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Refactor OmicsContainer and OmicsDataMap classes to allow multi-sample preprocessing #5

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vvvieira opened this issue May 15, 2020 · 1 comment
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enhancement New feature or request help wanted Extra attention is needed

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@vvvieira
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This paper describes a very straightforward framework for gene/reaction-level omics integration. The current wrappers are only good for generic pipelines where the sample is already preprocessed before calling reconstruction methods.

To this end, OmicsContainer and IntegrationStrategy classes should be changed to accommodate the following parameters described in the paper:

  • Thresholding at the gene vs reaction level
  • Threshold based on a global value vs local-values for each gene/reaction across multiple samples (e.g. median, quantiles)
  • Which functions replace AND/OR operators
@vvvieira vvvieira added enhancement New feature or request help wanted Extra attention is needed labels May 15, 2020
@vvvieira
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Addressed partially on #7 .

@ao60337 ao60337 self-assigned this Jan 19, 2023
@ao60337 ao60337 removed their assignment May 30, 2023
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