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<!DOCTYPE html>
<html xmlns="http://www.w3.org/1999/xhtml" lang="en" xml:lang="en"><head>
<meta charset="utf-8">
<meta name="generator" content="quarto-1.3.353">
<meta name="viewport" content="width=device-width, initial-scale=1.0, user-scalable=yes">
<meta name="author" content="Mr Sougata Maity, Dr Santam Chakraborty">
<title>PROPARA RTTQA Round 1 and 2</title>
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<h2 id="toc-title">Table of contents</h2>
<ul>
<li><a href="#round-1" id="toc-round-1" class="nav-link active" data-scroll-target="#round-1">Round 1</a></li>
<li><a href="#introduction" id="toc-introduction" class="nav-link" data-scroll-target="#introduction">Introduction</a></li>
<li><a href="#results" id="toc-results" class="nav-link" data-scroll-target="#results">Results</a></li>
<li><a href="#round-2" id="toc-round-2" class="nav-link" data-scroll-target="#round-2">Round 2</a></li>
<li><a href="#introduction-1" id="toc-introduction-1" class="nav-link" data-scroll-target="#introduction-1">Introduction</a></li>
<li><a href="#results-1" id="toc-results-1" class="nav-link" data-scroll-target="#results-1">Results</a></li>
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<main class="content" id="quarto-document-content">
<header id="title-block-header" class="quarto-title-block default">
<div class="quarto-title">
<h1 class="title">PROPARA RTTQA Round 1 and 2</h1>
</div>
<div class="quarto-title-meta">
<div>
<div class="quarto-title-meta-heading">Author</div>
<div class="quarto-title-meta-contents">
<p>Mr Sougata Maity, Dr Santam Chakraborty </p>
</div>
</div>
</div>
</header>
<section id="round-1" class="level1">
<h1>Round 1</h1>
</section>
<section id="introduction" class="level1">
<h1>Introduction</h1>
<p>This is the first iteration of the quality assurance for PROPARA trial. Planning CT scans of two de-identified patients suffering from cervical cancer who gave consent for CHAVI bio banking was used for this. The objective was to determine the discrepancies in the target volume and organ at risk segmentation for the cases. Both cases were segmented by two institutes with a common structure template. The quantitative metrics of volume, dice similarity coefficient and center of mass shifts were obtained from the Contouring statistics module in Eclipse 15.5 workstation. Analysis was done in R.</p>
</section>
<section id="results" class="level1">
<h1>Results</h1>
<p>First we show all the structures that have been delineated by the institutes. Note that there was discrepancy in the labeling of inferior vena cava, vessels and spinal canal which had to be corrected. In addition when importing into Varian Eclipse TPS it was found the the structure names were altered as the labels were not setup appropriately. These had to be corrected manually in the TPS.</p>
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</style>
<table class="gt_table" data-quarto-disable-processing="false" data-quarto-bootstrap="false">
<thead>
<tr class="gt_col_headings">
<th class="gt_col_heading gt_columns_bottom_border gt_left" rowspan="1" colspan="1" scope="col" id="<strong>Characteristic</strong>"><strong>Characteristic</strong></th>
<th class="gt_col_heading gt_columns_bottom_border gt_center" rowspan="1" colspan="1" scope="col" id="<strong>KMC</strong>, N = 2<span class="gt_footnote_marks" style="white-space:nowrap;font-style:italic;font-weight:normal;"><sup>1</sup></span>"><strong>KMC</strong>, N = 2<span class="gt_footnote_marks" style="white-space:nowrap;font-style:italic;font-weight:normal;"><sup>1</sup></span></th>
<th class="gt_col_heading gt_columns_bottom_border gt_center" rowspan="1" colspan="1" scope="col" id="<strong>PGI</strong>, N = 2<span class="gt_footnote_marks" style="white-space:nowrap;font-style:italic;font-weight:normal;"><sup>1</sup></span>"><strong>PGI</strong>, N = 2<span class="gt_footnote_marks" style="white-space:nowrap;font-style:italic;font-weight:normal;"><sup>1</sup></span></th>
<th class="gt_col_heading gt_columns_bottom_border gt_center" rowspan="1" colspan="1" scope="col" id="<strong>TMC</strong>, N = 2<span class="gt_footnote_marks" style="white-space:nowrap;font-style:italic;font-weight:normal;"><sup>1</sup></span>"><strong>TMC</strong>, N = 2<span class="gt_footnote_marks" style="white-space:nowrap;font-style:italic;font-weight:normal;"><sup>1</sup></span></th>
</tr>
</thead>
<tbody class="gt_table_body">
<tr><td headers="label" class="gt_row gt_left">Anal_Canal</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Aorta</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Bladder</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Bone_Marrow</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">1 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">0 (NA%)</td>
<td headers="stat_3" class="gt_row gt_center">1 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left"> Unknown</td>
<td headers="stat_1" class="gt_row gt_center">1</td>
<td headers="stat_2" class="gt_row gt_center">2</td>
<td headers="stat_3" class="gt_row gt_center">1</td></tr>
<tr><td headers="label" class="gt_row gt_left">Bowel_Bag</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">CTVn_Paraaortic</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">CTVn_Pelvic</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">CTVp</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Duodenum</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Femur_L</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Femur_R</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">GTVn</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Kidney_L</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Kidney_R</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Liver</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Pancreas</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Rectum</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">SpinalCanal</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">1 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left"> Unknown</td>
<td headers="stat_1" class="gt_row gt_center">0</td>
<td headers="stat_2" class="gt_row gt_center">1</td>
<td headers="stat_3" class="gt_row gt_center">0</td></tr>
<tr><td headers="label" class="gt_row gt_left">V_CavaInferior</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Vessels</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left">Sigmoid_Colon</td>
<td headers="stat_1" class="gt_row gt_center"><br></td>
<td headers="stat_2" class="gt_row gt_center"><br></td>
<td headers="stat_3" class="gt_row gt_center"><br></td></tr>
<tr><td headers="label" class="gt_row gt_left"> Yes</td>
<td headers="stat_1" class="gt_row gt_center">1 (100%)</td>
<td headers="stat_2" class="gt_row gt_center">2 (100%)</td>
<td headers="stat_3" class="gt_row gt_center">2 (100%)</td></tr>
<tr><td headers="label" class="gt_row gt_left"> Unknown</td>
<td headers="stat_1" class="gt_row gt_center">1</td>
<td headers="stat_2" class="gt_row gt_center">0</td>
<td headers="stat_3" class="gt_row gt_center">0</td></tr>
</tbody>
<tfoot class="gt_footnotes">
<tr>
<td class="gt_footnote" colspan="4"><span class="gt_footnote_marks" style="white-space:nowrap;font-style:italic;font-weight:normal;"><sup>1</sup></span> n (%)</td>
</tr>
</tfoot>
</table>
</div>
</div>
</div>
<p>Now we will see the structure wise volumes at different centers.</p>
<div class="cell">
<div class="cell-output-display">
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#ejhtzpbmis .gt_stub {
color: #333333;
background-color: #FFFFFF;
font-size: 100%;
font-weight: initial;
text-transform: inherit;
border-right-style: solid;
border-right-width: 2px;
border-right-color: #D3D3D3;
padding-left: 5px;
padding-right: 5px;
}
#ejhtzpbmis .gt_stub_row_group {
color: #333333;
background-color: #FFFFFF;
font-size: 100%;
font-weight: initial;
text-transform: inherit;
border-right-style: solid;
border-right-width: 2px;
border-right-color: #D3D3D3;
padding-left: 5px;
padding-right: 5px;
vertical-align: top;
}
#ejhtzpbmis .gt_row_group_first td {
border-top-width: 2px;
}