that polymerizes rapidly and can form as a byproduct during the heating of starch-rich foods to high temperatures. A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia. - url:https://www.niehs.nih.gov/health/topics/agents/acrylamide/index.cfm - - - - - - - - - A heavy metal that is thalium, a metallic element first identified and named from the brilliant green line in its flame spectrum. - CHEBI:30440 - thallium - - - - - A heavy metal that is thalium, a metallic element first identified and named from the brilliant green line in its flame spectrum. - url:https://en.wikipedia.org/wiki/Thallium - url:https://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750026.html - - - - - - - - - A poison that is methylmercury. - CHEBI:30785 - methylmercury - - - - - A poison that is methylmercury. - url:https://www.epa.gov/mercury/how-people-are-exposed-mercury#methylmercury - - - - - - - - - A chemical agent that is alcohol. - NCIT:C2190 - CHEBI:30879 - alcohol - - - - - A chemical agent that is alcohol. - url:https://www.niaaa.nih.gov/alcohol-health/overview-alcohol-consumption/moderate-binge-drinking - url:https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/fetal-alcohol-exposure - - - - - - - - - A poison that is potassium chloride (KCl). - CHEBI:32588 - potassium chloride - - - - - A poison that is potassium chloride (KCl). - url:https://pubchem.ncbi.nlm.nih.gov/compound/Potassium-chloride - - - - - - - - - An endocrine disruptor that is bisphenol A (BPA), a chemical produced in large quantities for use primarily in the production of polycarbonate plastics and epoxy resins. A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups. - CHEBI:33216 - bisphenol A - - - - - An endocrine disruptor that is bisphenol A (BPA), a chemical produced in large quantities for use primarily in the production of polycarbonate plastics and epoxy resins. A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups. - url:https://www.niehs.nih.gov/health/topics/agents/sya-bpa/index.cfm - - - - - - - - - A flame retardant that is tetrabromobisphenol A (TBBPA), widely used to make computer circuit boards and electronics. Also used in some textiles and paper, or as an additive in other flame retardants. - CHEBI:33217 - tetrabromobisphenol A - - - - - A flame retardant that is tetrabromobisphenol A (TBBPA), widely used to make computer circuit boards and electronics. Also used in some textiles and paper, or as an additive in other flame retardants. - url:https://www.niehs.nih.gov/health/topics/agents/flame_retardants/index.cfm - - - - - - - - - An endocrine disruptor that is polychlorinated biphenyl (PCB), used to make electrical equipment like transformers, and in hydraulic fluids, heat transfer fluids, lubricants, and plasticizers. - CHEBI:35446 - polychlorinated biphenyl - - - - - An endocrine disruptor that is polychlorinated biphenyl (PCB), used to make electrical equipment like transformers, and in hydraulic fluids, heat transfer fluids, lubricants, and plasticizers. - url:https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm - - - - - - - - - A chemical agent that is diethylstilbestrol (DES), a synthetic form of estrogen. An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. - CHEBI:41922 - diethylstilbestrol - - - - - A chemical agent that is diethylstilbestrol (DES), a synthetic form of estrogen. An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. - url:https://www.cdc.gov/des/consumers/about/index.html - - - - - - - - - A chemical agent that is asbestos, a group of minerals with long, thin fibers. Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements. One of a number of fibrous magnesium and calcium silicate minerals processed for thermal insulation and fireproofing. - NCIT:C284 - CHEBI:46661 - asbestos - - - - - A chemical agent that is asbestos, a group of minerals with long, thin fibers. Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements. One of a number of fibrous magnesium and calcium silicate minerals processed for thermal insulation and fireproofing. - url:https://medlineplus.gov/asbestos.html - - - - - - - - - An endocrine disruptor that is perchlorate, a by-product of aerospace, weapon, and pharmaceutical industries found in drinking water and fireworks. - CHEBI:49706 - percholrate - - - - - An endocrine disruptor that is perchlorate, a by-product of aerospace, weapon, and pharmaceutical industries found in drinking water and fireworks. - url:https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm - - - - - - - - - A biological agent that is an allergen, a substance that causes an allergic reaction. A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. - CHEBI:50904 - allergen - - - - - A biological agent that is an allergen, a substance that causes an allergic reaction. A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. - url:https://www.niehs.nih.gov/health/topics/agents/allergens/ - - - - - - - - - A poison that is a heavy metal, any metallic chemical element that has a relatively high density and is toxic or poisonous at low concentrations. - OMIT:0019292 - CHEBI:5631 - heavy metal - - - - - A poison that is a heavy metal, any metallic chemical element that has a relatively high density and is toxic or poisonous at low concentrations. - url:https://www.lenntech.com/processes/heavy/heavy-metals/heavy-metals.htm#ixzz6s7SaXlej - - - - - - - - - A chemical agent that is poison, any substance that is harmful to your body. - CHEBI:64909 - poison - - - - - A chemical agent that is poison, any substance that is harmful to your body. - url:https://medlineplus.gov/poisoning.html - - - - - - - - - An endocrine disruptor that is phytoestrogen, naturally occurring substances in plants that have hormone-like activity, such as genistein and daidzein that are in soy products, like tofu or soy milk. - CHEBI:76989 - phytoestrogen - - - - - An endocrine disruptor that is phytoestrogen, naturally occurring substances in plants that have hormone-like activity, such as genistein and daidzein that are in soy products, like tofu or soy milk. - url:https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm - - - - - - - - - A chemical agent that is a flame retardant, chemicals that are applied to materials to prevent the start or slow the growth of fire. - CHEBI:79314 - flame retardant - - - - - A chemical agent that is a flame retardant, chemicals that are applied to materials to prevent the start or slow the growth of fire. - url:https://www.niehs.nih.gov/health/topics/agents/flame_retardants/index.cfm - - - - - - - - - An allergen that is a dust mite, microscopic, insect-like pests that commonly live in house dust. They feed on flakes of dead skin, or dander, that are shed by people and pets. These tiny creatures are a big source of allergens and can worsen allergies and asthma. Dust mites can live in mattresses, bedding, upholstered furniture, carpets, and curtains in your home. - DRON:00020118 - dust mite - - - - - An allergen that is a dust mite, microscopic, insect-like pests that commonly live in house dust. They feed on flakes of dead skin, or dander, that are shed by people and pets. These tiny creatures are a big source of allergens and can worsen allergies and asthma. Dust mites can live in mattresses, bedding, upholstered furniture, carpets, and curtains in your home. - url:https://www.niehs.nih.gov/health/topics/agents/allergens/dustmites/index.cfm - - - - - - - - - An allergen that is fecal material. An excreta material which is composed primarily of feces, an excreta consisting of waste products expelled from an animal's digestive tract during defecation. - ENVO:00002003 - fecal material - - - - - An allergen that is fecal material. An excreta material which is composed primarily of feces, an excreta consisting of waste products expelled from an animal's digestive tract during defecation. - url:http://purl.obolibrary.org/obo/ENVO_00002003 - - - - - - - - - An ecological pertubation that is an earthquake. - ENVO:01000677 - earthquake - - - - - An ecological pertubation that is an earthquake. - url:https://www.usgs.gov/natural-hazards/earthquake-hazards/earthquakes - - - - - - - - - An ecological pertubation that is a tsunami. - ENVO:01000689 - tsunami - - - - - An ecological pertubation that is a tsunami. - url:https://en.wikipedia.org/wiki/Tsunami - url:https://oceanservice.noaa.gov/facts/tsunami.html - - - - - - - - - An ecological pertubation that is fire. - url:https://www.fs.fed.us/rm/pubs_int/int_gtr336.pdf - ENVO:01000786 - fire - - - - - - - - - An ecological pertubation that is a thunder storm. An atmospheric storm which occurs in cumulonimbus clouds and during which lightning and thunder occur. - ENVO:01000878 - thunderstorm - - - - - An ecological pertubation that is a thunder storm. An atmospheric storm which occurs in cumulonimbus clouds and during which lightning and thunder occur. - url:http://scienceline.ucsb.edu/getkey.php?key=781 - url:https://www.ready.gov/thunderstorms-lightning - - - - - - - - - A physical agent that is radiation. A process during which energy is emitted or transmitted in the form of waves or particles through space or a material medium. - NPO:1731 - ENVO:01001023 - radiation - - - - - A physical agent that is radiation. A process during which energy is emitted or transmitted in the form of waves or particles through space or a material medium. - url:https://medlineplus.gov/radiationexposure.html - - - - - - - - - An ecological pertubation that is a cyclone. - ENVO:01001297 - cyclone - - - - - An ecological pertubation that is a cyclone. - url:https://en.wikipedia.org/wiki/Cyclone - - - - - - - - - An ecological pertubation that is a tornado. - ENVO:01001482 - tornado - - - - - An ecological pertubation that is a tornado. - url:https://www.nssl.noaa.gov/education/svrwx101/tornadoes/ - - - - - - - - - A chemical agent that is algal bloom. A harmful algal bloom (HAB) occurs when toxin-producing algae grow excessively in a body of water. Algae are microscopic organisms that live in aquatic environments and use photosynthesis to produce energy from sunlight, just like plants. The excessive algal growth, or algal bloom, becomes visible to the naked eye and can be green, blue-green, red, or brown, depending on the type of algae. Arises from a rapid increase or accumulation in the population of algae (typically microscopic) in an aquatic system. - ENVO:02500018 - ENVO:2000004 - algal bloom - - - - - A chemical agent that is algal bloom. A harmful algal bloom (HAB) occurs when toxin-producing algae grow excessively in a body of water. Algae are microscopic organisms that live in aquatic environments and use photosynthesis to produce energy from sunlight, just like plants. The excessive algal growth, or algal bloom, becomes visible to the naked eye and can be green, blue-green, red, or brown, depending on the type of algae. Arises from a rapid increase or accumulation in the population of algae (typically microscopic) in an aquatic system. - url:https://www.niehs.nih.gov/health/topics/agents/algal-blooms/index.cfm - - - - - - - - An agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure receptor during an exposure event. - ExO:0000000 - exposure stressor - - - - - An agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure receptor during an exposure event. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - An agent of biological origin. - ExO:0000005 - biological agent - - - - - An agent of biological origin. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - An agent of chemical origin. - ExO:0000006 - chemical agent - - - - - An agent of chemical origin. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - An exposure stressor that is a change in the distributions, abundance and relations of organisms and their interactions with the environment. - ExO:0000007 - ecological perturbations - - - - - An exposure stressor that is a change in the distributions, abundance and relations of organisms and their interactions with the environment. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - An agent as a source of energy that may cause injury or disease (e.g., noise, vibration, radiation, temperature extremes). - ExO:0000008 - physical agent - - - - - An agent as a source of energy that may cause injury or disease (e.g., noise, vibration, radiation, temperature extremes). - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - An agent that interferes with one's psychological development in and interaction with a social environment. - ExO:0000009 - psychosocial agent - - - - - An agent that interferes with one's psychological development in and interaction with a social environment. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water. - ENVO:03000127 - OMIT:0016047 - ExO:0000013 - acid rain - - - - - An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - url:https://www.epa.gov/acidrain/what-acid-rain - - - - - - - - - An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities. - ExO:0000014 - climate change - - - - - An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities. - url:https://pubmed.ncbi.nlm.nih.gov/29351546/ - - - - - - - - - A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level. - ExO:0000015 - poverty - - - - - A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level. - url:https://en.wikipedia.org/wiki/Poverty - url:https://www.un.org/en/global-issues/ending-poverty - url:https://www.worldbank.org/en/topic/poverty/overview - - - - - - - - - An allergen that is pollen, a fine to coarse powdery substance, is created by certain plants as part of their reproduction process. It can appear from trees in the spring, grasses in the summer, and weeds in the fall. The structure into which a haploid microspore develops; contains a halpoid tube nucleus and two haploid sperm nuclei at maturity. - BTO:0001097 - NCIT:C79660 - OMIT:0012028 - PO:0025281 - FOODON:03420279 - pollen - - - - - An allergen that is pollen, a fine to coarse powdery substance, is created by certain plants as part of their reproduction process. It can appear from trees in the spring, grasses in the summer, and weeds in the fall. The structure into which a haploid microspore develops; contains a halpoid tube nucleus and two haploid sperm nuclei at maturity. - url:https://www.niehs.nih.gov/health/topics/agents/allergens/pollen/index.cfm - - - - - - - - - A psychosocial agent that is healthcare disparitiy (access to healthcare), the timely use of personal health services to achieve the best health outcomes. - GSSO:001616 - healthcare disparity - - - - - A psychosocial agent that is healthcare disparitiy (access to healthcare), the timely use of personal health services to achieve the best health outcomes. - url:https://www.healthypeople.gov/2020/topics-objectives/topic/Access-to-Health-Services - - - - - - - - - A nutrient deficiency that is copper deficiency. - HP:0011967 - copper deficiency - - - - - A nutrient deficiency that is copper deficiency. - url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637704/ - - - - - - - - - A vitamin deficiency that is vitamin B3 (niacin) deficiency. - HP:0100497 - vitamin B3 deficiency - - - - - A vitamin deficiency that is vitamin B3 (niacin) deficiency. - url:https://www.ncbi.nlm.nih.gov/books/NBK557728/ - - - - - - - - - A vitamin deficiency that is malabsorption of vitamin B12. - HP:0200118 - vitamin B12 malabsorption - - - - - A vitamin deficiency that is malabsorption of vitamin B12. - url:https://www.merckmanuals.com/home/disorders-of-nutrition/vitamins/vitamin-b12-deficiency - - - - - - - - - A flame retardant that is polybrominated diphenyl ethers(PBDE), an endocrine disruptor, PBDEs do not chemically bind with the products to which they are added (furniture, electronics, etc.) so they easily release from these products and enter air and dust. PBDEs can lower birth weight/length of children, and impair neurological development. - NCIT:C125231 - polybrominated diphenyl ether - - - - - A flame retardant that is polybrominated diphenyl ethers(PBDE), an endocrine disruptor, PBDEs do not chemically bind with the products to which they are added (furniture, electronics, etc.) so they easily release from these products and enter air and dust. PBDEs can lower birth weight/length of children, and impair neurological development. - url:https://www.niehs.nih.gov/health/topics/agents/flame_retardants/index.cfm - - - - - - - - - url:A blood product that is platelets (thrombocyte) product. - NCIT:C133278 - platelets product - - - - - url:A blood product that is platelets (thrombocyte) product. - https://www.ncbi.nlm.nih.gov/books/NBK539826/ - - - - - - - - - A blood product that is red blood cells (RBC) product. - NCIT:C133280 - red blood cells product - - - - - A blood product that is red blood cells (RBC) product. - url:https://www.ncbi.nlm.nih.gov/books/NBK539826/ - - - - - - - - - A biological agent that is a microorganism, including bacteria, viruses, or fungi. A microscopic organism. The term microorganism may refer to a prokaryote or eukaryote, and may be a unicellular or multicellular organism. All taxonomic kingdoms contain microorganisms. - NCIT:C14329 - microorganism - - - - - A biological agent that is a microorganism, including bacteria, viruses, or fungi. A microscopic organism. The term microorganism may refer to a prokaryote or eukaryote, and may be a unicellular or multicellular organism. All taxonomic kingdoms contain microorganisms. - url:https://www.osha.gov/biological-agents - - - - - - - - - A psychosocial agent that is diet. - NCIT:C15222 - diet - - - - - A psychosocial agent that is diet. - url:https://www.karger.com/Article/FullText/493399 - - - - - - - - - An irritant that is tobacco smoke. Smoke that is emitted from burning tobacco, including cigarette, pipe and cigar, and from tobacco smoke exhaled by smokers. - environmental tobacco smoke - NCIT:C154329 - tobacco smoke - - - - - An irritant that is tobacco smoke. Smoke that is emitted from burning tobacco, including cigarette, pipe and cigar, and from tobacco smoke exhaled by smokers. - url:https://www.cdc.gov/tobacco/data_statistics/fact_sheets/health_effects/effects_cig_smoking/index.htm - url:https://www.ncbi.nlm.nih.gov/pubmed/26043318 - url:https://www.niehs.nih.gov/health/topics/agents/allergens/smoke/index.cfm - - - - - - - - - A nutrient deficiency that is iodine deficiency. - NCIT:C157895 - iodine deficiency - - - - - A nutrient deficiency that is iodine deficiency. - url:https://ods.od.nih.gov/factsheets/Iodine-HealthProfessional/ - - - - - - - - - A deficiency of a necessary nutrient. - NCIT:C157938 - nutrient deficiency - - - - - A deficiency of a necessary nutrient. - url:https://www.who.int/health-topics/micronutrients - - - - - - - - - A nutrient deficiency that is iron deficiency. - NCIT:C158814 - iron deficiency - - - - - A nutrient deficiency that is iron deficiency. - url:https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/iron-deficiency-adults - - - - - - - - - A psychosocial agent that is lifestyle. - NCIT:C16795 - lifestyle - - - - - A psychosocial agent that is lifestyle. - url:https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-018-0982-1 - - - - - - - - - A radiation that is p32, a radioactive isotope of phosphorus. - NCIT:C1698 - p32 - - - - - A radiation that is p32, a radioactive isotope of phosphorus. - url:https://pubchem.ncbi.nlm.nih.gov/compound/Phosphorus-32 - - - - - - - - - A fecal material that is mouse feces. - NCIT:C26415 - mouse feces - - - - - A fecal material that is mouse feces. - url:https://nchh.org/information-and-evidence/learn-about-healthy-housing/health-hazards-prevention-and-solutions/rodents/ - - - - - - - - - A psychosocial agent that is emothional anxiety, characterized by feelings of tension, worried thoughts and physical changes like increased blood pressure. - NCIT:C26696 - emotional anxiety - - - - - A psychosocial agent that is emothional anxiety, characterized by feelings of tension, worried thoughts and physical changes like increased blood pressure. - url:https://www.apa.org/topics/anxiety - - - - - - - - - An allergen that is mold. A very large group of microscopic fungi that live on plant or animal matter. Most are filamentous organisms and produce spores that can be air-, water-, or insect-borne. - NCIT:C28266 - mold - - - - - An allergen that is mold. A very large group of microscopic fungi that live on plant or animal matter. Most are filamentous organisms and produce spores that can be air-, water-, or insect-borne. - url:https://www.niehs.nih.gov/health/topics/agents/mold/index.cfm - - - - - - - - - A vitamin deficiency that is vitamin B1 deficiency, low levels of thiamine (vitamin B1). - NCIT:C34418 - vitamin B1 deficiency - - - - - A vitamin deficiency that is vitamin B1 deficiency, low levels of thiamine (vitamin B1). - url:https://www.ncbi.nlm.nih.gov/books/NBK537204/ - - - - - - - - - A vitamin deficiency that is vitamin C (ascorbic acid) deficiency. - NCIT:C35010 - vitamin C deficiency - - - - - A vitamin deficiency that is vitamin C (ascorbic acid) deficiency. - url:https://www.ncbi.nlm.nih.gov/books/NBK493187/ - - - - - - - - - A psychosocial agent that is stress, a feeling of emotional or physical tension. - NCIT:C35041 - stress - - - - - A psychosocial agent that is stress, a feeling of emotional or physical tension. - url:https://medlineplus.gov/ency/article/003211.htm - - - - - - - - - A psychosocial agent that is peer pressure. - NCIT:C38452 - peer pressure - - - - - A psychosocial agent that is peer pressure. - url:https://en.wikipedia.org/wiki/Peer_pressure - - - - - - - - - A physical agent that is strenuous physical exercise. - NCIT:C16567 - strenuous physical exercise - - - - - A physical agent that is strenuous physical exercise. - url:https://www.cdc.gov/nccdphp/dnpa/physical/pdf/pa_intensity_table_2_1.pdf - - - - - - - - - A chemical agent that is chromium hexavalent compound, a form of the metallic element chromium, is widely used in electroplating, stainless steel production, leather tanning, textile manufacturing, and wood preservation. - NCIT:C44357 - chromium hexavalent compound - - - - - A chemical agent that is chromium hexavalent compound, a form of the metallic element chromium, is widely used in electroplating, stainless steel production, leather tanning, textile manufacturing, and wood preservation. - url:https://www.niehs.nih.gov/health/topics/agents/hex-chromium/index.cfm - - - - - - - - - A physical agent that is noise. - NCIT:C45783 - noise - - - - - A physical agent that is noise. - url:https://medlineplus.gov/noise.html - - - - - - - - - A chemical agent that is solvent. - NCIT:C45790 - solvent - - - - - A chemical agent that is solvent. - url:https://www.chemicalsafetyfacts.org/solvents/ - - - - - - - - - A radiation that is radon, a colorless, odorless radioactive gas. - NCIT:C800 - radon - - - - - A radiation that is radon, a colorless, odorless radioactive gas. - url:https://www.niehs.nih.gov/health/topics/agents/radon/index.cfm - - - - - - - - - A biological toxin that is ricin toxin, a plant toxin produced from castor beans. A phytotoxin and lectin comprised of a homodimer of ricin toxin A and B chains derived from the seeds of Ricinus communis, the castor oil plant, with protein synthesis inhibitory activity and extremely high cytotoxicity. - OMIT:0013190 - NCIT:C809 - ricin toxin - - - - - A biological toxin that is ricin toxin, a plant toxin produced from castor beans. A phytotoxin and lectin comprised of a homodimer of ricin toxin A and B chains derived from the seeds of Ricinus communis, the castor oil plant, with protein synthesis inhibitory activity and extremely high cytotoxicity. - url:https://www.osha.gov/ricin - - - - - - - - - A biological agent that is blood transfusion products. - NCIT:C81304 - blood product - - - - - A biological agent that is blood transfusion products. - url:https://www.ncbi.nlm.nih.gov/books/NBK539826/ - - - - - - - - - A nutrient deficiency that is selenium deficiency, a trace mineral. - NCIT:C825 - selenium deficiency - - - - - A nutrient deficiency that is selenium deficiency, a trace mineral. - url:https://www.ncbi.nlm.nih.gov/books/NBK482260/ - - - - - - - - - A vitamin deficiency that is serum retinol levels of below 28 μg/dL. - NCIT:C85220 - vitamin A deficiency - - - - - A vitamin deficiency that is serum retinol levels of below 28 μg/dL. - url:https://dermnetnz.org/topics/vitamin-a-deficiency/ - - - - - - - - - - A vitamin deficiency that is vitamin B6 (pyridoxine) deficiency. - NCIT:C85221 - vitamin B6 deficiency - - - - - A vitamin deficiency that is vitamin B6 (pyridoxine) deficiency. - url:https://www.ncbi.nlm.nih.gov/books/NBK557436/ - - - - - - - - - A psychosocial agent that is violence. - NCIT:C93214 - violence - - - - - A psychosocial agent that is violence. - url:https://www.apa.org/topics/violence - - - - - - - - - A vitamin deficiency that is vitamin K deficiency. - NCIT:C99108 - vitamin K deficiency - - - - - A vitamin deficiency that is vitamin K deficiency. - url:https://www.ncbi.nlm.nih.gov/books/NBK536983/ - - - - - - - - - A chemical agent that is air pollution, that is composed of a mixture of chemical and particulate matter pollutants in outdoor air, including but not limited to carbon monoxide, ozone, sulfur dixoide, nitrogen dioxide, lead, and fine partiuculate matter. Vehicle emissions, fuel oils and natural gas to heat homes, by-products of manufacturing and power generation, particularly coal-fueled power plants, and fumes from chemical production are the primary sources of human-made air pollution. A pollution process during which particulates or other contaminants are released into a portion of air. - ENVO:02500037 - OMIT:0001823 - air pollution - - - - - A chemical agent that is air pollution, that is composed of a mixture of chemical and particulate matter pollutants in outdoor air, including but not limited to carbon monoxide, ozone, sulfur dixoide, nitrogen dioxide, lead, and fine partiuculate matter. Vehicle emissions, fuel oils and natural gas to heat homes, by-products of manufacturing and power generation, particularly coal-fueled power plants, and fumes from chemical production are the primary sources of human-made air pollution. A pollution process during which particulates or other contaminants are released into a portion of air. - url:https://www.epa.gov/clean-air-act-overview/air-pollution-current-and-future-challenges - url:https://www.niehs.nih.gov/health/topics/agents/air-pollution/index.cfm - - - - - - - - - A nutrient deficiency that is choline deficiency, an essential nutrient needed to synthesize phosphatidylcholine and sphingomyelin, two major phospholipids vital for cell membranes. - choline deficiency - - - - - A nutrient deficiency that is choline deficiency, an essential nutrient needed to synthesize phosphatidylcholine and sphingomyelin, two major phospholipids vital for cell membranes. - url:https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/ - - - - - - - - - An allergen that is a cockroach, a source of indoor allergens. - NCBITaxon:85823 - OMIT:0004368 - cockroaches - - - - - An allergen that is a cockroach, a source of indoor allergens. - url:https://www.niehs.nih.gov/health/topics/agents/allergens/dustmites/index.cfm - - - - - - - - - An endocrine disruptor that is dioxin, are mainly byproducts of industrial practices. They are produced through a variety of incineration processes, including improper municipal waste incineration and burning of trash, and can be released into the air during natural processes, such as forest fires and volcanoes. - NCIT:C442 - OMIT:0005411 - dioxin - - - - - An endocrine disruptor that is dioxin, are mainly byproducts of industrial practices. They are produced through a variety of incineration processes, including improper municipal waste incineration and burning of trash, and can be released into the air during natural processes, such as forest fires and volcanoes. - url:https://www.niehs.nih.gov/health/topics/agents/dioxins/index.cfm - - - - - - - - - A vitamin deficiency that is folic acid deficiency. - OMIT:0006701 - folic acid deficiency - - - - - A vitamin deficiency that is folic acid deficiency. - url:https://www.ncbi.nlm.nih.gov/books/NBK535377/ - - - - - - - - - A diet that is a food deprevation (severe caloric deprivation). - OMIT:0006714 - food deprevation - - - - - - - - - A chemical agent that is an irritant, substances that can trigger allergy- and asthma-like reactions upon exposure. - OMIT:0008624 - irritant - - - - - A chemical agent that is an irritant, substances that can trigger allergy- and asthma-like reactions upon exposure. - url:https://www.niehs.nih.gov/health/topics/agents/allergens/index.cfm - - - - - - - - - A vitamin deficiency that is vitamin B2 (riboflavin) deficiency. - OMIT:0013171 - vitamin B2 deficiency - - - - - A vitamin deficiency that is vitamin B2 (riboflavin) deficiency. - url:https://www.ncbi.nlm.nih.gov/books/NBK525977/ - - - - - - - - - A chemical agent that is volatile organic compound (VOC). - OMIT:0026343 - volatile organic compound - - - - - A chemical agent that is volatile organic compound (VOC). - url:https://www.epa.gov/indoor-air-quality-iaq/volatile-organic-compounds-impact-indoor-air-quality - - - - - - - - - A physical agent that is extreme heat. Temperatures that hover 10 degrees or more above the average high temperature for the region and last for several weeks. - OMIT:0026512 - extreme heat - - - - - A physical agent that is extreme heat. Temperatures that hover 10 degrees or more above the average high temperature for the region and last for several weeks. - url:https://www.cdc.gov/disasters/extremeheat/index.html - url:https://www.washington.edu/uwem/preparedness/know-your-hazards/extreme-heat/ - - - - - - - - - An allergen that is dog dander, may trigger allergy symptoms like sneezing or red, itchy eyes. Pet dander, the source of allergens, is composed of tiny, even microscopic, proteins from flecks of skin shed by pets. Dog allergens are also present in dander, as well as saliva, urine, and blood. Although allergen levels can differ among breeds, all breeds, even hairless dogs, can trigger allergies. - OMIT:0028282 - dog dander - - - - - An allergen that is dog dander, may trigger allergy symptoms like sneezing or red, itchy eyes. Pet dander, the source of allergens, is composed of tiny, even microscopic, proteins from flecks of skin shed by pets. Dog allergens are also present in dander, as well as saliva, urine, and blood. Although allergen levels can differ among breeds, all breeds, even hairless dogs, can trigger allergies. - url:https://www.niehs.nih.gov/health/topics/agents/allergens/pets/index.cfm - - - - - - - - - A physical agent that is ultraviolet light. - ZECO:0000214 - ultraviolet light - - - - - A physical agent that is ultraviolet light. - url:https://www.cancer.org/cancer/cancer-causes/radiation-exposure/uv-radiation.html - - - - - - - - - A chemical agent that is warfarin. - CHEBI:10033 - warfarin - - - - - A chemical agent that is warfarin. - url:https://www.cdc.gov/niosh/npg/npgd0665.html - - - - - - - - - A chemical agent that is aflatoxin, produced by the mold Aspergillus flavus that can grow on corn, peanuts, and other grains. Any of a group of related and highly toxic secondary metabolites (mycotoxins) whose main structural feature is a fused coumarin-bis(dihydrofuran) ring system and which are produced by strains of the moulds Aspergillus flavus or A. parasiticus, together with further metabolites of these mycotoxins. - CHEBI:22271 - aflatoxin - - - - - A chemical agent that is aflatoxin, produced by the mold Aspergillus flavus that can grow on corn, peanuts, and other grains. Any of a group of related and highly toxic secondary metabolites (mycotoxins) whose main structural feature is a fused coumarin-bis(dihydrofuran) ring system and which are produced by strains of the moulds Aspergillus flavus or A. parasiticus, together with further metabolites of these mycotoxins. - url:https://www.cancer.gov/about-cancer/causes-prevention/risk/substances/aflatoxins - url:https://www.fda.gov/animal-veterinary/animal-health-literacy/aflatoxin-poisoning-pets - - - - - - - - - A chemcial agent that is styrene, a colorless, flammable liquid, which has a sweet odor and is highly volatile. Styrene is widely used to make plastics and rubber, which are used to manufacture a variety of products, such as insulation, pipes, automobile parts, printing cartridges, food containers, and carpet backing. - CHEBI:27452 - styrene - - - - - A chemcial agent that is styrene, a colorless, flammable liquid, which has a sweet odor and is highly volatile. Styrene is widely used to make plastics and rubber, which are used to manufacture a variety of products, such as insulation, pipes, automobile parts, printing cartridges, food containers, and carpet backing. - url:https://www.niehs.nih.gov/health/topics/agents/styrene/index.cfm - - - - - - - - - A chemical agent that is carbamazepine, a drug resulting in fetal teratogenic effects. A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant. - CHEBI:3387 - carbamazepine - - - - - A chemical agent that is carbamazepine, a drug resulting in fetal teratogenic effects. A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant. - url:https://pubmed.ncbi.nlm.nih.gov/26329145/ - - - - - - - - - A chemical agent that is persistent organic pollutant (POP). - CHEBI:77853 - persistent organic pollutant - - - - - A chemical agent that is persistent organic pollutant (POP). - url:https://www.epa.gov/international-cooperation/persistent-organic-pollutants-global-issue-global-response - - - - - - - - - A chemical agent that is phenytoin, a drug resulting in birth defects when used maternally during pregnancy. A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5. - dilantin - CHEBI:8107 - phenytoin - - - - - A chemical agent that is phenytoin, a drug resulting in birth defects when used maternally during pregnancy. A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5. - url:https://medlineplus.gov/druginfo/meds/a682022.html - - - - - - - - - A biological agent that is foods, specifically contaminated food or beverages. - FOBI:0001 - food - - - - - A biological agent that is foods, specifically contaminated food or beverages. - url:https://www.osha.gov/foodborne-disease - - - - - - - - - A blood product that is blood plasma. - NCIT:C133266 - plasma product - - - - - A blood product that is blood plasma. - url:https://www.ncbi.nlm.nih.gov/books/NBK539826/ - - - - - - - - - A biological toxin that is botulinum toxin, caused by a toxin made by a bacterium called Clostridium botulinum. - FBbi:00000465 - NCIT:C163032 - botulinum toxin - - - - - A biological toxin that is botulinum toxin, caused by a toxin made by a bacterium called Clostridium botulinum. - url:https://www.osha.gov/botulism - - - - - - - - - A chemical agent that is vitamin E acetate. - NCIT:C2834 - vitamin E acetate - - - - - A chemical agent that is vitamin E acetate. - url:https://www.nejm.org/doi/full/10.1056/NEJMoa1916433 - - - - - - - - - A chemical agent that is a plasticizer. - NCIT:C55826 - plasticizer - - - - - A chemical agent that is a plasticizer. - url:https://en.wikipedia.org/wiki/Plasticizer - url:https://polymer-additives.specialchem.com/selection-guide/plasticizers - - - - - - - - - A chemical agent that is accutane (retinoic acid), a medication primarily used to treat severe acne. - Isotretinoin - NCIT:C603 - accutane - - - - - A chemical agent that is accutane (retinoic acid), a medication primarily used to treat severe acne. - url:https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/018662s059lbl.pdf - - - - - - - - - An allergen that is cat dander, may trigger allergy symptoms like sneezing or red, itchy eyes. Pet dander, the source of allergens, is composed of tiny, even microscopic, proteins from flecks of skin shed by pets. Cat allergens are found in cat saliva, which sticks to fur when cats lick themselves. They are also released by glands in the skin and shed as dander or secreted in the urine of male cats. The allergens are buoyant, which means they easily remain airborne. - DRON:00019407 - NCIT:C84494 - cat dander - - - - - An allergen that is cat dander, may trigger allergy symptoms like sneezing or red, itchy eyes. Pet dander, the source of allergens, is composed of tiny, even microscopic, proteins from flecks of skin shed by pets. Cat allergens are found in cat saliva, which sticks to fur when cats lick themselves. They are also released by glands in the skin and shed as dander or secreted in the urine of male cats. The allergens are buoyant, which means they easily remain airborne. - url:https://www.niehs.nih.gov/health/topics/agents/allergens/pets/index.cfm - - - - - - - - - A chemical agent that is thalidomide. - NCIT:C870 - thalidomide - - - - - A chemical agent that is thalidomide. - url:https://en.wikipedia.org/wiki/Thalidomide - url:https://medlineplus.gov/druginfo/meds/a699032.html - url:https://pubmed.ncbi.nlm.nih.gov/21507989/ - - - - - - - - - A chemical agent that is vitamin deficiency. - EFO:0005878 - vitamin deficiency - - - - - A chemical agent that is vitamin deficiency. - url:https://en.wikipedia.org/wiki/Vitamin_deficiency - - - - - - -