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feat(route): dxy board #17294
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Oct 24, 2024
Successfully generated as following: http://localhost:1200/dxy/bbs/board/46 - Success ✔️<?xml version="1.0" encoding="UTF-8"?>
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<title>神经内外</title>
<link>https://www.dxy.cn/bbs/newweb/pc/category/46</link>
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<title>神经内外</title>
<link>https://www.dxy.cn/bbs/newweb/pc/category/46</link>
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<lastBuildDate>Thu, 24 Oct 2024 22:01:53 GMT</lastBuildDate>
<ttl>5</ttl>
<item>
<title>82岁女性,短期内两次急性脑梗死</title>
<description><p>患者肢体无力1周,言语不清6小时入院,</p><div class="ql-image"><img data-file-center-id="545738356" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/944/0652042895646649481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=%2B9XtWv9460dhIuV6gLWbaGXdGrk%3D" data-h="1332" data-w="3735" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><p>既往患2型糖尿病30年,长期使用甘精胰岛素控制血糖,血糖控制平稳,高血压2级30年,既往口服珍菊降压片,血压平稳,自行停药2年</p><p>急查头核磁如下</p><div class="ql-image"><img data-file-center-id="545736906" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/081/4437398164745649481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=7nfjEEUH29dZSUqhv8vDZOxi8l8%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545736900" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/173/0483637057645649481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=lhH%2BpwUgKw7TjRP2ZDC5zP%2BQVto%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545736919" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/483/4895434513845649481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=oF0Oro2VTVZbi5UDSD6kjwsikMU%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545736909" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/061/4819453658745649481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=s7mT1a1wtOGW5tgZTMVsZsO5OBs%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545736994" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/939/6330192557555649481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=lyXGkVFHgMH79O4UnvAEzSLp4NQ%3D" data-h="1311" data-w="4000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><p>保守治疗,疏血通注射液联合低分子肝素,阿托伐他汀钙,替格瑞洛,中医中药,针灸物理康复治疗20余天后患者可简单对答肢体无力症状改善。回家休养期间长期口服抗血小板聚集,稳定斑块治疗。间隔62天再次出现右侧肢体无力,间断抽搐、持续高热38.0-39.5℃,浅昏迷状态,再次完善头核磁如下</p><div class="ql-image"><img data-file-center-id="545735514" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/606/8887361486354649481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=aUeo0PTuSufbCHANCmY51WpEisc%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545735169" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/544/8670297513524649481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=1upsA8VJPveN%2BDgDGikv63hPXIM%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545735165" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/055/4642249598424649481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=5nqiGG5HZojmv6CnDDgefG3eXKk%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545735140" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/175/2599075553324649481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=eZd0IWXsb51yR8LfWUgisk42g0k%3D" data-h="1309" data-w="3342" data-type="10" referrerpolicy="no-referrer"></div></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51080785</link>
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<pubDate>Thu, 24 Oct 2024 15:02:39 GMT</pubDate>
<author>明天的太阳0568</author>
<category>脑梗死</category>
<category>肢体无力</category>
<category>言语含糊不清</category>
</item>
<item>
<title>分享一例迷走右锁骨下动脉</title>
<description><p class="ql-itemtitle" data-type="caseInfo">病例信息</p><p><br></p><div><div class="ql-image"><img data-resize-w="100%" class="img-full-width" data-file-center-id="542801676" src="https://img1p.dxycdn.com/p/s115/2024/1019/831/4817938334675447481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=xC0z%2BBjLHJVztpBIzFEy3WTOFUk%3D" data-h="4096" data-w="2304" data-type="10" referrerpolicy="no-referrer"></div></div><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545703091" src="https://img1p.dxycdn.com/p/s115/2024/1024/508/8250328786646449481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=5VS4HvOICfztOMiXKQqAof3xMWQ%3D" data-h="3612" data-w="2304" data-type="10" referrerpolicy="no-referrer"></div></div><p class="ql-itemtitle" data-type="discussion">总结与讨论</p><p>迷走右侧锁骨下动脉相对罕见,是临床最常见的主动脉弓畸形,表现为右锁骨下动脉的起源和行程异常,由胚胎时期血管发育的异常所致,主动脉弓血管结构从后至前依次为迷走右锁骨下动脉、左锁骨下动脉及左、右颈总动脉。</p><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545707414" src="https://img1p.dxycdn.com/p/s115/2024/1024/833/6186226101918449481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=Jd4og5k2wtWy2iDjlxhd3b7hFUs%3D" data-h="500" data-w="929" data-type="10" referrerpolicy="no-referrer"></div></div><p>大多数无明显临床症状,一般都是在食道钡餐造影、胸部 CT 或者头颈部 CTA 中偶然发现</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51080577</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51080577</guid>
<pubDate>Thu, 24 Oct 2024 13:52:04 GMT</pubDate>
<author>医生胖子张</author>
<category>迷走右锁骨下动脉</category>
</item>
<item>
<title>出血性脑梗死指南</title>
<description><p>出血性脑梗死指南</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51080477</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51080477</guid>
<pubDate>Thu, 24 Oct 2024 13:19:55 GMT</pubDate>
<author>Sunshine慧宝贝</author>
<category>出血性脑梗死</category>
</item>
<item>
<title>病例分享|61岁女患,意识障碍,结合影像学应该如何诊断?</title>
<description><p>女,63岁。</p><p>主诉:头痛3个月,发热伴意识障碍1周。</p><p>现病史:患者入院前3个月无明显诱因出现头痛,为后枕部胀痛,持续性,伴反应迟钝,记忆力下降。曾就诊于当地医院,完善脑电图见广泛中-重度异常脑电图,考虑自身免疫性脑炎,给予激素冲击,抗病毒等对症治疗后患者头痛症状稍有好转。患者于入院前1周出现意识不清并伴有发热。</p><p>既往史:高血压、糖尿病、乙肝、肺癌切除史(长期服用靶向药物)。</p><p>实验室检查:外院腰椎穿刺,颅内压60mmHg。脑脊液常规:潘氏试验阳性,脑脊液生化:葡萄糖 4.65mmol/L,蛋白1.20g/L,氯 117.5mmol/L。</p><p>入院后完善头部磁共振部分序列如下:</p><div class="ql-image"><img data-file-center-id="545653394" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/019/2194160699796149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=XkzJrWOBFkHcBia9K3%2F4abeEItg%3D" data-h="788" data-w="788" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653398" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/075/6522576000896149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=Kctn7umk8EMSiHqcOrt0CY7WAVM%3D" data-h="801" data-w="801" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653397" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/852/3346851899796149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=qT9TXdvpgPBCbCKO7vSeYVsWWmU%3D" data-h="774" data-w="774" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653399" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/785/2346851899796149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=kQn4qzwc4I2xMEXqxHReJPY7VUM%3D" data-h="792" data-w="792" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653401" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/235/0405799899796149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=Usfg8mF%2F6Rje77qKdEZYSPXEInM%3D" data-h="783" data-w="783" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653396" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/845/4346851899796149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=7EthNDIfmNdmUY%2FvJJfVqyOlRaE%3D" data-h="738" data-w="738" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653395" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/043/4832116300896149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=a9JeqPv8QYL1T7ZQsbeFzh%2BFXuM%3D" data-h="723" data-w="723" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div 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src="https://img1p.dxycdn.com/p/s115/2024/1024/157/0867823740507149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=RyFIsakJ%2F8BFwrka04g%2BtCK%2F45c%3D" data-h="665" data-w="665" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653492" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/102/2992909920507149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=2Xxv0u9%2BTBV%2Bcq3HmSFCDfq8EmQ%3D" data-h="732" data-w="732" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653499" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/474/0658355620507149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=jhVF87yDWl7tfnbPDbFJ05OBkfw%3D" data-h="696" data-w="696" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div 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src="https://img1p.dxycdn.com/p/s115/2024/1024/934/2300621271017149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=zEkiqFWgyn14qv5gSul5ZvXmAOM%3D" data-h="671" data-w="671" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653552" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/907/0401176071017149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=RTmsFawtgw%2FGOMlW0zdDuemGTPw%3D" data-h="666" data-w="666" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653556" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/812/6737139481017149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=DUHOW4MUrllaYDUYHNQgrLBTyDs%3D" data-h="666" data-w="666" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653618" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/579/2302391223417149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=R7GT%2Bq0Gg4mM%2Fmt1zNkk0pk3WCY%3D" data-h="692" data-w="692" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653610" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/888/0460230323417149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=4p4A%2B9nBJfSkS64Q3WibACBsGxQ%3D" data-h="681" data-w="681" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653611" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/969/4494154323417149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=KBy7pZVdb6WGElpS3TRtIHGSCVw%3D" data-h="653" data-w="653" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653614" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/457/2118983223417149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=p%2BExPjTwpqWgBkbIQ7Q6KlAPOts%3D" data-h="645" data-w="645" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653613" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/111/6142100133417149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=t8wosWvEqRsFerNfvfKLJJUKJ1Y%3D" data-h="658" data-w="658" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653615" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/137/0276822323417149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=rjdgR%2F9BjhY2VOzzS8tXvyzpnMk%3D" data-h="631" data-w="631" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653616" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/329/3302391223417149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=L2iGB89u5upyriEPtlaqlv18qiE%3D" data-h="650" data-w="650" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653617" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/617/6142908223417149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=IV%2BWIftPoXgNuw9MTZvkq1jp640%3D" data-h="618" data-w="618" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653663" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/497/0829868535717149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=RY48HJXBOzJ9CsioQSz1jinSEgk%3D" data-h="589" data-w="589" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653664" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/483/4669484635717149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=M7Ot5jx3AzjXHz72WwrmvlplUBY%3D" data-h="602" data-w="602" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653670" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/394/8803976755717149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=L0KHBvMomLu%2FTa2EkcRROXx1gME%3D" data-h="716" data-w="716" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653667" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/835/3365270575717149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=SzIM5SpGn2LkTEYPlEEGCIiOiEY%3D" data-h="667" data-w="667" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653666" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/319/2365270575717149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=PAI8R1XH5lTrEbn2X91uiNNBFug%3D" data-h="712" data-w="712" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653665" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/365/4458033675717149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=K8EHpSXKdFWbMSnkLOplXLn%2BwnI%3D" data-h="738" data-w="738" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653668" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/563/2952070975717149481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=p0UtbJv%2F4xYL00oeLN23jr9b9LE%3D" data-h="820" data-w="820" data-type="10" referrerpolicy="no-referrer"></div><p>请结合影像学及患者病史,分析患者诊断思路。期待评论区各位老师高见~</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51080115</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51080115</guid>
<pubDate>Thu, 24 Oct 2024 11:47:36 GMT</pubDate>
<author>青鹊词</author>
<category>头痛</category>
<category>意识模糊</category>
<category>发热</category>
</item>
<item>
<title>这种脑梗倾向溶栓吗</title>
<description><p><br></p><div class="ql-image"><img data-file-center-id="545628887" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/193/0067757044562049481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=ebeScS8%2BEss0C77YwNQRtEp8tD4%3D" data-h="4284" data-w="5712" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545631135" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/605/0631994507693049481.jpg?Expires=1729810911&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=AVT%2FrhmgQ3lWTKigJxB3umU%2FhgE%3D" data-h="3928" data-w="3744" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><p>一个有图1上这么多病的75岁男病人,2月前冠脉搭桥,因双眼凝视、失语及右侧肢体、左下肢肌力1级2小时入院,发病前生活可自理。这种病人倾向于溶栓吗</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51079985</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51079985</guid>
<pubDate>Thu, 24 Oct 2024 10:51:15 GMT</pubDate>
<author>晒太阳的韭菜</author>
<category>脑梗死</category>
</item>
<item>
<title>星期二门诊见闻(314):出个小试题:这张片子能发现哪些异常?</title>
<description><p class="ql-itemtitle" data-type="caseInfo">病例信息</p><p><br></p><div class="ql-image"><img data-file-center-id="545610731" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/594/0253233919922939481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=pHwzJWWshJrI6MbK19XDGCdnPEs%3D" data-h="790" data-w="3058" data-type="10" referrerpolicy="no-referrer"></div><p><strong>小试题:提示哪些异常?</strong></p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51079841</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51079841</guid>
<pubDate>Thu, 24 Oct 2024 10:08:51 GMT</pubDate>
<author>FangQU</author>
</item>
<item>
<title>阿尔茨海默病:从基础到临床2021.10版</title>
<description><p>阿尔茨海默病:从基础到临床2021.10版</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51079363</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51079363</guid>
<pubDate>Thu, 24 Oct 2024 08:15:58 GMT</pubDate>
<author>医学书屋</author>
<category>阿尔茨海默症</category>
</item>
<item>
<title>中国偏头痛急性期治疗指南(第一版)</title>
<description><p>近年来,偏头痛的治疗策略不断规范更新,然而国内在偏头痛急性期治疗实践中仍面临一系列挑战,包括药物选择不当、治疗不足或使用过度、安全性与耐受性不佳等,以及对特定人群、特殊类型偏头痛急性期治疗规范仍相对匮乏。为此,由中国医师协会神经内科医师分会、中国研究型医院学会头痛与感觉障碍专业委员会共同组织编写制订本指南,对《中国偏头痛诊治指南(2022 版)》中的急性期治疗进行补充与更新,针对偏头痛药物和非药物治疗、偏头痛持续状态及特殊人群的急性期管理策略进行详细阐述,旨在进一步提升偏头痛急性期治疗效率。</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51079298</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51079298</guid>
<pubDate>Thu, 24 Oct 2024 08:01:10 GMT</pubDate>
<author>兰亭序1990</author>
<category>偏头痛</category>
</item>
<item>
<title>中国偏头痛急性期治疗指南</title>
<description><p>中国偏头痛急性期治疗指南(第一版)</p><p>近年来,偏头痛的治疗策略不断规范更新,然而国内在偏头痛急性期治疗实践中仍面临一系 列挑战,包括药物选择不当、治疗不足或使用过度、安全性与耐受性不佳等,以及对特定人群、特殊 类型偏头痛急性期治疗规范仍相对匮乏。为此,由中国医师协会神经内科医师分会、中国研究型医院 学会头痛与感觉障碍专业委员会共同组织编写制订本指南,对《中国偏头痛诊治指南(2022 版)》中 的急性期治疗进行补充与更新,针对偏头痛药物和非药物治疗、偏头痛持续状态及特殊人群的急性期 管理策略进行详细阐述,旨在进一步提升偏头痛急性期治疗效率。</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51079251</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51079251</guid>
<pubDate>Thu, 24 Oct 2024 07:49:07 GMT</pubDate>
<author>borisdoctor1971</author>
<category>偏头痛</category>
</item>
<item>
<title>中国偏头痛急性期治疗指南(第一版)_中国医师协会神经内科医师分会_</title>
<description><p>中国偏头痛急性期治疗指南(第一版)_中国医师协会神经内科医师分会_</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51078876</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51078876</guid>
<pubDate>Thu, 24 Oct 2024 06:03:43 GMT</pubDate>
<author>yzb4062073</author>
<category>偏头痛</category>
</item>
<item>
<title>面神经炎使用激素的求助</title>
<description><p>菜鸟新人医生求问,今天新收了一个面神经炎的病人,但是既往是有急性淋巴细胞性白血病的,长期使用长春新碱化疗治疗,这种情况可使用10mg地塞米松抗炎治疗嘛?<img class="ql-expression" src="https://assets.dxycdn.com/app/bbs/emotions/dxmm/01.png" referrerpolicy="no-referrer"></p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51078722</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51078722</guid>
<pubDate>Thu, 24 Oct 2024 05:08:26 GMT</pubDate>
<author>聚窟洲振刀怪</author>
<category>面神经麻痹</category>
</item>
<item>
<title>左下肢麻木就这么简单吗?</title>
<description><p>患者女性,63 岁,主因“双下肢麻木 3 月余,伴双下肢无力 2 月余”于 2024年 05 月 24 日入院。</p><p>现病史:患者缘于 3 月前出现左下肢麻木,就诊于当地医院,考虑为“脑血管病”并给予抗血小板、调脂固斑、改善循环等治疗,症状未见好转,并逐渐出现右下肢麻木,无明显肢体疼痛,无踩棉花感,无二便障碍,无间断性跛行。2 个月前患者出现双下肢无力,行走缓慢,但尚可独立行走,就诊于当地医院,查肌电图示多发周围神经损害(无具体结果),诊断为“糖尿病周围神经病”,未给予特殊治疗,后患者下肢无力进行性加重,逐渐进展至需借助支具行走,为求进一步诊治就诊于我院,并收入院治疗。患者自发病以来精神、饮食尚可,二便正常,无发热,否认前驱感染史,体重无减轻。</p><p>既往史:2008 年 1 月因“腹痛”就诊于我院,诊断为急性胰腺炎,行剖腹探查术及腹腔引流术,术后恢复顺利;2008 年 7 月因“腰痛伴右下肢疼痛憋胀”就诊于外院,行腰椎 MR 示腰椎 4-5 椎体异常信号,考虑炎性改变,腰椎 CT 考虑腰 4-5 椎体结核,腰 4-5 椎间盘突出,行腹膜外腰 4-5 椎间隙探查术,椎间盘及骨质活检考虑“(腰 4-5)急、慢性炎症”,诊断为“腰 4-5 椎间盘炎”,术 后卧床休养;2008 年 9 月因“持续性头痛 1 月”入住我院,头颅 MRI 示:右侧顶枕叶和左侧颞叶可见长 T1,长 T2 信号,MRV 未见异常,行腰穿脑脊液压力 140mmH2O,CSF 常规正常,CSF 生化 Pro 0.6g/L,细胞学仅见 4 个淋巴细胞,脑脊液囊虫试验(+),住院试用吡喹酮出现头部剧痛,考虑脑囊虫可能,期间家属曾于北京询专家会诊,考虑不能除外脑膜癌,后因故自动出院;2018 年 10 月于外院行脑组织活检,病理回报考虑炎性病变(具体不详),家属诉住院治疗后(药物不详)出现病情加重、昏迷,自动出院休养后自愈,未规律服用特殊药物;甲状腺功能减退病史 10 年,平素口服“优甲乐”治疗,控制不佳,未规律复查;糖尿病病史 5 年,平素口服“阿卡波糖、二甲双胍格列本脲”,未规律监测;高血压病史5 年,最高血压不详,平素口服“苯磺酸左氨氯地平、酒石酸美托洛尔”控制,未规律监测;高脂血症 5 年,平素口服“非诺贝特”。否认肝炎、结核等传染病病史,否认食物、药物过敏史。</p><p>个人史及家族史:生于原籍,久居当地,未到过疫区、牧区,无烟酒嗜好,否认毒物及有害物质接触史,否认性病、冶游史。适龄结婚,配偶及孩子体健。</p><p>月经史:初潮&nbsp;14 岁,月经周期 4-5/26-28,52 岁绝经。</p><p>一般体格检查:T 36.5℃ P 55 次/分 R 17 次/分 BP 150/92mmHg,发育正常,营</p><p>养中等,双肺呼吸音清,未闻及干湿性啰音,心率 55 次/分,律齐,未闻及杂音,</p><p>腹软,无压痛及肌紧张,双下肢无指凹性水肿。</p><p>神经系统查体:神清,高级皮层功能正常,语利,双瞳孔正大等圆,直径 3.0mm,</p><p>眼球各方向运动自如,无眼震。双侧额纹对称,无鼻唇沟变浅,伸舌不偏。双上</p><p>肢近端肌力 4-级,远端肌力 4+级,双下肢肌力 4-级,四肢肌张力正常。双上肢</p><p>腱反射未引出,双下肢腱反射(++),双侧巴氏征(+)。感觉系统查体:C4 平面</p><p>以下针刺觉、振动觉减退。共济运动查体欠配合。颈抵抗(-)。</p><p>入院后辅助检查:血常规:WBC 8.60*109/L,NE% 75.04%,Hb 103g/L(115-150),MCV 101.2fl(82-100),PLT 213*109/L;余尿便常规大致正常。生化全项:Urea 9.90mmol/L(3.1-8.8),Cr 162.0μmol/L(41-81),β2 MG:5.10mg/L(1.3-3.0),TG:2.45mmol/L(0.56-1.7),LDL-C 1.17mmol/L(2.07-3.37),GLU8.78mmol/L,Hcy:23.43μmol/L;余肝功能、电解质未见异常。凝血功能:D-Dimer 0.26μg/ml(0-0.243)。代谢+免疫:s-TSH 23.771mIU/L(0.55-4.78),FT3:2.71pmol/L(3.5-6.5),An-TPOAb:>1300IU/ml(<60),An-TGAb:203.40IU/ml(<4.5)。HbA1C:8.4%。自身抗体:ANA(+)胞浆型+颗粒 1:100,VitD:42.10nmol/L(>50),余抗中性粒细胞胞浆抗体、抗磷脂抗体、CRP、血沉、甲状旁腺激素、免疫球蛋白、风湿四项、曲霉菌免疫学实验、术前四项未见明显异常。颅脑 CT:1.考虑右侧颞顶枕叶软化灶伴少许出血;2.脑萎缩。胸部 CT:1.两肺多发结节;2.两肺下叶条片影,考虑炎性或少许肺组织膨胀不良;3.两侧胸膜局部增厚;4.肺动脉主干增宽;5.主动脉及冠状动脉硬化。腹部 CT:1.胰头部饱满,体尾部显示欠清;2.肝脏稍增大;3.胆囊结石;4.上腹前部中线区腹壁薄弱,局部脂肪疝入腹壁;5.左肾稍小,左肾后缘低密度影,直径约 0.8cm,CT 值约 0-40HU;6.腰 4-5 椎体骨性融合。颅脑 MR 平扫+SWI:1.右侧颞枕叶多发异常信号 2.余幕上脑质多发异常信号,部分为腔隙性梗死灶,部分为非特异性脑白质病变,符合 FSⅠ级改变;3.老年脑改变。颅脑 MR 增强:1.符合右顶部术后改变,请结合病史;2.右侧颞顶枕叶多发环形强化结节伴脑膜强化,考虑慢性炎性肉芽肿病变。颈髓 MR 平扫:1.颈 2-7 椎体水平脊髓异常信号,性质待定;2.颈椎生理曲度变直,轻度骨质增生,颈椎间盘变性;3.颈 3-4 椎间盘水平黄韧带增厚。颈髓 DWI:颈髓增粗,可见散在点片状&nbsp;DWI 高信号,ADC 范围较大,呈高信号。
颈髓 MR 增强:1.颈 2-7 椎体水平髓内及脊膜异常强化,结合颅脑检查,考虑炎
性改变;2.颈椎轻度骨质增生,生理曲度变直。
胸髓 MR 平扫:1.胸髓 MR 平扫未见明显异常;2.胸椎骨质增生。
腰椎穿刺:脑脊液压力 120mmH2O
CSF 常规:总细胞 1018*10
6
/L,白细胞 17*10
6
/L(穿刺伤)。
</p><p>CSF 生化:PRO 1.16g/L(0.15-0.45)。
</p><p>血清 AQP4 抗体:阳性(+)1:100。
</p><p>脑脊液 AQP4 抗体:阳性(+)1:100;
</p><p>脑脊液抗 GFAP 抗体:阳性(+)1:32。
</p><p>血清+脑脊液寡克隆区带:Ⅳ型,无鞘内合成,存在外周 B 细胞免疫反应,且伴
有血脑屏障破坏;脑脊液 IgG 指数升高;IgG 24h 鞘内合成率升高。
PDD 试验:阴性。
为明确诊断,于 2024-06-05 行右侧枕叶病灶切除术及组织活检</p><div class="ql-image"><img data-file-center-id="545409656" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/081/4287932552885929481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=9OD3aRBuA4z1GDtPJp8km5TljlA%3D" data-h="791" data-w="1080" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545409657" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/054/6313210642885929481.jpg?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=wF37qsy1OIKYyvU92vUsoKlNti8%3D" data-h="791" data-w="1080" data-type="10" referrerpolicy="no-referrer"></div><p>请各位分析:</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51078340</link>
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<pubDate>Thu, 24 Oct 2024 03:44:59 GMT</pubDate>
<author>理性人</author>
<category>糖尿病性周围神经病</category>
<category>下肢麻木</category>
<category>双下肢无力</category>
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<title>烟雾血管病外科手术学</title>
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<title>病因讨论</title>
<description><p class="ql-itemtitle" data-type="caseInfo">病例信息</p><p><strong>【患者信息】</strong>:男38岁</p><p><strong>【主诉】</strong>:左侧肢体间断麻木1个月。</p><p><strong>【现病史及既往史】</strong>:该患者一个月以来左侧肢体间断麻木,以小拇指、食指和脚底为著,伴有左小腿僵硬。既往高血压病史1年,血压最高152/95mmHg。无糖尿病病史。一个前发现谷丙转氨酶升高156。脂肪肝病史6年。</p><p><strong>【检查】</strong>:头部磁共振:右侧M1和A1起始部狭窄。颈椎磁共振:颈5.6椎间盘突出。</p><p><strong>【临床诊断】</strong>:脑动脉狭窄、颈椎间盘突出</p><p><strong>【治疗经过及结果】</strong>:</p></description>
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<pubDate>Wed, 23 Oct 2024 09:52:34 GMT</pubDate>
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<item>
<title>Neuroprotection|神经退行性疾病中的小胶质细胞衰老:见解、影响和治疗机会</title>
<description><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545049566" src="https://img1p.dxycdn.com/p/s115/2024/1023/185/4686996926733109481.png?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=rf%2F%2B8qd4YpMm4ti6ZMx2%2FYffnWs%3D" data-h="242" data-w="621" data-type="10" referrerpolicy="no-referrer"></div></div><p class="ql-align-center" style="text-align:center"><strong style="color:rgb( 247 , 100 , 100 )"><a class="ql-link" href="https://onlinelibrary.wiley.com/doi/10.1002/nep3.56?msockid=28c2e734863762150015f364877463f4" target="_blank" rel="noopener noreferrer">点击此处</a>即可免费获取论文原文</strong></p><p>本文系统地探讨了小胶质细胞衰老在神经退行性疾病中的作用。首先,文章概述了小胶质细胞的特点,包括其源于卵黄囊、在神经系统中的多种功能等。其次,文章详细介绍了小胶质细胞衰老的特征,如细胞周期永久停滞、分泌senescence相关分泌表型(SASP)以及铁过载等,这些特点可作为其衰老表型的标志。其次,文章重点探讨了小胶质细胞衰老在多种神经退行性疾病中的作用,如阿尔兹海默病、帕金森病、亨廷顿病和肌萎缩性侧索硬化。研究发现,这些疾病中都观察到衰老小胶质细胞的增加,并可能参与了疾病的发生发展。最后,文章提出了靶向小胶质细胞衰老的潜在治疗策略,包括利用铁螯合剂和抗衰老药物等,这为治疗老年性神经退行性疾病提供了新的思路。总的来说,本文系统阐述了小胶质细胞衰老在神经退行性疾病中的重要作用,为深入探索这一领域提供了重要的理论基础。</p><p><strong style="color:rgb( 80 , 159 , 233 )">亮点</strong></p><p class="ql-align-justify">1.&nbsp;深入探讨了小胶质细胞衰老在神经退行性疾病发病机制中的作用。现有研究表明,衰老小胶质细胞在阿尔兹海默病、帕金森病、亨廷顿病和肌萎缩性侧索硬化等疾病中均有增加,这可能是这些疾病发生发展的重要因素。</p><p class="ql-align-justify">2.&nbsp;系统总结了衰老小胶质细胞的特征,包括细胞周期永久停滞、分泌衰老相关分泌表型(SASP)以及铁过载等。这些特征为鉴别衰老小胶质细胞提供了重要依据。</p><p class="ql-align-justify">3.&nbsp;提出了靶向小胶质细胞衰老的潜在治疗策略,包括使用铁螯合剂和抗衰老药物等。这为治疗老年性神经退行性疾病提供了新的思路和可能性。</p><p class="ql-align-justify">4.&nbsp;将小胶质细胞衰老与神经退行性疾病的发病机制紧密联系起来,为深入理解这些疾病的病理生理过程提供了新视角。</p><p><strong style="color:rgb( 80 , 159 , 233 )">专家点评</strong></p><p class="ql-align-justify">这篇综述文章全面系统地阐述了小胶质细胞衰老在神经退行性疾病发病机制中的关键作用,为进一步深入探索这一领域提供了重要的理论基础。</p><p class="ql-align-justify">首先,文章详细概述了微小胶质细胞的特点及其在神经系统中的重要功能,为后续讨论奠定了基础。其次,文章重点介绍了衰老小胶质细胞的主要特征,如细胞周期永久停滞、SASP分泌和铁过载等,这些特征为鉴别和研究衰老小胶质细胞提供了关键依据。</p><p class="ql-align-justify">值得肯定的是,文章深入分析了衰老小胶质细胞在多种神经退行性疾病中的作用,如阿尔兹海默病、帕金森病、亨廷顿病和肌萎缩性侧索硬化等。研究发现,这些疾病中都观察到衰老小胶质细胞的明显增加,并可能参与了疾病的发病机制。这为我们理解神经退行性疾病的复杂病理过程提供了新的视角。</p><p class="ql-align-justify">此外,文章还提出了靶向小胶质细胞衰老的潜在治疗策略,包括利用铁螯合剂和抗衰老药物等。这为治疗这些疾病提供了新的思路和可能性。未来,进一步深入探讨这些治疗手段的具体作用机制和疗效,对于指导临床应用具有重要意义。</p><p class="ql-align-justify">总的来说,这篇综述文章在神经退行性疾病发病机制研究和潜在治疗策略探讨方面,提供了系统、全面的分析和见解。这对于推动该领域的研究进展具有重要的理论和实践价值。未来,我们需要进一步加强对衰老小胶质细胞的深入研究,探索其他潜在的调控机制和治疗靶点,为治疗这些难治性疾病提供新的突破口。</p><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545049920" src="https://img1p.dxycdn.com/p/s115/2024/1023/155/6794927213753109481.png?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=ltOfAaTHx8540667%2F9dyQaJ4ppo%3D" data-h="294" data-w="700" data-type="10" referrerpolicy="no-referrer"></div></div><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545050012" src="https://img1p.dxycdn.com/p/s115/2024/1023/303/2152707035463109481.png?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=1pt4sXmCk62hubk7SCLex%2BmHpMc%3D" data-h="332" data-w="674" data-type="10" referrerpolicy="no-referrer"></div></div><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545050138" src="https://img1p.dxycdn.com/p/s115/2024/1023/819/0428394024173109481.png?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=S6gDRJyB2KpnkwUrgV6uM8BVjRQ%3D" data-h="753" data-w="680" data-type="10" referrerpolicy="no-referrer"></div></div><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545050239" src="https://img1p.dxycdn.com/p/s115/2024/1023/620/0086991044973109481.png?Expires=1729810912&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=GZUn5gveSTLjxYBQLLb%2BaLQq8eo%3D" data-h="463" data-w="682" data-type="10" referrerpolicy="no-referrer"></div></div></description>
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<pubDate>Wed, 23 Oct 2024 09:03:54 GMT</pubDate>
<author>小威师姐</author>
<category>神经变性性疾病</category>
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<item>
<title>脑膜瘤是否为静脉溶栓禁忌症?</title>
<description><p>门诊一病人,发病时间窗内,既往有脑膜瘤病史,3次手术治疗,最近一次手术为4年前,有脑积水引流管置入治疗史,是否为静脉溶栓禁忌症呢?</p></description>
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<pubDate>Wed, 23 Oct 2024 08:50:51 GMT</pubDate>
<author>仅仅是一名小医生</author>
<category>脑膜瘤</category>
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<title>大负荷血栓取栓</title>
<description><p><br></p><div class="ql-image"><img data-file-center-id="545859611" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1025/525/0407464933995759481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=8Y9YmA4L%2B%2BBCSWoDoMY35OizixU%3D" data-h="4096" data-w="3072" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545859614" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1025/212/0445089596995759481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=aTivzAaJY9woENGGXeqaGqyB6sY%3D" data-h="4096" data-w="3072" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545859637" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1025/527/4471388269006759481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=TA6rAHy%2Fu4iJYoeqZD5T8kApYC8%3D" data-h="4096" data-w="3072" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545859621" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1025/681/8277189932006759481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=fvqmlNusCKuJwd%2FjgWcSFLg7bfw%3D" data-h="4096" data-w="3072" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545859632" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1025/552/8841768496006759481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=K5f0SiWQHYTo3dqCK179%2BY7wbKg%3D" data-h="4096" data-w="3072" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545859608" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1025/445/2952479203995759481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=vohXBwDD4W3d1iQzXUy57zI0SvE%3D" data-h="4096" data-w="3072" data-type="10" referrerpolicy="no-referrer"></div></description>
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<pubDate>Thu, 24 Oct 2024 22:18:14 GMT</pubDate>
<author>神内菜菜</author>
<category>神经内外</category>
<category>血栓</category>
</item>
<item>
<title>82岁女性,短期内两次急性脑梗死</title>
<description><p>患者肢体无力1周,言语不清6小时入院,</p><div class="ql-image"><img data-file-center-id="545738356" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/944/0652042895646649481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=amcQeXk2aU3xScudrWrCCafwfBU%3D" data-h="1332" data-w="3735" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><p>既往患2型糖尿病30年,长期使用甘精胰岛素控制血糖,血糖控制平稳,高血压2级30年,既往口服珍菊降压片,血压平稳,自行停药2年</p><p>急查头核磁如下</p><div class="ql-image"><img data-file-center-id="545736906" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/081/4437398164745649481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=FkOMwl5mSxOCsyq15y0UjmsiBBY%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545736900" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/173/0483637057645649481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=aCuqB9XpQYxW5ltyByBXbJbmbZQ%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545736919" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/483/4895434513845649481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=pIz28cPvA7Oj1JreIzYKykYNdEg%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545736909" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/061/4819453658745649481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=ZBAbGzyIgovXFWdMZ61hittEitE%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545736994" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/939/6330192557555649481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=uC%2Baw9%2BaXuUSAaPrNLsaGPoSiJg%3D" data-h="1311" data-w="4000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><p>保守治疗,疏血通注射液联合低分子肝素,阿托伐他汀钙,替格瑞洛,中医中药,针灸物理康复治疗20余天后患者可简单对答肢体无力症状改善。回家休养期间长期口服抗血小板聚集,稳定斑块治疗。间隔62天再次出现右侧肢体无力,间断抽搐、持续高热38.0-39.5℃,浅昏迷状态,再次完善头核磁如下</p><div class="ql-image"><img data-file-center-id="545735514" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/606/8887361486354649481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=oN2WS554QlcDm2GHgIpo7ycxeP8%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545735169" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/544/8670297513524649481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=t60A7%2B4oNXLz9nUnB%2BwD8nHadL8%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545735165" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/055/4642249598424649481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=0D%2BMYSuLOeK5u6tmB0hIcNgfsCg%3D" data-h="4000" data-w="3000" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545735140" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/175/2599075553324649481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=YaPEI6R4IHOPgo75P0YCzoDDyzE%3D" data-h="1309" data-w="3342" data-type="10" referrerpolicy="no-referrer"></div></description>
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<pubDate>Thu, 24 Oct 2024 15:02:39 GMT</pubDate>
<author>明天的太阳0568</author>
<category>神经内外</category>
<category>脑梗死</category>
<category>肢体无力</category>
<category>言语含糊不清</category>
</item>
<item>
<title>分享一例迷走右锁骨下动脉</title>
<description><p class="ql-itemtitle" data-type="caseInfo">病例信息</p><p><br></p><div><div class="ql-image"><img data-resize-w="100%" class="img-full-width" data-file-center-id="542801676" src="https://img1p.dxycdn.com/p/s115/2024/1019/831/4817938334675447481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=N0kOnt9oIeI9vMJHkMuoEF5UA6k%3D" data-h="4096" data-w="2304" data-type="10" referrerpolicy="no-referrer"></div></div><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545703091" src="https://img1p.dxycdn.com/p/s115/2024/1024/508/8250328786646449481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=8USl9DBrKFzDeQaBiZcREeRPth4%3D" data-h="3612" data-w="2304" data-type="10" referrerpolicy="no-referrer"></div></div><p class="ql-itemtitle" data-type="discussion">总结与讨论</p><p>迷走右侧锁骨下动脉相对罕见,是临床最常见的主动脉弓畸形,表现为右锁骨下动脉的起源和行程异常,由胚胎时期血管发育的异常所致,主动脉弓血管结构从后至前依次为迷走右锁骨下动脉、左锁骨下动脉及左、右颈总动脉。</p><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545707414" src="https://img1p.dxycdn.com/p/s115/2024/1024/833/6186226101918449481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=0dO0%2FBPTnqBHJPCTqVkA5qCTtkU%3D" data-h="500" data-w="929" data-type="10" referrerpolicy="no-referrer"></div></div><p>大多数无明显临床症状,一般都是在食道钡餐造影、胸部 CT 或者头颈部 CTA 中偶然发现</p></description>
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<pubDate>Thu, 24 Oct 2024 13:52:04 GMT</pubDate>
<author>医生胖子张</author>
<category>神经内外</category>
<category>迷走右锁骨下动脉</category>
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<item>
<title>出血性脑梗死指南</title>
<description><p>出血性脑梗死指南</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51080477</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51080477</guid>
<pubDate>Thu, 24 Oct 2024 13:19:55 GMT</pubDate>
<author>Sunshine慧宝贝</author>
<category>神经内外</category>
<category>出血性脑梗死</category>
</item>
<item>
<title>病例分享|61岁女患,意识障碍,结合影像学应该如何诊断?</title>
<description><p>女,63岁。</p><p>主诉:头痛3个月,发热伴意识障碍1周。</p><p>现病史:患者入院前3个月无明显诱因出现头痛,为后枕部胀痛,持续性,伴反应迟钝,记忆力下降。曾就诊于当地医院,完善脑电图见广泛中-重度异常脑电图,考虑自身免疫性脑炎,给予激素冲击,抗病毒等对症治疗后患者头痛症状稍有好转。患者于入院前1周出现意识不清并伴有发热。</p><p>既往史:高血压、糖尿病、乙肝、肺癌切除史(长期服用靶向药物)。</p><p>实验室检查:外院腰椎穿刺,颅内压60mmHg。脑脊液常规:潘氏试验阳性,脑脊液生化:葡萄糖 4.65mmol/L,蛋白1.20g/L,氯 117.5mmol/L。</p><p>入院后完善头部磁共振部分序列如下:</p><div class="ql-image"><img data-file-center-id="545653394" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/019/2194160699796149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=WK4%2B0w5t70XUjLHLbr8eOr9mo%2B0%3D" data-h="788" data-w="788" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653398" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/075/6522576000896149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=%2F%2BKsMfWDDpssoZSKkvmfP4qGDm4%3D" data-h="801" data-w="801" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653397" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/852/3346851899796149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=Dm5saiQoZ6dGFximRCEkeunO6Ek%3D" data-h="774" data-w="774" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653399" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/785/2346851899796149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=bg1%2FJHhV%2FiYsCFBF%2BlJB7NSv39k%3D" data-h="792" data-w="792" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653401" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/235/0405799899796149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=N1RDAj8XZAZCaXqD08NLE%2BJcWc0%3D" data-h="783" data-w="783" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653396" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/845/4346851899796149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=ViTCauAGkmZibk9isa%2FGu1inVhg%3D" data-h="738" data-w="738" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653395" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/043/4832116300896149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=2CGTzCdqbP9FogfjFdOQfW0wN%2BM%3D" data-h="723" data-w="723" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653491" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/624/8868186730507149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=WKUgC5TpYxbAu4mM56xmXkG4MpM%3D" data-h="711" data-w="711" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653500" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/841/2348908130507149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=%2BwSrOvfNyTePgNdnKp8x13QF97g%3D" data-h="720" data-w="720" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653495" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/392/6733909640507149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=u%2FFosgTWJjWy7RjOcOBKOvteJl0%3D" data-h="702" data-w="702" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653494" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/465/8020977930507149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=cxjPqUF7wEkTlYw7IVEZPaw1et4%3D" data-h="673" data-w="673" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653493" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/631/4834070920507149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=LjDndfAlqIzzK%2FPf1Sg%2FpKnDKls%3D" data-h="673" data-w="673" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653496" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/157/0867823740507149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=nsL0veCDYii87fxZBhNXiH12unw%3D" data-h="665" data-w="665" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653492" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/102/2992909920507149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=E8Dkmv8YYSywj4cTQwCGJ2t%2Fplk%3D" data-h="732" data-w="732" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653499" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/474/0658355620507149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=hTHSGR5Ihu7x6jdaXITy7QT2yJA%3D" data-h="696" data-w="696" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653555" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/619/4602769581017149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=vwh1cS5E1nSvQnpuinBAX60vuaI%3D" data-h="694" data-w="694" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653558" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/204/0677745581017149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=Mnsk%2BEIFvObj4V6PxLePEc3tYr8%3D" data-h="690" data-w="690" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653559" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/974/8805812561017149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=hXlB1YUpYNJhfM1AdKlIHMLB9t0%3D" data-h="699" data-w="699" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653553" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/587/0259375861017149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=veA%2BG3KQMgyTeK25c5BFr0%2BE2TE%3D" data-h="676" data-w="676" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653557" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/842/3300621271017149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=TRjvh%2BFfvaFby7Acf%2FQVvceDaW0%3D" data-h="689" data-w="689" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653554" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/934/2300621271017149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=CRih3%2F7gQqiaxpFF9gmvlhpSq9U%3D" data-h="671" data-w="671" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653552" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/907/0401176071017149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=yQy%2BQy3InJb%2BVFBHk7Q2ipdEHcU%3D" data-h="666" data-w="666" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653556" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/812/6737139481017149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=R0c3Hkshn3JSYrX2s1vY%2BNiw6zc%3D" data-h="666" data-w="666" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653618" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/579/2302391223417149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=wGU1JFBngedfgRzxJLPfaSSDV34%3D" data-h="692" data-w="692" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653610" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/888/0460230323417149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=hMxl1PtKpwWczXsJnA8sNGaonNY%3D" data-h="681" data-w="681" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653611" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/969/4494154323417149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=taBIGAq9DZ8NEuCixkMqVJVwW%2BE%3D" data-h="653" data-w="653" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653614" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/457/2118983223417149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=fBuO87HPYUuDBk9Ti1gtzrgS7DQ%3D" data-h="645" data-w="645" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653613" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/111/6142100133417149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=vIdMcsq%2FXQXAE%2FNTOSfmILy3XWM%3D" data-h="658" data-w="658" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653615" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/137/0276822323417149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=PiuJiDfqcpEKhna5abzB%2FdnYF7A%3D" data-h="631" data-w="631" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653616" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/329/3302391223417149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=iVDjoJu%2BLnkq%2B1SR4vazHDnoIsI%3D" data-h="650" data-w="650" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653617" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/617/6142908223417149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=hMzgRiXQZElcC6MjjrOgd5iJ1I0%3D" data-h="618" data-w="618" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653663" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/497/0829868535717149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=%2BdHDlovFEbnX%2FL3TtqB%2FIbiSCpY%3D" data-h="589" data-w="589" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653664" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/483/4669484635717149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=oy8TBQGiUjBMPSMNTJ2AabIvEsc%3D" data-h="602" data-w="602" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653670" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/394/8803976755717149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=KzgH8BvTkJ3S63jfF%2FkfilesusA%3D" data-h="716" data-w="716" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653667" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/835/3365270575717149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=nSdYW%2BQ981zBBWauFgrgszSNT8Y%3D" data-h="667" data-w="667" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653666" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/319/2365270575717149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=%2BxYNO5lWHx7mfJGfnPFzjDUuYmQ%3D" data-h="712" data-w="712" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653665" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/365/4458033675717149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=%2BwdnQ0%2Bd9uIiIfjmO9KI8xBuIkQ%3D" data-h="738" data-w="738" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545653668" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/563/2952070975717149481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=gPqLqcPW%2F78lfJWQcPyqCKbj8Ko%3D" data-h="820" data-w="820" data-type="10" referrerpolicy="no-referrer"></div><p>请结合影像学及患者病史,分析患者诊断思路。期待评论区各位老师高见~</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51080115</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51080115</guid>
<pubDate>Thu, 24 Oct 2024 11:47:36 GMT</pubDate>
<author>青鹊词</author>
<category>神经内外</category>
<category>头痛</category>
<category>意识模糊</category>
<category>发热</category>
</item>
<item>
<title>这种脑梗倾向溶栓吗</title>
<description><p><br></p><div class="ql-image"><img data-file-center-id="545628887" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/193/0067757044562049481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=KQb334nDE5xHhTeoCR%2BDzrjQw3E%3D" data-h="4284" data-w="5712" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545631135" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/605/0631994507693049481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=uXu%2FEXIWFukz4W6Y7HgpAG4lzMA%3D" data-h="3928" data-w="3744" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><p>一个有图1上这么多病的75岁男病人,2月前冠脉搭桥,因双眼凝视、失语及右侧肢体、左下肢肌力1级2小时入院,发病前生活可自理。这种病人倾向于溶栓吗</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51079985</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51079985</guid>
<pubDate>Thu, 24 Oct 2024 10:51:15 GMT</pubDate>
<author>晒太阳的韭菜</author>
<category>神经内外</category>
<category>脑梗死</category>
</item>
<item>
<title>星期二门诊见闻(314):出个小试题:这张片子能发现哪些异常?</title>
<description><p class="ql-itemtitle" data-type="caseInfo">病例信息</p><p><br></p><div class="ql-image"><img data-file-center-id="545610731" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/594/0253233919922939481.jpg?Expires=1729814456&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=yeeqXLbrSwe%2FUszNWKjtNgUEpjM%3D" data-h="790" data-w="3058" data-type="10" referrerpolicy="no-referrer"></div><p><strong>小试题:提示哪些异常?</strong></p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51079841</link>
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<pubDate>Thu, 24 Oct 2024 10:08:51 GMT</pubDate>
<author>FangQU</author>
<category>神经内外</category>
</item>
<item>
<title>阿尔茨海默病:从基础到临床2021.10版</title>
<description><p>阿尔茨海默病:从基础到临床2021.10版</p></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51079363</link>
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<pubDate>Thu, 24 Oct 2024 08:15:58 GMT</pubDate>
<author>医学书屋</author>
<category>神经内外</category>
<category>阿尔茨海默症</category>
</item>
<item>
<title>中国偏头痛急性期治疗指南(第一版)</title>
<description><p>近年来,偏头痛的治疗策略不断规范更新,然而国内在偏头痛急性期治疗实践中仍面临一系列挑战,包括药物选择不当、治疗不足或使用过度、安全性与耐受性不佳等,以及对特定人群、特殊类型偏头痛急性期治疗规范仍相对匮乏。为此,由中国医师协会神经内科医师分会、中国研究型医院学会头痛与感觉障碍专业委员会共同组织编写制订本指南,对《中国偏头痛诊治指南(2022 版)》中的急性期治疗进行补充与更新,针对偏头痛药物和非药物治疗、偏头痛持续状态及特殊人群的急性期管理策略进行详细阐述,旨在进一步提升偏头痛急性期治疗效率。</p></description>
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<pubDate>Thu, 24 Oct 2024 08:01:10 GMT</pubDate>
<author>兰亭序1990</author>
<category>神经内外</category>
<category>偏头痛</category>
</item>
<item>
<title>中国偏头痛急性期治疗指南</title>
<description><p>中国偏头痛急性期治疗指南(第一版)</p><p>近年来,偏头痛的治疗策略不断规范更新,然而国内在偏头痛急性期治疗实践中仍面临一系 列挑战,包括药物选择不当、治疗不足或使用过度、安全性与耐受性不佳等,以及对特定人群、特殊 类型偏头痛急性期治疗规范仍相对匮乏。为此,由中国医师协会神经内科医师分会、中国研究型医院 学会头痛与感觉障碍专业委员会共同组织编写制订本指南,对《中国偏头痛诊治指南(2022 版)》中 的急性期治疗进行补充与更新,针对偏头痛药物和非药物治疗、偏头痛持续状态及特殊人群的急性期 管理策略进行详细阐述,旨在进一步提升偏头痛急性期治疗效率。</p></description>
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<pubDate>Thu, 24 Oct 2024 07:49:07 GMT</pubDate>
<author>borisdoctor1971</author>
<category>神经内外</category>
<category>偏头痛</category>
</item>
<item>
<title>中国偏头痛急性期治疗指南(第一版)_中国医师协会神经内科医师分会_</title>
<description><p>中国偏头痛急性期治疗指南(第一版)_中国医师协会神经内科医师分会_</p></description>
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<pubDate>Thu, 24 Oct 2024 06:03:43 GMT</pubDate>
<author>yzb4062073</author>
<category>神经内外</category>
<category>偏头痛</category>
</item>
<item>
<title>面神经炎使用激素的求助</title>
<description><p>菜鸟新人医生求问,今天新收了一个面神经炎的病人,但是既往是有急性淋巴细胞性白血病的,长期使用长春新碱化疗治疗,这种情况可使用10mg地塞米松抗炎治疗嘛?<img class="ql-expression" src="https://assets.dxycdn.com/app/bbs/emotions/dxmm/01.png" referrerpolicy="no-referrer"></p></description>
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<pubDate>Thu, 24 Oct 2024 05:08:26 GMT</pubDate>
<author>聚窟洲振刀怪</author>
<category>神经内外</category>
<category>面神经麻痹</category>
</item>
<item>
<title>左下肢麻木就这么简单吗?</title>
<description><p>患者女性,63 岁,主因“双下肢麻木 3 月余,伴双下肢无力 2 月余”于 2024年 05 月 24 日入院。</p><p>现病史:患者缘于 3 月前出现左下肢麻木,就诊于当地医院,考虑为“脑血管病”并给予抗血小板、调脂固斑、改善循环等治疗,症状未见好转,并逐渐出现右下肢麻木,无明显肢体疼痛,无踩棉花感,无二便障碍,无间断性跛行。2 个月前患者出现双下肢无力,行走缓慢,但尚可独立行走,就诊于当地医院,查肌电图示多发周围神经损害(无具体结果),诊断为“糖尿病周围神经病”,未给予特殊治疗,后患者下肢无力进行性加重,逐渐进展至需借助支具行走,为求进一步诊治就诊于我院,并收入院治疗。患者自发病以来精神、饮食尚可,二便正常,无发热,否认前驱感染史,体重无减轻。</p><p>既往史:2008 年 1 月因“腹痛”就诊于我院,诊断为急性胰腺炎,行剖腹探查术及腹腔引流术,术后恢复顺利;2008 年 7 月因“腰痛伴右下肢疼痛憋胀”就诊于外院,行腰椎 MR 示腰椎 4-5 椎体异常信号,考虑炎性改变,腰椎 CT 考虑腰 4-5 椎体结核,腰 4-5 椎间盘突出,行腹膜外腰 4-5 椎间隙探查术,椎间盘及骨质活检考虑“(腰 4-5)急、慢性炎症”,诊断为“腰 4-5 椎间盘炎”,术 后卧床休养;2008 年 9 月因“持续性头痛 1 月”入住我院,头颅 MRI 示:右侧顶枕叶和左侧颞叶可见长 T1,长 T2 信号,MRV 未见异常,行腰穿脑脊液压力 140mmH2O,CSF 常规正常,CSF 生化 Pro 0.6g/L,细胞学仅见 4 个淋巴细胞,脑脊液囊虫试验(+),住院试用吡喹酮出现头部剧痛,考虑脑囊虫可能,期间家属曾于北京询专家会诊,考虑不能除外脑膜癌,后因故自动出院;2018 年 10 月于外院行脑组织活检,病理回报考虑炎性病变(具体不详),家属诉住院治疗后(药物不详)出现病情加重、昏迷,自动出院休养后自愈,未规律服用特殊药物;甲状腺功能减退病史 10 年,平素口服“优甲乐”治疗,控制不佳,未规律复查;糖尿病病史 5 年,平素口服“阿卡波糖、二甲双胍格列本脲”,未规律监测;高血压病史5 年,最高血压不详,平素口服“苯磺酸左氨氯地平、酒石酸美托洛尔”控制,未规律监测;高脂血症 5 年,平素口服“非诺贝特”。否认肝炎、结核等传染病病史,否认食物、药物过敏史。</p><p>个人史及家族史:生于原籍,久居当地,未到过疫区、牧区,无烟酒嗜好,否认毒物及有害物质接触史,否认性病、冶游史。适龄结婚,配偶及孩子体健。</p><p>月经史:初潮&nbsp;14 岁,月经周期 4-5/26-28,52 岁绝经。</p><p>一般体格检查:T 36.5℃ P 55 次/分 R 17 次/分 BP 150/92mmHg,发育正常,营</p><p>养中等,双肺呼吸音清,未闻及干湿性啰音,心率 55 次/分,律齐,未闻及杂音,</p><p>腹软,无压痛及肌紧张,双下肢无指凹性水肿。</p><p>神经系统查体:神清,高级皮层功能正常,语利,双瞳孔正大等圆,直径 3.0mm,</p><p>眼球各方向运动自如,无眼震。双侧额纹对称,无鼻唇沟变浅,伸舌不偏。双上</p><p>肢近端肌力 4-级,远端肌力 4+级,双下肢肌力 4-级,四肢肌张力正常。双上肢</p><p>腱反射未引出,双下肢腱反射(++),双侧巴氏征(+)。感觉系统查体:C4 平面</p><p>以下针刺觉、振动觉减退。共济运动查体欠配合。颈抵抗(-)。</p><p>入院后辅助检查:血常规:WBC 8.60*109/L,NE% 75.04%,Hb 103g/L(115-150),MCV 101.2fl(82-100),PLT 213*109/L;余尿便常规大致正常。生化全项:Urea 9.90mmol/L(3.1-8.8),Cr 162.0μmol/L(41-81),β2 MG:5.10mg/L(1.3-3.0),TG:2.45mmol/L(0.56-1.7),LDL-C 1.17mmol/L(2.07-3.37),GLU8.78mmol/L,Hcy:23.43μmol/L;余肝功能、电解质未见异常。凝血功能:D-Dimer 0.26μg/ml(0-0.243)。代谢+免疫:s-TSH 23.771mIU/L(0.55-4.78),FT3:2.71pmol/L(3.5-6.5),An-TPOAb:>1300IU/ml(<60),An-TGAb:203.40IU/ml(<4.5)。HbA1C:8.4%。自身抗体:ANA(+)胞浆型+颗粒 1:100,VitD:42.10nmol/L(>50),余抗中性粒细胞胞浆抗体、抗磷脂抗体、CRP、血沉、甲状旁腺激素、免疫球蛋白、风湿四项、曲霉菌免疫学实验、术前四项未见明显异常。颅脑 CT:1.考虑右侧颞顶枕叶软化灶伴少许出血;2.脑萎缩。胸部 CT:1.两肺多发结节;2.两肺下叶条片影,考虑炎性或少许肺组织膨胀不良;3.两侧胸膜局部增厚;4.肺动脉主干增宽;5.主动脉及冠状动脉硬化。腹部 CT:1.胰头部饱满,体尾部显示欠清;2.肝脏稍增大;3.胆囊结石;4.上腹前部中线区腹壁薄弱,局部脂肪疝入腹壁;5.左肾稍小,左肾后缘低密度影,直径约 0.8cm,CT 值约 0-40HU;6.腰 4-5 椎体骨性融合。颅脑 MR 平扫+SWI:1.右侧颞枕叶多发异常信号 2.余幕上脑质多发异常信号,部分为腔隙性梗死灶,部分为非特异性脑白质病变,符合 FSⅠ级改变;3.老年脑改变。颅脑 MR 增强:1.符合右顶部术后改变,请结合病史;2.右侧颞顶枕叶多发环形强化结节伴脑膜强化,考虑慢性炎性肉芽肿病变。颈髓 MR 平扫:1.颈 2-7 椎体水平脊髓异常信号,性质待定;2.颈椎生理曲度变直,轻度骨质增生,颈椎间盘变性;3.颈 3-4 椎间盘水平黄韧带增厚。颈髓 DWI:颈髓增粗,可见散在点片状&nbsp;DWI 高信号,ADC 范围较大,呈高信号。
颈髓 MR 增强:1.颈 2-7 椎体水平髓内及脊膜异常强化,结合颅脑检查,考虑炎
性改变;2.颈椎轻度骨质增生,生理曲度变直。
胸髓 MR 平扫:1.胸髓 MR 平扫未见明显异常;2.胸椎骨质增生。
腰椎穿刺:脑脊液压力 120mmH2O
CSF 常规:总细胞 1018*10
6
/L,白细胞 17*10
6
/L(穿刺伤)。
</p><p>CSF 生化:PRO 1.16g/L(0.15-0.45)。
</p><p>血清 AQP4 抗体:阳性(+)1:100。
</p><p>脑脊液 AQP4 抗体:阳性(+)1:100;
</p><p>脑脊液抗 GFAP 抗体:阳性(+)1:32。
</p><p>血清+脑脊液寡克隆区带:Ⅳ型,无鞘内合成,存在外周 B 细胞免疫反应,且伴
有血脑屏障破坏;脑脊液 IgG 指数升高;IgG 24h 鞘内合成率升高。
PDD 试验:阴性。
为明确诊断,于 2024-06-05 行右侧枕叶病灶切除术及组织活检</p><div class="ql-image"><img data-file-center-id="545409656" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/081/4287932552885929481.jpg?Expires=1729814457&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=MU8jhz5xMjARbzMv7hlxyfi50l0%3D" data-h="791" data-w="1080" data-type="10" referrerpolicy="no-referrer"></div><p><br></p><div class="ql-image"><img data-file-center-id="545409657" class="img-full-width" src="https://img1p.dxycdn.com/p/s115/2024/1024/054/6313210642885929481.jpg?Expires=1729814457&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=QAJU2cG8YY8YaH%2BxXgXmieEs6A0%3D" data-h="791" data-w="1080" data-type="10" referrerpolicy="no-referrer"></div><p>请各位分析:</p></description>
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<pubDate>Thu, 24 Oct 2024 03:44:59 GMT</pubDate>
<author>理性人</author>
<category>神经内外</category>
<category>糖尿病性周围神经病</category>
<category>下肢麻木</category>
<category>双下肢无力</category>
</item>
<item>
<title>烟雾血管病外科手术学</title>
<description><p>本书共分十二章,主要内容包括:初步认识烟雾血管病、烟雾血管病的流行病学、烟雾血管病的组织及病理学、脑血管的新生与增生、烟雾血管病的发病机制、烟雾血管病的影像诊断、烟雾血管病与认知功能障碍、烟雾血管病的联合手术等。</p></description>
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<pubDate>Thu, 24 Oct 2024 01:07:13 GMT</pubDate>
<author>bsqyy</author>
<category>神经内外</category>
</item>
<item>
<title>202401 专家建议:局部止血剂在神经脊柱手术中的各种出血部位和情况下的应用</title>
<description><p>202401 专家建议:局部止血剂在神经脊柱手术中的各种出血部位和情况下的应用</p></description>
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<pubDate>Wed, 23 Oct 2024 23:08:53 GMT</pubDate>
<author>哆啦医梦</author>
<category>神经内外</category>
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<item>
<title>脑梗死与肌红蛋白</title>
<description><p>求助为什么脑梗死病人普遍肌红蛋白都高两者有什么关系吗</p></description>
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<pubDate>Wed, 23 Oct 2024 17:08:07 GMT</pubDate>
<author>dxy_4amu3ov2</author>
<category>神经内外</category>
<category>脑梗死</category>
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<item>
<title>阿替普酶这么贵,20mg的一只就要1700,报销多吗?</title>
<description><p>一个人不得用个3支</p></description>
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<pubDate>Wed, 23 Oct 2024 14:20:40 GMT</pubDate>
<author>小壮兵爱学习</author>
<category>神经内外</category>
</item>
<item>
<title>病因讨论</title>
<description><p class="ql-itemtitle" data-type="caseInfo">病例信息</p><p><strong>【患者信息】</strong>:男38岁</p><p><strong>【主诉】</strong>:左侧肢体间断麻木1个月。</p><p><strong>【现病史及既往史】</strong>:该患者一个月以来左侧肢体间断麻木,以小拇指、食指和脚底为著,伴有左小腿僵硬。既往高血压病史1年,血压最高152/95mmHg。无糖尿病病史。一个前发现谷丙转氨酶升高156。脂肪肝病史6年。</p><p><strong>【检查】</strong>:头部磁共振:右侧M1和A1起始部狭窄。颈椎磁共振:颈5.6椎间盘突出。</p><p><strong>【临床诊断】</strong>:脑动脉狭窄、颈椎间盘突出</p><p><strong>【治疗经过及结果】</strong>:</p></description>
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<pubDate>Wed, 23 Oct 2024 09:52:34 GMT</pubDate>
<author>dxy_ncyxiju2</author>
<category>神经内外</category>
<category>颈椎间盘突出症</category>
<category>动脉狭窄</category>
<category>肢体或躯干麻木</category>
<category>肢体僵硬感</category>
</item>
<item>
<title>Neuroprotection|神经退行性疾病中的小胶质细胞衰老:见解、影响和治疗机会</title>
<description><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545049566" src="https://img1p.dxycdn.com/p/s115/2024/1023/185/4686996926733109481.png?Expires=1729814457&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=87APaMDfQHG%2FInPTdkqyWEMjArI%3D" data-h="242" data-w="621" data-type="10" referrerpolicy="no-referrer"></div></div><p class="ql-align-center" style="text-align:center"><strong style="color:rgb( 247 , 100 , 100 )"><a class="ql-link" href="https://onlinelibrary.wiley.com/doi/10.1002/nep3.56?msockid=28c2e734863762150015f364877463f4" target="_blank" rel="noopener noreferrer">点击此处</a>即可免费获取论文原文</strong></p><p>本文系统地探讨了小胶质细胞衰老在神经退行性疾病中的作用。首先,文章概述了小胶质细胞的特点,包括其源于卵黄囊、在神经系统中的多种功能等。其次,文章详细介绍了小胶质细胞衰老的特征,如细胞周期永久停滞、分泌senescence相关分泌表型(SASP)以及铁过载等,这些特点可作为其衰老表型的标志。其次,文章重点探讨了小胶质细胞衰老在多种神经退行性疾病中的作用,如阿尔兹海默病、帕金森病、亨廷顿病和肌萎缩性侧索硬化。研究发现,这些疾病中都观察到衰老小胶质细胞的增加,并可能参与了疾病的发生发展。最后,文章提出了靶向小胶质细胞衰老的潜在治疗策略,包括利用铁螯合剂和抗衰老药物等,这为治疗老年性神经退行性疾病提供了新的思路。总的来说,本文系统阐述了小胶质细胞衰老在神经退行性疾病中的重要作用,为深入探索这一领域提供了重要的理论基础。</p><p><strong style="color:rgb( 80 , 159 , 233 )">亮点</strong></p><p class="ql-align-justify">1.&nbsp;深入探讨了小胶质细胞衰老在神经退行性疾病发病机制中的作用。现有研究表明,衰老小胶质细胞在阿尔兹海默病、帕金森病、亨廷顿病和肌萎缩性侧索硬化等疾病中均有增加,这可能是这些疾病发生发展的重要因素。</p><p class="ql-align-justify">2.&nbsp;系统总结了衰老小胶质细胞的特征,包括细胞周期永久停滞、分泌衰老相关分泌表型(SASP)以及铁过载等。这些特征为鉴别衰老小胶质细胞提供了重要依据。</p><p class="ql-align-justify">3.&nbsp;提出了靶向小胶质细胞衰老的潜在治疗策略,包括使用铁螯合剂和抗衰老药物等。这为治疗老年性神经退行性疾病提供了新的思路和可能性。</p><p class="ql-align-justify">4.&nbsp;将小胶质细胞衰老与神经退行性疾病的发病机制紧密联系起来,为深入理解这些疾病的病理生理过程提供了新视角。</p><p><strong style="color:rgb( 80 , 159 , 233 )">专家点评</strong></p><p class="ql-align-justify">这篇综述文章全面系统地阐述了小胶质细胞衰老在神经退行性疾病发病机制中的关键作用,为进一步深入探索这一领域提供了重要的理论基础。</p><p class="ql-align-justify">首先,文章详细概述了微小胶质细胞的特点及其在神经系统中的重要功能,为后续讨论奠定了基础。其次,文章重点介绍了衰老小胶质细胞的主要特征,如细胞周期永久停滞、SASP分泌和铁过载等,这些特征为鉴别和研究衰老小胶质细胞提供了关键依据。</p><p class="ql-align-justify">值得肯定的是,文章深入分析了衰老小胶质细胞在多种神经退行性疾病中的作用,如阿尔兹海默病、帕金森病、亨廷顿病和肌萎缩性侧索硬化等。研究发现,这些疾病中都观察到衰老小胶质细胞的明显增加,并可能参与了疾病的发病机制。这为我们理解神经退行性疾病的复杂病理过程提供了新的视角。</p><p class="ql-align-justify">此外,文章还提出了靶向小胶质细胞衰老的潜在治疗策略,包括利用铁螯合剂和抗衰老药物等。这为治疗这些疾病提供了新的思路和可能性。未来,进一步深入探讨这些治疗手段的具体作用机制和疗效,对于指导临床应用具有重要意义。</p><p class="ql-align-justify">总的来说,这篇综述文章在神经退行性疾病发病机制研究和潜在治疗策略探讨方面,提供了系统、全面的分析和见解。这对于推动该领域的研究进展具有重要的理论和实践价值。未来,我们需要进一步加强对衰老小胶质细胞的深入研究,探索其他潜在的调控机制和治疗靶点,为治疗这些难治性疾病提供新的突破口。</p><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545049920" src="https://img1p.dxycdn.com/p/s115/2024/1023/155/6794927213753109481.png?Expires=1729814457&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=zQuVqvakgePXeIIlL%2F1TMipJ%2BV8%3D" data-h="294" data-w="700" data-type="10" referrerpolicy="no-referrer"></div></div><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545050012" src="https://img1p.dxycdn.com/p/s115/2024/1023/303/2152707035463109481.png?Expires=1729814457&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=VTkuG%2FLw4PR783Q0RBe8HhM5B0k%3D" data-h="332" data-w="674" data-type="10" referrerpolicy="no-referrer"></div></div><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545050138" src="https://img1p.dxycdn.com/p/s115/2024/1023/819/0428394024173109481.png?Expires=1729814457&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=kVtjR4Koo4J%2FJZL5tmDGs1W%2B90Q%3D" data-h="753" data-w="680" data-type="10" referrerpolicy="no-referrer"></div></div><div><div class="ql-image"><img data-resize-w="undefined" data-file-center-id="545050239" src="https://img1p.dxycdn.com/p/s115/2024/1023/620/0086991044973109481.png?Expires=1729814457&amp;OSSAccessKeyId=LTAI5tSDK8MpKoGzn4zRvWFK&amp;Signature=6ZGb39LYvVagzMNXWvVdXOFK7cM%3D" data-h="463" data-w="682" data-type="10" referrerpolicy="no-referrer"></div></div></description>
<link>https://www.dxy.cn/bbs/newweb/pc/post/51075377</link>
<guid isPermaLink="false">https://www.dxy.cn/bbs/newweb/pc/post/51075377</guid>
<pubDate>Wed, 23 Oct 2024 09:03:54 GMT</pubDate>
<author>小威师姐</author>
<category>神经内外</category>
<category>神经变性性疾病</category>
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